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MCDB 1B
Lecture 11
11
Biology
Undergraduate 2
02/10/2009

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Term
Sensory cells
Definition

-transduce physical or chemical stimuli into signals that are transmittable and interpretable

-Most are modified neurons,
specialized for detecting different kinds of
stimuli, such as pressure, heat, or light

Term
membrane receptor
proteins
Definition
detect a stimulus and respond by
altering the flow of ions across the plasma
membrane
Term
Sensory systems
Definition
include the sensory cells, the
associated structures, and the neuronal networks that
process the information
Term
ionotropic sensory detection
Definition
the receptor protein
itself is part of the ion channel and, by changing its
conformation, opens or closes the channel pore
Term
metabotropic sensory detection
Definition
the receptor protein is linked to a G protein that activates a cascade of intracellular events that eventually open or close ion channels.
Term
Primary sensory cells
Definition
generate action potentials
directly. An example is the crayfish stretch
receptor.
Term
Secondary sensory cells
Definition
generate action potentials indirectly by inducing the release of neurotransmitter.
Term
adaptation
Definition

-when sensory cells respond less when
stimulation is repeated

-The ability of animals to ignore continuous
stimuli while remaining sensitive to changing
stimuli

Term
Olfaction
Definition

-the sense of smell, depends on chemoreceptors.

-In vertebrates, olfactory sensors are neurons
embedded in a layer of epithelial cells at the top of the nasal cavity

-The axons of these sensors project to the olfactory bulb of the brain

Term
olfactory receptor protein
Definition
each protein binds to particular odorant molecules, which activates a G protein. The G protein then activates an enzyme that increases the level of the second messenger cAMP. cAMP opens a Ca2+ channel.Ca2+ leads to opening of a Cl- channel which
depolarizes the membrane and an action potential is
fired.
Term
pseudogenes
Definition
genes that have mutations
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