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sensory neuron connected to a motor neuron connected to a muscle cell |
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specialized cells of the nervous system that recieve, encode and transmit information -neurons + glial cells make up the nervous system -composed of four regions - cell body, dendrites, axon, and axon terminals |
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recieve information and convert or transduce it into electrical signals |
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-muscles and glands -recieve signals communicated from the nervous system to cause behavioral or physiological response |
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cluster of neurons -frequently one pair of ganglia is larger and more central in an organism and is given the designation "brain" |
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CNS - central nervous system |
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In vertebrates, most of the cells of the nervous system are found in the brain and the spinal cord, which together are called the central nervous system -information is transmitted to the CNS via sensory cells and from the CNS to effectors via neurons |
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PNS - peripheral nervous system |
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Neurons and supporting cells found outside the CNS |
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contains the nucleus and most of the cells organelles |
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projections from the cell body that bring information from other neurons or sensory cells to the cell body |
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carries information away from the cell body -conduct information to target cells (other neurons, muscle cells, or gland cells) |
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located at the end of the axon, it has many fine nerve endings -the axon terminal is positions very close to the target cell -nerve impulses cause the release of neurotransmitters (chemical messengers) into the synapse |
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the difference in voltage across the plasma membrane of a neuron -of a resting axon is about -60 miliVolts mV |
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the voltage difference in an unstimulated neuron |
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use energy to move ions against their concentration gradient -the major ion pump in neural membranes is the sodium–potassium pump (Na+/K+ ATPase), which expels Na+ ions from the cell, exchanging them for K+ ions from outside the cell -This keeps the concentration of K+ greater inside the cell than outside |
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are pores formed by proteins in the lipid bilayer that selectively allow ions to pass through. |
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potassium equilibrium potential |
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the tendency of K+ ions to diffuse into the cell is equal to their tendency to diffuse out |
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When the inside of a neuron becomes less negative in comparison to its resting condition |
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when the inside of a neuron becomes more negative in comparison to its resting condition |
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are action potentials that travel along axons. |
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-a sudden and major change in membrane potential that lasts for about 1–2 milliseconds at speeds up to 100 meter per second -During an action potential, the voltage changes from the resting potential of –60 mV to +50 mV, then rapidly returns to the resting potential -primarily caused by voltage-gated sodium channels -travel faster in large-diameter axons than in small-diameter axons and are self regenerating |
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the time when a plasma membrane cannot propagate an action potential |
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allows single ion channels to be studied |
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to increase the diameter of the axon, the axon is wrapped with myelin sheath |
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electrically insulates the axon (charged ions cannot cross the regions of the axon that are wrapped in myelin) |
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ion channels are clustered here in between myelin sheath |
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When an action potential fires at one node of Ranvier, it jumps to the next over the myelin sheaths |
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-Gradual destruction of myelin -autoimmune disease that affects the central nervous system (CNS) -no cure |
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A synapse is an axon terminal that contains many vesicles filled with chemical messenger molecules know as neurotransmitters |
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-is the neurotransmitter used by all vertebrate motor neurons -released when the vesicles fuse with the presynaptic membrane and moves into the narrow space called the synaptic cleft |
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If a postsynaptic neuron responds to chemical stimulation by depolarizing, the synapse is excitatory. |
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If the postsynaptic neuron hyperpolarizes, the synapse is inhibitory -(GABA) and glycine are most common |
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adds up the simultaneous influences of synapses at different sites on the postsynaptic cell -"several synapses fire at the sime time" |
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adds up postsynaptic potentials generated at the same site in a rapid sequence. -"same synapse fires rapidly" |
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