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MCDB 1B
Lectures 3 & 4
27
Biology
Undergraduate 2
02/10/2009

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Term
heterotrophs
Definition

organisms tha must obtain their nutrition by eating other organisms

-depend on the organic synthesis carried out by autotrophs

Term
autotrophs
Definition

organisms that trap solar energy using photosynthesis and use that energy to synthesize all of their components

-plants, some bacteria, and some protists

Term
calorie
Definition

the amount of heat required to raise the temperature of 1 g of water 1 degree

-a kilocalorie (Cal) is 1000 calories 

-being abandened for the joule

 

Term
basal metabolic rate
Definition
the metabolic rate resulting from all the physiological functions that take place at a resting state
Term
lumen
Definition
the cavity of the gut
Term
mucosa
Definition

first layer of tissue from the lumen

-consists of epithelial cells that have secretory and absorptive functions

Term
submucosa
Definition

just outside the mucosa

-contains blood and lymph vessels that carry absorbed nutrients to rest of body

Term
peritoneum
Definition
covers and supports all abdominal organs
Term
serosa
Definition
fibrous coat that surrounds the gut
Term
hydrolytic enzymes
Definition
break down protein, carbohydrate, and fat macromolecules into their simplest monomeric units
Term
mucus
Definition
consists of mucins (a family of large, heavily glycosylated proteins), and inorganic salts suspended in water
Term
amylase
Definition
a carbohydrase that hydrolyses starch into maltose
Term
pepsin
Definition

major enzyme produced by the stomach

-secreted by cells in the gastric glands as a zymogen called pepsinogen

-newly formed pepsin activates other pepsinogen molecules in a process called autoclasis

Term
ulcer
Definition
created when HCl comes in contact with the stomach wall
Term
helicobacter pylori
Definition
bacterium that infects the stomach and causes ulcers
Term
chyme
Definition
the mixture of gastric juice and partially digested food
Term
bile
Definition
secreted from the liver and flows through a branch of the hepatic duct to the gallbladder, where it is stored untill it is needed
Term
common bile duct
Definition
when fat enters the duodenum, bile is squeezed out of the gallbladder and into the common bile duct where it flows into the duodenum
Term
bile acids
Definition

are emulsifiers

have a lipophilic end and a lipophobic end and disperse fat cells intomicelles

-synthesized from cholesterol

90% are reabsorbed and recycled via the liver (enterohepatic circulation)

10% are lost with waste (major pathway for elimination of cholesterol)

Term
bile acid sequestrants
Definition

bind to the negatively charged bile acid and distrupts the enterohepatic circulation

-lowers cholesterol

Term
Lipases
Definition
break fats down to diglycerides, monoglycerides, and fatty acids so they can pass through the plasma membrane of the microvilli
Term
chylomicrons
Definition
water soluable lipoproteins synthesized from diglycerides, monoglycerides, and fatty acids
Term
lipoproteins
Definition

transport fats in the aqueous circulatory system

-consist of a core fat/cholesterol covered by apolipoproteins that make them water soluble 

-largest are chylomicrons

Term
Very low density lipoproteins (VLDL)
Definition
carry newly synthesized triacylglycerol from the liver to adipose tissue
Term
Low density lipoproteins (LDL)
Definition
carry cholesterol from
the liver to cells of the body. Sometimes referred to as
the "bad cholesterol" lipoprotein.
Term
High density lipoproteins (HDL)
Definition
collects cholesterol
from the body's tissues, and brings it back to the liver.
Sometimes referred to as the "good cholesterol"
lipoprotein.
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