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MCC Biology 1000 Professor K. Sak
Biology 1000 Ch 6 Metabolism: Energy & Enzymes
29
Biology
Undergraduate 1
09/25/2016

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Cards

Term

Ch 6 Question #1A

 

 

Know what metabolism means.  

Definition
Metabolism is a term that is used to describe all chemical reactions involved in maintaining the living state of the cells and the organism
 
Term

 Ch 6 Question #1B



Know the 2 types of metabolism.

Definition
Metabolism is divided into two categories:
Catabolism - the breakdown of molecules to obtain energy

 

 

Anabolism - the synthesis of all compounds needed by the cells using energy
Term

 Ch 6 Question #2

 


Know what is the energy molecule of the cell. 

Definition
Cells make ATP – the energy molecule – to carry out many functions of the cell that require the input of energy
Term

Ch 6 Question #3A



Know what energy is the types (kinetic energy and potential energy).   

Definition
Kinetic energy
Energy of motion     Mechanical

Potential energy
Stored energy      Chemical  energy

Term

Ch 6 Question #3B



What kind of energy do chemical bonds have?  

Definition
Term

Ch 6 Question #3C



What happens when a chemical bond is made or broken?

Definition
Chemical energy
Making/breaking a chemical bond can release energy.

 

Making/breaking a chemical bond can require energy. 
Term

Ch 6 Question #4

 


Know the first law of thermodynamics and what it means. 

Definition
Thermodynamics is a branch of physics that studies heat and temperature and their relation to energy and work. 

First law:
Law of conservation of energy
Energy cannot be created or destroyed, but can be changed from one form to another
Term

Ch 6 Question #5A



Know the second law of thermodynamics and what it means. 




Definition
Second law:
Law of entropy - energy conversions increase the disorder of the universe. 
When energy is changed from one form to another, there is a loss of usable energy. 
Waste energy goes to increase disorder. 

             In most transformations, the unusable energy is converted to heat. 

Term

Ch 6 Question #5B



Know the second law of thermodynamics and what it means. 

Definition

 

Second law Continue:

Heat cannot be stored or used in any in reactions

It is basically LOST and considered a disordered from of energy, thereby, increasing the disorder of the universe
 
Term

Ch 6 Question #6A


What does exergonic mean?   



Definition
Exergonic Reactions- Products have less free energy than reactants (release energy)

              When reactants “react” to make products energy is released.


Exergonic reactions release energy
These reactions release the energy in covalent bonds of the reactants

              Burning wood releases the energy in glucose as heat and light

Term

Ch 6 Question #6B


What does endergonic mean?

Definition
Endergonic Reactions- Products have more free energy than reactants (require energy input).

                When reactants “react” to make produce energy is required.

Endergonic reactions
Begin with reactant molecules that contain relatively little potential energy but

 End with products that contain more chemical energy

 
Term

Ch 6 Question #7A



Know the structure of ATP.  

Definition
Composed of:
Adenine, ribose (together = adenosine), and three phosphate groups

 

Need ENERGY to make ATP
Term

Ch 6 Question #7B



Why is ATP important?

Definition
Adenosine triphosphate (ATP)
High energy compound used to drive, supply the energy for, metabolic reactions

 

Constantly being generated from adenosine diphosphate (ADP)
Term

Ch 6 Question #8


 

  1. What are coupled reactions?






Definition
Coupled reactions:
Energy released by an exergonic reaction captured in ATP

 

ATP is used to drive an endergonic reaction
Term

Ch 6 Question #9A



Know what a  metabolic pathway is.

 

Definition
Chemical Reactions usually occur in a sequence
Products of an earlier reaction become reactants of a later reaction

 

Such linked reactions form a metabolic pathway.
Term
Metabolic Reactions and Energy Transformations
Definition

 

Free energyis the amount of energy available to perform work after a chemical reaction has occurred. 

Metabolism
Sum of cellular chemical reactions in cell
Reactants participate in a reaction
Products form as result of a reaction
Term

Ch 6 Question #10A Know ALL about enzymes.   



What is an enzyme?  

Definition
Enzymes are catalysts – help to speed up chemical reactions
Enzymes are proteins made by the cell

 

Exception:  Some enzymes that are made of RNA
Term

Ch 6 Question #10B Know ALL about enzymes.  



What do enzymes lower?  

Definition
pH
Most enzymes are optimized for a particular pH.
The enzymes in your stomach, pH 2, work best in acidic conditions.
The enzymes in your intestines, pH 8, work best in slightly basic
conditions.
The enzymes in your blood, pH 7.4, work best in a neutral
condition.
An enzyme placed in the wrong pH will also be denatured.
Term

Ch 6 Question #10C Know ALL about enzymes.  



What is a substrate?  

Definition
The specific reactant that an enzyme acts on is called the enzyme’s substrate.

Enzymes are specific because their active site fits only specific substrate molecules.

Enzyme-Substrate Complex:
Degradation:
     ▪Enzyme complexes with a single substrate molecule
     ▪Substrate is broken apart into two product molecules
Synthesis:
Enzyme complexes with two substrate molecules
Substrates are joined together and released as a single product molecule
Term

Ch 6 Question #10D Know ALL about enzymes.  



What is the active site? 

Definition

 

The active site has a shape that only a specific reactant can fit. 
Enzymes are specific because their active site fits only specific substrate molecules.
There are ~ 75,000 enzymes thought to exist in the human body. 
Term

Ch 6 Question #10E Know ALL about enzymes.  



Why is an enzyme specific?  

Definition
Enzyme “folding” dictates its function which makes them specific to the reaction they catalyze

 

The folding creates an ACTIVE SITE
Term

Ch 6 Question #10F Know ALL about enzymes.  



What is a cofactor?  

Definition
Cofactors bind to the active site and help in the catalysis of the reaction.

 

Cofactors are inorganic, such as zinc, iron, or copper.
Term

Ch 6 Question #10G Know ALL about enzymes.  



What is a coenzyme?  

Definition

 

Coenzymes are non-protein organic molecules, such as most vitamins.
Term

Ch 6 Question #10H Know ALL about enzymes.  



What is a enzyme inhibition?

Definition

Enzyme Inhibition


Reversible enzyme inhibition

A substance known as an inhibitor binds to an enzyme and decreases its activity.


Competitive inhibition– the substrate and the inhibitor are both able to bind to active site.


Noncompetitive inhibition– the inhibitor does not bind at the active site, but at an allosteric site (another place on the enzyme.

Term

Ch 6 Question #11

 

 

Know the factors that affect enzymatic speed.

 

Definition

Factors Affecting Enzymatic Speed


Cells can regulate the presence/absence of an enzyme.
Cells can regulate the concentration of an enzyme.

 

Cells can activate or deactivate some enzymes through cofactors and
coenzymes.
Term
Ch 6 Question #12A 
 
 
Know what organelles are involved in energy in the cell.  
Definition
Need Organelles
Chloroplasts

 

Mitochondria
Term

Ch 6 Question #12B



What are the 2 processes?




Definition

Organelles & the Flow of Energy


Oxidation-reduction (redox) reactions


Electrons pass from one molecule to another

            •Oxidation- loss of an electron

            •Reduction – gain of an electron

Both take place at same time

One molecule accepts the electron given up by the other

Term

Ch 6 Question #13


 

Know what the electron transport chain is.

 

Definition
Consists of membrane-bound carrier proteins found in mitochondria and
chloroplasts.
Physically arranged in an ordered series:
Starts with high-energy electrons being delivered

 

Pass electrons from one carrier to another
Term

Ch 6 Question #14



Know how chemiosmosis works.

Definition
The electrochemical gradient is used to make ATP from ADP – Chemiosmosis
Ends with low-energy electrons and high-energy ATP
 

 

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