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MCB Translation/Regulation
by Chelsea (complete)
8
Medical
Graduate
02/20/2009

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Cards

Term
What happens in the nucleolus?
Definition
Genes that encode rRNAs make the small and large ribosomal complexes.
Term
Where is the genetic code most degenerate?
Definition
In the third position (the 3' end).
Term
What enzyme must recognize the genetic code?
Definition
Amino-acyl tRNA synthetase. They add one amino acid to a tRNA.
Term
What happens if eIF-2 is phosphorylated?
Definition
Translation is slowed down.
Term
What does eIF-2 do?
Definition
It helps the first Met tRNA get into the p site on the large ribosomal subunit. It also encourages the use of the first AUG. Polio destroyed eIF-2 and caused internal translation.
Term
What is EF-Tu-GTP involved in?
Definition
It tests the fit of the codon with the A site.
Term
What is eRF?
Definition
It is a transcriptional release factor and a g-protein that hydrolyzes GTP.
Term
What happens after the SRP:ribosome:mRNA complex docks with the receptor on the ER?
Definition
An exchange of GDP for GTP, and release of SRP. The peptide then travels down a pore and pushes into the ER where it is "born."
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