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MCB TEST 1
Nervous/Muscles/etc.
107
Biology
Undergraduate 1
09/11/2006

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Term
Cell Membrane
Definition
proteins regulate flow in/out of cell
Term
Cytoplasm
Definition
complex network of filaments & tubules called cytoskeleton / fluid part = cytosol
Term
Rough ER
Definition
ribosomes attached, protein synthesis
Term
Smooth ER
Definition
helps lipid metabolism
Term
Golgi Apparatus
Definition
transporter btwn diff organelles
Term
Lysosomes
Definition
Garbage Crew
Term
Peroxisomes
Definition
membrane ound vescicles; contain digestive enzymes for fatty acids
Term
Myosin
Definition
motor molecule; tells what action to do for the filament
Term
Apical or Mocosal surface
Definition
faces the environment or the lumen of a particular organ
Term
Basal Surface
Definition
located close to blood vessels; lateral side face neghbroing epithelial cells
Term
Lateral Surface
Definition
keep leakage out
Term
Desmosomomes:
Definition
areas with tight adheision between cells; give tissue structure; stops leaks
Term
Microvilli
Definition
increase surface area on Apical surface; helps with transport or molecules across epithelial layer
Term
PNS
Definition
sensory/motor; has all the neuronetwork in the body besides spine cord/brain; motor effectors (skeletal muscles/smooth)
Term
CNS
Definition
brain/spinal cord; process sensory info and produce motor commands
Term
Resting Potential
Definition
when a membrane is at rest it depends on the amount of ions and the amount of protein reeptors....Na outside/K- inside
Term
Action Potential
Definition
"all or none" when sodium levels reach a certain threshold the transmittion is sent
Term
Cytokinesis
Definition
two daughters cell seperate; "furrow" (narrowing) shows until the cell is split in two
Term
DNA Replication: Interphase
Definition
DNA replicates; DNA directs RNA/protein synthesis; centrosomes duplicate
Term
DNA Replication: Prophase
Definition
nuclear envelope breaks down; dna copies from chromosomes; centrosomes seperate; they organize microtubules; mitotic apparatus
Term
DNA Replication: Metaphase
Definition
Nuclear envelope dissapears; chromosomes line up @ equator
Term
DNA Replication: Anaphase
Definition
Microtubules attach to proteins; sister chromatids pulled by microtubules
Term
DNA Replication: Telephase
Definition
Nuclear envelope around chromosomes (2 nuclei & 2 nucleoli; chromosomes unveil --->chromatin; spindle fiber dissapears
Term
Transcription
Definition
DNA blueprint copied to RNA; copies the codon (complimentary pairs of DNA)
Term
Translation
Definition
mRNA and tRNA mix thogether through complementary base triples being linked through peptide bonds
Term
IPSP
Definition
Inhibitory postsynaptic potential; stops motor neuron
Term
EPSP
Definition
Excitatory postsynaptic potential; initiats motor neuron
Term
Synaptic Summation
Definition
algebraic accumulation of synaptic potential at receptive surface
Term
Spatial Summation
Definition
presynaptic input is summed up and analyzed acroos different synaptic sites, impinging on the same postsynaptic neuron
Term
Temporal Summation
Definition
accumulates individual synaptic potential in time; increase in frequency of discharge (impulse/unit time) enhances effectiveness of synapses
Term
Actin
Definition
thin filaments dissapear (I-band) of muscle
Term
Myosin
Definition
thick filaments dessappear (a-band)
Term
Tropomyosin
Definition
covers actin filaments during muscle relaxation; no cross bridging
Term
Troponin
Definition
serves as a "handle" for tropomyosin, when Ca++ is inbound,it moves tropomyosin out of the way and allows contraction to happen
Term
Sarcoplasmic reticulum (SR)
Definition
hols Ca++
Term
Rigor Mortis
Definition
ATP used up; myosin heads remain locked to actin filaments; muscles become rigid and resist contracting or stretching
Term
Mechanoreceptor
Definition
displacement, stretch and sound
Term
Light Touch receptors
Definition
Meissner's carpuscle, Merkel's disk, hair root plexi
Term
Crude Touch Receptors
Definition
Krause's endbulb, Ruffini's ending, PACINIAN CORPUSCLE**
Term
Receptors in muscle: Tendon Length/tension
Definition
golgi tendon organ
Term
Receptors in muscles/tendons:

displacement/positon
Definition
joint receptors or kinesthetic receptors
Term
hair cells (location)
Definition
cohlea/vestibular apparatus
Term
(1) baroreceptors & (2) stretch receptors
Definition
(1) in walls of certain arteries; measure distention from blood pressure; (2) in stomach and intestinal distention
Term
Chemoreceptors (name the different functions and organs)
Definition
1. olfactory receptor cells
2. taste receptor cells
3. sensor cells in the carotid and aortic bodies detect oxygen
4. brain medulla detect CO2
5. Osmoreceptors: regulate osmolarity by detecting sodium levels
6. Glucoreceptors: regulate blood glucose levels
Term
Phot Receptors (organs/functions)
Definition
1.rods: more abundant/sensitive; peripheral and night vision
2.Cones: detect R, G, B
Term
Thermoreceptors
Definition
1. Free nerve ending in skin/nociceptors respond to stimuli from pain
2. certain neurons in hypothalmus regulate blood temp
Term
Pacinian Corpuscle (functions/location)
Definition
found in deep tissue/visceral tissue; vibrations and pressure (crude touch)

consists of the nerve ending of a mylenated snesory fiber wrapped in a fibrous connective tissue capsule
Term
Receptor Adaptation
Definition
decrease or stop firing even if stimulus continues

Adapting:
fine touch/pressure (fast)
joint/muscle mechanoreceptors (slow)
Nonadapting:
pain
Term
Seperate RF
Definition
when peripheral brances of two adjacent units are far apart, the stimuli on one will not active the other (i.e. back)
Term
Overlapping RF
Definition
stimuli of one unit will start other units to activate but to a certain degree (fingertips)
Term
Spinothalmic pathway
Definition
(pain, temp, crude touch)
LATERAL DIVISION: pain/temp
ANTERIOR(VENTRAL DIVSION: crude touch

end @ the nucleus region of the thalamus
Term
Dorsal Column
Definition
(fine touch, pressure, and proprioception)
end in brain medulla for first synapse; secondary-order sensory cells ascend the medial lemnisucus and end with spinothalmic
Term
discrimitive tactile pathway
Definition
stimuls source, fine touch, vibrations, stereogenesis, limb/body positon
Term
Secondary Cortex (3rd order neurons)
Definition
fine tune sensory messages; send descending sensory control fibers to relay stations to regulate the quality and quantity of messages arriving in cortex
Term
Sensory Map
Definition
shows the sensations that the brain can detect
Term
Difference between Sharp pain/Slow pain
Definition
Sharp: 10x faster than C-fiber; thin but mylineated

Slow: unmylenated nerve fiber; goes through reticular formation to arise pain
Term
Central Pain Inhibition
Definition
electrical stimulation of the preiaqueductal gray region. inhibits pain in the conscious animal
Term
Endorphins (enkephalins)
Definition
seretonin released, excited dorsal horn to release it...suppress relay of pain signals by afferent c-type fibers
Term
Gate Theory of Pain inhibition
Definition
when in pain, exciting the fast pain nerve fibers, it enduces the dorsal horn to activate inhibitory neurons
Term
Referred pain
Definition
usually caused by pain fibers converging onto the dorsal horn relay cells. and the convergence may involve fibers from diff body parts
Term
Phantom Pain
Definition
pain from an amputated limb;

Solution: can be cured by rearrangement of the sensory map through imagining the limb still exists
Term
Cornea
Definition
refrats the rays inward (convex)
Term
Lens
Definition
parrelel rays to a focal point...can focus on distance by actively changing curvature
Term
Iris
Definition
controls pupil

sphincter contracts
dilator widens
Term
accomodation reflex
Definition
the lense's ability to change curvature
Term
Presbyopia
Definition
total loss of accomodation
Term
astigmatism
Definition
defect in the curvature of cornea
Term
Why is Melanin in the back of the eye?
Definition
because in the back of eye it stops reflection of light and glare
Term
Photoreception
Definition
retina's outermost layer responds to light and dark then sent to brain
Term
Phototransduction
Definition
PR cells to bipolar cells to ganglion cells to brain
Term
Fovea vs Periphery
Definition
Fovea: day vision, color vision, sprecise vision

Retinal Periphery: night vision
Term
Rhodopsin
Definition
in rods, photoreceptor protein molecule
Term
Transducin
Definition
increases rod cell membrane potential by reducing cGMP--->opens Na channels
Term
Superior Colliculi
Definition
coordinates accomodation and light reflexes as well as some eye/head movement
Term
Primary Visual Cortex (PVC)

what can it make out?
Definition
Lines, orientations, simple colors
Term
Outter Ear (organs within)
Definition
Pinna, Auditory Canal, Tymanic membrane
Term
Middle Ear (organs within)
Definition
Malleus, Incus, Stapes
Term
Inner Ear (organs within)
Definition
oval window, cochlea, auditory nerve, round window
Term
Cochlea
Definition
basilar membrane funs inside cochlea (supports hair cells)
Term
Olfactory Receptor Nuerons
Definition
1. olfactory cilia are olfactory receptors
Term
Number of Olfactory
Definition
roughly 1000
Term
Spinal Cord (SC) Function
Definition
(1)nerve center: integrating the incoming sensory signals/activate motor output w/o brain intervation (2) intermediate nerve center betwen periphery system and brain
Term
White Matter
Definition
myelinated nerve fiber axons; brain = descending SC = ascending
Term
Somatic Reflexes (function)
Definition
body's skeletal muscles and motor behavior
Term
Autonomic reflexes
Definition
help regulate the internal environment by affecting exocrine gland hear with veisceral smooth muscle.
Term
Reflex Arc (the WHOLE tract)
Definition
1. detect stimulus 2. afferent nerve: conveys sensory signal to SC/brain 3. integrate synaptic crater - analyze sensory input/produces motor output commands 4. efferent nerve: conducts the motor output to the periphery 5. motor effector carries out respons regulator.
Term
Y gamma nuerons (Y efferents)
Definition
small spinal neurons,stimulated by sensory fibers from periphery and by neurons from the higher brain motor centers.
Term
Postsynaptic Reflexes
Definition
the reflex arc involves one or more interneurons and higher # of synaptic connection
Term
Alpha & Motor Neurons
Definition
are large nuerons that excite the ordinary muscle fibers (extrafusal) (do both exciting of muscles and returening the muscle fiber to the original length)
Term
Withdrawl Reflex
Definition
(limb flexor relfex)/ noxious (sharp or hot) stimuli active the ain receptors and their sensory fibers
Term
Crossed extension
Definition
mediation of spinal reflexes by assocaitve interneurons
Term
Basal Ganglia (BG)
Definition
in forebrain; work together with motor areas of cortex and cerebellum to plan and coordinate lots of voluntary movements
Term
Parkinson's Disease
Definition
basal ganglia lesions produce pronounted motor disorder....AKA can't initiate voluntary movement
Term
Primary Motor Cortex
Definition
Map of the body's muscles (motor homunculus) -->proportional to the degree of motor control and skilled movement
Term
Corticospinal Tract (CS TRACT)/upper motor neurons
Definition
controls all trunk and limb movement
Term
Corticobulbar Tract
Definition
regulate speech tongue, and head movement
Term
Premotor Area
Definition
communicates with basal ganglia and cerebellum....**planning of movement and recruitment those above...and other motor areas for initiation of voluntary movement (sometimes it actually deploys neurons)
Term
Cerebellum (fxns)
Definition
receives input from premotor cortex ---> analyzed by CB cortex circuts ---> outcome is relayed to deep CB nuclie by Purkinje cells (release GABA (inhibitory))
Term
Vestibularcerebellum
Definition
balance/eye movement
Term
Spinocerebellum
Definition
posture and locomotion
Term
Cerebrocerebellum (consists of cerebellum hemisphere)
Definition
skilled movements;
Term
cerebellum hemisphere (input? output?)
Definition
input: premotor cortex ---- output: thalamus
Term
1 parsec
Definition
3.26 light years...earth's radius to turn 1 arcsec
Term
core collapse
Definition
(electron degeneracy) past 1.4 solar masses--->core collapse--->core transformed into sea of neutrons (electrons squeezsed into protons, neutrinos released)
Term
Neutron Star
Definition
1.4-2 Solar Masses
Supported by Electron Degeneracy (neutrinos)
Very Small Diameter (20km)
Term
Pulsars
Definition
(every 1.337 sec.)
After collapse spin and magnetic field strength increases; magnetic field bemas radiation into space
Term
Special Relativity
Definition
1. The speed of light is constant for everyone. it's the fastest possible speed in the universe.
2. The rules of physics are identical for everyone, no matter their speed.
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