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MCB Chapter 13 Cards
Chapman
23
Microbiology
Undergraduate 2
12/13/2012

Additional Microbiology Flashcards

 


 

Cards

Term
lambda phage synthesis
Definition
phage genes transcribed by host RNA pol
mRNA translated by host
phage DNA replicated
Term
integration of phage DNA
Definition
phage repressor protein is active
most phage genes are not expressed
site specific recombination occurs with host chromosome
phage DNA becomes part of host chromosome
Term
polio virus
Definition
picornaviridae
small
non-enveloped
+ strand virus
entero virus
icosahedral
can lead to muscle paralysis
fecal-oral
Term
poliomyelitis
Definition
polio spreads to nerve cells
causes paralysis of muscles innervated by affected cells
only happens in <1% of patients with polio
Term
HIV
Definition
retrovirus
targets t-helper cells
fuses with host cell cytoplasmic membrane
ss+
8000 bp
95 nm
Term
retrovirus
Definition
viral genomse is RNA
DNA copy is made, inserts into host chromosome
have envelope
released by budding
Term
smallpox
Definition
dsDNA
200,000 bp
250 nm
Term
herpes simplex 1
Definition
dsDNA
200,000 bp
110 nm
enveloped
causes cold sores and blisters
Term
hep B
Definition
dsDNA
3000 bp
enveloped
42 nm
hepadnaviridiae
icosahedral
transmitted by blood transfusions, needles, and other bodily fluids
5000 die from liver cirrhosis
1000 die from liver cancer
Term
influenza
Definition
ss- RNA, segmented
17,000 bp
enveloped
100 nm
8 pieces of RNA inside a matrix
severe upper respiratory infection
damages mucosal epithelial tissue
Term
Rhinovirus
Definition
ssRNA+
6000 bp
30 nm
cause common cold
Term
rubella
Definition
ss+ RNA
14,000 bp
45 nm
German measles
togoviridiae
icosahedral
mild fever
rash of small red spots
can cross placental barrier
Term
rubeola
Definition
red measles
caused by parmyxoviridae
-ssRNA
helical capsid
airborne
rash, Koplik spots (red spots with white centers in mouth)
fever, cough, conjuctivitis
Term
Hep A
Definition
picornaviridae family
nonenveloped
fecal-oral
+ssRNA
jaundice, fatigue, fever, nausea, appetite loss
resolve in 4-6 weeks
inflammation of liver
Term
HPV
Definition
papovaviridae
causes genital warts
attacks growing cells
non-enveloped
circular dsDNA
requires host DNA pol
linked to cervical cancer
Term
rabies
Definition
bullet-shaped
rhaboviridae
infects CNS
long incubation
zoonosis
tropism-- nerve cells
dementia, fever, depression, drooling
RNA virus
Term
Ebola
Definition
hemorrhagic fevr, often fatal
filoviridiae
-ssRNA
surrounded by tube of capsule proteins
80% of infected die
Term
yellow fever
Definition
hemorrhagic fever
mosquito borne
Term
herpes simplex 2
Definition
associated with mucosal epithelial tissues of genital regions
can become latent
Term
chickenpox
Definition
varicella zoster virus
herpesvirus family
spread by direct contact
tropism is respiratory epithelial tissues
can infect liver, spleen and skin and nerve ganglia
skin lesions shed the virus
Term
viroid
Definition
infectious particles
seen in plants
lack a capsid
Term
prion
Definition
infectious particles
lack nucleic acid
regulate expression of certain genes
appear to be able to convert normal protein to abnormal shape
Term
rotovirus
Definition
fecal-oral pathogen
causes viral diarrhea
infects and kills intestinal epithelial cells
fluids leak into intestinal lumen
segmented dsRNA
icosahedral, no envelope
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