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MCB 2000 Exam 3
Exam 3 material
36
Microbiology
Undergraduate 2
11/07/2011

Additional Microbiology Flashcards

 


 

Cards

Term
What is an Arbovirus 
Definition
  • an athropod- borne virus 
Term
arthropod diseases
Definition
diseases carried by insects
Term
Arboviral Encephalitis
Definition
  • caused by an arbovirus that crosses brain-blood barrier
  • no treatment (supportive)
  • reduce contact with mosquitos to prevent 
  • vaccines avaliable for horses
Term
Diseases of the Nervous System (Types)
Definition
bacterial, viral, fungal, prion
Term

How does skin ward off infection?

name/describe two layers of skin

Definition
  • dry, cool, low pH, high salt concetration
  • epidermis (dead skin cells that shed) dermis (living skin cells, blood supply and inervated) 
Term

1.     Which bacteria cause folliculitis? What are different forms of the disease?

Definition
  • caused by  Staphylococcus 
  • sty (eye), furuncles, carbuncles 
Term

1.     List and describe the mode of action of various virulence factors possessed by Staph

Definition
capsule, coagulase (clotting), exfoliation, hyaluronidase (spreading factor), leukocidin, lipase, proteases, protein A (neutalizes antibody), TSS 
Term

1.     What makes Staph resist phagocytic cells? Name other bacteria resistant to phagocytosis

Definition
  • capsules help staph resist phagocytosis
  • streptococcal pyogenes also resist phagocytosis 
Term

 Name several systemic infections

Definition
Infectious Mononucleosis, Malaria, Histoplasmosis, tertiary syphilis, leishmaniasis, 
Term

    What are the important features of plague? How one can control the disease?

Definition
  • caused by  Yersiniapestis     
  • 2 types: bubonic (lymph) pneumonic (lungs) 
  • carried by rodents, transmitted by fleas (zoonotic) 
  • you can control the disease by avoiding rodents?
Term

 Explain how a simple foot infection may result in developing gangrene.

Definition
gangrene developes when a deep wound becomed infected and cuts off  oxygen to the tissue. This causes the tissue to die
Term

What is LPS? What are the consequences of release of LPS?

Definition
LPS is an endotoxin that is released when the bacteria dies. Consequences include inflammation, fever, shock, and DIC (cut off of blood flow to parts of the body)
Term

 Name the antibiotic used to treat Staph infections. Why resistance to this drug is an issue

Definition
Methicillin. Resistance is an issue because people with MRSA can not be treated with normal antibiotics
Term

    Compare and contrast impetigo and erysipelas. 

Definition
impetigo is caused by staph and strep and usually affects children and teens. erysipelas is caused only by strep and affects older adults. Both infections of the skin, usually itchy pus-filled bumps and rashes. Also both transmitted by person to person contact.  
Term

 Which genus of organisms is the most infectious to human?

Definition
Streptococci 
Term

    Define and give several examples of Zoonotic diseases

Definition
  • a disease spread from animals to humans
  • examples: plague, lyme disease 
Term

   Name diseases caused by Strep pyogenees. Name the virulence factors possessed by this organism

Definition
  • necrotizing fasciitis, scarlet fever, rheumatic fever
  • Pili, M protein, capsule (hyaluronic acid), hyaloronidase (spreading factor), streptolysins s an o (kills human cells), pyrogenic exotoxins (causes fever), bacterimia (spread through blood system) 
Term

    What are the characteristics of the disease called necrotizing fasciitis?

Definition
  • caused by strep pyogenes
  • virulence factors: streptokinase (dissolves blood clots) hyaluronidase, exotoxin A, steptolysin s
  • person to person, breaks in the skin
  • treated by antibiotics 
  • progresses quickly, can be deadly 
Term

1.     Describe how acne bacteria damages the skin

Definition

caused by Propionibacterium acnes

obligate anaerobe meaning it must penetrate deep into skin to infect. 

Term

  What is the most important characteristic of Pseudomonas aeruginosa?

Definition
it is the most common opportunistic infection
Term

  Name two infections caused by anthrax bacteria

Definition
cutaneous and inhalation anthrax
Term

   What is the difference between chickenpox and shingles? What is meant by recurrent infections?

Definition
chickenpox is the initial infection and shingles is the recurrent infection. Recurrent infection is one that comes back, sometimes worse than before, after lying dormant for years. 
Term

   What are the different type of skin infections caused by fungi? Define mycosis.

Definition
  • mycoses are diseases caused by fungi
  • Dermatophytoses
  • Chromoblastomycoses
  • Phaeohyphomycoses
    Mycetomas
Term

   Name and describe two skin infections caused by parasites.

Definition

Leishmaniasis-skin and systemic, spread by sand fly (Gulf war syndrome) affects mostly AIDS patients

Scabies-itching and rash, transmitted by mites but usually caught from prolonged contact (ex. sex) treated with lotion and cleaning of infected clothing 

Term

     Define conjunctivitis, kertitis,  and trachoma. 

Definition

conjunctivitis- inflammation of conjunctiva 

keratitis- inflammation of the cornea 

trachoma- caused by chlamydia, found in newborns, can lead to blindness 

Term

What is meant by neurotropic and lymphotropic viruses?

Definition
neurotropic viruses are spread through the nervous system, and lymphotropic viruses are spread through the lymph system
Term

  What is DEET?

Definition
insect repellent associated with lyme disease
Term

     What are the important features of Lyme disease?

Definition
  • zoonotic disease (ticks)
  • caused by Borrelia
  • rash, neurological symptoms, severe arthritis 
  • treated with antimicrobial drugs in early stages 
Term

1.     What are the components of CNS? Name the normal flora of CNS. Name two diseases associated with CNS. How active is the immune system in CNS?

Definition
  • brain and spinal column
  • NO normal flora 
  • menigitis and rabies 
  • there is no immune system in the CNS
Term

   What is blood-brain barrier?

Definition
filtering mechanism that blocks the passage of certain substances 
Term
Bacterial Meniningitis (general characterisitics) 
Definition
  • inflammatory bacterial infection of the meninges 
  • VERY dangerous but rare
  • signs/symptoms: sudden high fever, inflammed cranial or spinal meninges
  • diagnosed by spinal tap 
  • treated with antimicrobial drugs
  • there are vaccines
Term
Bacterial Meningitis (caused by)
Definition
  • streptococcus pneumoniae (leading cause in adults) 
  • neisseria meningitidis (fimbria, capsule, LOS (endotoxin)
  • haemophilus influenzae (main cause of bacterial meningitis) 
Term
what are spores
Definition
dormant bacteria resistant to elements 
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