Term
| cistrons on primary transcript of RNA |
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Definition
encode separate polypeptides
-prokaryotic transcripts often polycistronic (multigenic) |
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Term
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Definition
| segment of DNA transcribed into RNA |
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Term
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Definition
antiparallel and complementary to the template strand
-always made in the 5' to 3' direction |
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Term
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Definition
mRNA – messenger - codes for proteins
tRNA – transfer - adaptor between mRNA and aa
rRNA – Ribosomal - structural component of the ribosomes - catalyzes protein synthesis
eukaryotes also have:
hnRNA – hetereogenous nuclear – intermediate form; pre-mRNA processed to make RNA
snRNA- small nuclear – needed for mRNA maturation; part of spliceosome
miRNA – microRNA - 22 to 24 nucleotides that control gene expression |
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Term
| prokaryotic transcription factors |
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Definition
| -initiates transcription and regulates binding of RNA polymerase to the promoter region upstream of the transcription unit |
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Definition
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Term
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Definition
-10 TATAAT nontemplate
(15-18 bp from -35 promoter region) |
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Term
| prok. transcription start site |
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Definition
| +1 5-9 bp from the TATAAT box, can be an A or G in the non template strand (purines) |
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Term
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Definition
| multimeric complex of ~20 polypeptides (900kDa) |
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Term
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Definition
| α-has a polymerase activity, ε has 3’ to 5’ exonuclease activity, θ stimulates proofreading activity of the ε subunit |
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