Term
| If a gene expresses polar overdominance, what will the offspring's phenotype be relative to the parents'? |
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Definition
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Term
| If a gene expreses polar underdominance, what will the offspring's phenotype be relative to the parents'? |
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Definition
| offspring will be smaller |
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Term
| If a gene expresses bipolar dominance, what will the heterozygous offspring's phenotype be relative to the parents'? |
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Definition
Somewhere in the middle.
e.g. giant X dwarf -> medium size |
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Term
True or False
The gene that is expressed is the imprinted gene |
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Definition
FALSE
-the imprinted gene is methylated, preventing transcription and therefore shutting down expression of the gene |
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Term
True or False
Callipyge expresses maternal imprinting overridden by the paternal phenotype |
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Definition
FALSE
Callipyge involved paternal imprinting, overridden by the maternal phenotype (if they have a maternal CLPG gene they will be normal) |
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Term
| Why are imprinted genes not expressed? |
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Definition
| -methyl groups attached to Cytosine in the DNA sequence prevent transcription factors from binding to promoters |
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Term
The 'central dogma' is DNA -> RNA -> PROTEIN.
If a gene is methylated, where does this process come to a halt? |
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Definition
| In between DNA & RNA, because transcription can't take place. |
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Term
| Which gene is expressed, the imprinted or non-imprinted gene? |
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Definition
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Term
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Definition
evidence as to whether two loci are likely to lie near eachother on the
chromosome and are therefore likely to be inherited together |
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Term
| What is a multipoint linkage |
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Definition
| when the location of a disease gene involves 3 or more linked loci |
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Term
| What is a reciprocal cross? |
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Definition
breeding
experiment to test if parental origin (ie maternal or paternal) influences
inheritance of a trait. |
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Term
| Who studied parental imprinting, and in what organism? |
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Definition
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