Term
|
Definition
a drug in an organic solute of ether or ethanol, which dries and leaves a flexible film |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
drug of vegetable origin in water |
|
|
Term
|
Definition
a liquid or semi liquid applied with friction to unbroken skin |
|
|
Term
what is the vehicle in a liniment |
|
Definition
|
|
Term
liniments can contain many active ingredients which have what properties |
|
Definition
soothing, stimulating, analgesic, rubifacient |
|
|
Term
What situation need caution for the word CREAM |
|
Definition
only to be applied to un broken skin |
|
|
Term
what is the definintion of a mixture? |
|
Definition
|
|
Term
what is the definition of an emulsion |
|
Definition
2 immiscible liquids stablised into a homogenous mass, with emulsifying agents |
|
|
Term
what is a feature of buffered solution |
|
Definition
stable to changes in pH ie on skin |
|
|
Term
|
Definition
moistened mass of vegetable material and clay heated before application used to reduce inflammation and pain |
|
|
Term
what are 2 types of solid preparations |
|
Definition
1. for broken skin (ie an antibiotic powder), 2 for intact skin (eg dusting powders) |
|
|
Term
why should dusting powders only be used in intact skin? |
|
Definition
because in wounds the dust particles may act as a foreign body, and lead to formation of granulomas and gas gangrene secondary to contamination with clostridium |
|
|
Term
|
Definition
take up excretions from the body |
|
|
Term
what is glycerin primarily used as, and what are its other properties? |
|
Definition
mainly a absorbent... but also highly hygroscopic, emollient, lubricant, anti-septic |
|
|
Term
what are the properties of Calamine lotion |
|
Definition
an absorbent, made of Zinc carbonate, which is soothing, atringent, and will absorb 1 1/2 times its weight in moisture |
|
|
Term
Discuss 3 properties of melonin? |
|
Definition
1. highly absorbent acrylic fibre bondeed with a thin polyester film, allows drainage and is non stick, maintains wound moisture |
|
|
Term
|
Definition
an agent that arrests or diminisheds the flow of blood, a styptic |
|
|
Term
what are some example of a haemostatics? |
|
Definition
FeCl3 (ferric chloride), AgNO3 (silver nitrate), calcium alginate dressings |
|
|
Term
how do many hameostatics work? |
|
Definition
reduce capillary bleeding time by increasing the contractility and resistance and decreasing the permeability of capillary wall.... |
|
|
Term
|
Definition
lessen and relieve pain by removing cause (ie inflammation) or by changing response of perception of pain... |
|
|
Term
what re the classes of analgesics? |
|
Definition
opiates, non-opiates, corticosteroids, NSAIDs |
|
|
Term
|
Definition
lessen sensitivity to pain by acting directkly on nerve endings. by blocking action potentials |
|
|
Term
what are 3 types of anaesthetics? |
|
Definition
|
|
Term
what are 2 topical local anaesthetics? |
|
Definition
benzocaine (derivative of cocaine), and chloral hydrate |
|
|
Term
|
Definition
a spary/gel or ointment anaesthetic |
|
|
Term
what are the active ingredient of paraderm plus? |
|
Definition
chlorhexidine gluconate, lignocaine, and bufexamac |
|
|
Term
|
Definition
anti-septic, anti-inflammatory, and anaesthetic |
|
|
Term
what does a EMLA patch contain? |
|
Definition
lignocaine, and prilocaine |
|
|
Term
what are AE of EMLA cream/patches? |
|
Definition
oedema, itching, erythema, burning sensation |
|
|
Term
when are emla patches applied? |
|
Definition
|
|
Term
what are 3 types of anti-inflamatory agents? |
|
Definition
rubificients, heat and cold, NSAIDs, corticosteroids |
|
|
Term
you would use rubifacients for a chronic inflammation, t or f |
|
Definition
t, this will stimualte blood flow |
|
|
Term
what does a rubefacient do? |
|
Definition
produces local inflammation when applied to skin. the increased blood flow flushes metablites from areas of chronic inflammation and relieves congestion and stasis |
|
|
Term
when are rubifacients contraindicated? |
|
Definition
|
|
Term
rubifacients usually contact what ? |
|
Definition
camphor, menthol, iodine, methyl salicylate, eucalyptus oil, capsaicin |
|
|
Term
what are 4 mentioned of NSAIDs |
|
Definition
piroxicam (feldene), indomethacin (indospray), diclofenac (voltarin), ibuprofen |
|
|
Term
what are 2 important c/i or NSAIDs |
|
Definition
|
|
Term
how do corticosteroids act? |
|
Definition
on cells to reduce arachidonic nacid and hence prostaglandin production |
|
|
Term
how do corticosteroids affect other cells? |
|
Definition
decrease monocyte/macrophage activity |
|
|
Term
what are corticosteroid creams very useful for? when are they c/i? |
|
Definition
dermatitis, eczema....c/i where infection is present...(including fungal) |
|
|
Term
|
Definition
|
|
Term
which 2 mechs may anhydrotics work? |
|
Definition
|
|
Term
what are some examples of a anhydrotic... |
|
Definition
alcohol, aluminium acetate |
|
|
Term
what are 2 modes of action of astringents? |
|
Definition
1. protein precipitant (shrink cells of mucous membranes, dilute caustics, harden skin) 2 physical astringent (evaporate quickly on skin causing constricton of tissues,m ie evaporation ladss to cooloing) |
|
|
Term
what are some examples of astringents? |
|
Definition
aluminium, TBCo, cystal violet, AgNO3, Calamine, glycerin |
|
|
Term
|
Definition
soften and lubricates tissue |
|
|
Term
what are indications for emollients/ |
|
Definition
dermatitis, eczema, congenital icthyosis, dry skin conditions.. |
|
|
Term
when are 2 situations when an emollient is c/i? and what is a problem with emollients? |
|
Definition
hyperhydrosis, infection... the prob is that they can block skin glands , leading to folliculitis |
|
|
Term
urea, is a what? how does it act? |
|
Definition
keratolytic, which encourgaes absorption and retention of water by strat corneum |
|
|
Term
what is the use of an anaesthetic? |
|
Definition
surgery, enucleation of painful corns |
|
|
Term
|
Definition
|
|
Term
what are some example of antipuritics? |
|
Definition
benzocaine, rubifacients, calamine lotion, and withc hazel |
|
|
Term
discuss use of 20-40% ointment of salicylic acid? and the minimum and maximum return period? |
|
Definition
ID, digital and plantar HD, return min in 4-7 days, maximum 3/52 |
|
|
Term
what strength of salicylic acid is used for VP? |
|
Definition
|
|
Term
at what strength is salicylic acid fungicidal? |
|
Definition
|
|
Term
discuss solubility of salicylic acid |
|
Definition
colourless cystal soluble in water and alcohol |
|
|
Term
what is a key point of >10% of salicylic acid? |
|
Definition
whit rubbery coagulum forms, which accumulates, and should be removed to avoid infection |
|
|
Term
what is an antidote of Silver nitrate? |
|
Definition
|
|
Term
when should silver nitrate be avoided? |
|
Definition
|
|
Term
at <20% what is silver nitrate used for? |
|
Definition
|
|
Term
|
Definition
(silver nitrate btw) a irritant and caustic |
|
|
Term
|
Definition
|
|
Term
how does a keratolytic work? what is a it a subset of? |
|
Definition
break salt linkages between keratin molecules and allow H20 in to cause maceration, they soften rather than destroy str. corneum (a type of keratolytic) |
|
|
Term
how would silver nitrate be used for Hmolle, HD, nail sulci and heel fissues? |
|
Definition
20-25% sln, applied regularily for less than 2/52 |
|
|
Term
what is the use of 40-50% silver nitrate? how often is it applied? |
|
Definition
deep HD, NVHD, weekly, or every 3-4days to granulation tissue |
|
|
Term
when is trichloracetic acid used? |
|
Definition
for VP Rx, esp where there is less adipose tissue ie toes as it is gentler |
|
|
Term
describe 2 ways trichloracetic acid used for VP? |
|
Definition
1. debride callous, and soak lesion with solution, review in 4-14 days 2. apply a crystal to Vp for 30s, and review 4-14 days (stronger action). |
|
|
Term
what is the antidote for trichloracetic acid |
|
Definition
|
|
Term
How is glacial Acetic acid used? |
|
Definition
paint on VP, followed by AgNO3, 2-3 applications each visit, pain on HD/NVHD |
|
|
Term
what is the antedote of Glacial acetic acid? |
|
Definition
water, or bicarbonate soda |
|
|
Term
|
Definition
at risk, damaged skin, atrophic skin |
|
|
Term
what is the return for glacial acetic acid? |
|
Definition
min 4 days for VP as weak Rx, 14-12 days for HD |
|
|
Term
|
Definition
|
|
Term
|
Definition
skin cleanser that dissolves fats and resins and removes plaster marks... |
|
|
Term
what cautions should be had with acetone? what is antiodote? |
|
Definition
|
|
Term
how should acetone be stored? |
|
Definition
17 degrees C, in dark, glass stopper bottles |
|
|
Term
what is the best concentration of alcohol for antispetic |
|
Definition
|
|
Term
|
Definition
|
|
Term
what is the use of alcohols? |
|
Definition
atringent, antiseptic, solvent, astringent, haemostatic, |
|
|
Term
|
Definition
soft corn, hypergranulation, tissue |
|
|
Term
Aluminium acetate Sln comes as what? |
|
Definition
Burrows Sln, 13% aluminium acetate.. |
|
|
Term
aluminium acetate is diluted at 1:3 for what? |
|
Definition
|
|
Term
what concentration is used for hyperaemic stage of erythrema pernio |
|
Definition
|
|
Term
what concentration of aluminium acetate is used for bromidrosis |
|
Definition
|
|
Term
what is return for aluminium acetate? |
|
Definition
|
|
Term
what is a c/i of aluminium acetate? |
|
Definition
|
|
Term
|
Definition
1.post op, daily paint for eythrema pernio, daily for fissurs, protect from plaster or abrasions, nail packing, Hmolle, protection from wart treatments |
|
|
Term
what is the antidote of TBCo? what are C/I |
|
Definition
alcohol. ci= sepsis, weeping wounds |
|
|
Term
|
Definition
soothing, astringent, absorbent, antipuritic, rashes, erythema pernio |
|
|
Term
|
Definition
|
|
Term
what action does camphor have? |
|
Definition
rubefacient, antipuretic, fungicidal, antiseptic, stimulates then numbs nerves |
|
|
Term
describe the use of Carbon monoxide snow... on VP |
|
Definition
1.debride suurounding callous, 2 apply CO2 to lesion 60 secs with mod pressure, wamr foot bath 5 mins, 60% sal acid for 5-7 days. (note if you dont do steps 3 and 4 a blister will form |
|
|
Term
|
Definition
|
|
Term
what are characteristics of coal tar |
|
Definition
black liquid. strong odour,20% coal tar in 70% alcohol |
|
|
Term
what actions does coal tar have? and what is it used for? |
|
Definition
antiseptic, antipuritic, mild rubifacient, used for psoriasis, eczema, open chill blains |
|
|
Term
what are the uses of crystal violet? |
|
Definition
antiseptic against Gram +ve microbes, fungicide (1:1000), astringent, needs to be applied frequently |
|
|
Term
chlorhexidine gluconate.. active against what? |
|
Definition
antispetic, G+ve and G-ve organisms |
|
|
Term
hydrogen peroxide what is its use? |
|
Definition
antispetic esp against anaerobic bacteria, effervesces violently if septic exudate due to aerobic abcteria enzymes....
also a sleansing agent, softener, styptic |
|
|
Term
|
Definition
|
|
Term
what %age is in ferric chloride sln |
|
Definition
13.9% to 16.1% FeCl3, or strong at 60% |
|
|
Term
what is the use of ferric chloride? |
|
Definition
|
|
Term
describe 3 applications and amount of application of FeCl3 |
|
Definition
daily for a week for nail sulci, 2/day for hypergranulation, use a strong soln (60%) no more than 2 times per week for vascular corns |
|
|
Term
what is a C/I of ferric chloride? |
|
Definition
|
|
Term
|
Definition
mixes with H20, glycerin and alcohol |
|
|
Term
|
Definition
keratolytic, 25% lactic acid +25% sal acid for VP - keep dry for several days. return in 7-14 days for review |
|
|
Term
what is the use of Magnesium sulphate? |
|
Definition
relieve foot strain when used in foot baths, pastes to treat onychia, paronychia, infected cavities, and foreign bodies |
|
|
Term
how is magnesium sulphate used? |
|
Definition
as Magnoplasm (magnesium sulphate and glycerol paste) applied 5mm thick under dressing and bandage and replace every 12-24 hours |
|
|
Term
when is magnesium sulphate not used? |
|
Definition
|
|
Term
what is the use of eucalyptus |
|
Definition
analgesic, antiseptic, healing agent, rubifacient |
|
|
Term
what is a problem with chloroxylenol (dettol) |
|
Definition
only active against Gram +ve |
|
|
Term
what is the success rate of toilnaftate? what is it used for? |
|
Definition
|
|
Term
what is tolnaftate commonly called? what is it active against, and not atcive against... |
|
Definition
tinaderm, trichophyton, E floccosum, microsporum not active against candida!!! |
|
|
Term
what is Daktarin Tincture used for? |
|
Definition
|
|
Term
what is the most efective antifungal? what class is it? |
|
Definition
Terbinafine(lamisil cream), Allylamines |
|
|
Term
Miconazole is called what and used for what? |
|
Definition
Called Daktarin, and is imidazole antifungal |
|
|
Term
econazole (ecostatin)is used for what |
|
Definition
|
|
Term
what are 2 oral antifungals? |
|
Definition
terbinafine, itraconazole |
|
|
Term
what were 2 early oral antifungal |
|
Definition
griseofuluin, Ketoconazole |
|
|
Term
describe the length of Rx with oral antifungals... |
|
Definition
|
|
Term
what are side affects or oral antifungals... |
|
Definition
10% experience... GI disturbances, rashes, pruritis, headaches, dizziness
joint and muscle pain.... also may affect liver function |
|
|
Term
|
Definition
a white toxic crystal phenol used as a photgraphic developer, and to treat certain skin dz. penetrates deeply (a caustic) |
|
|
Term
calamine is used for what actions?
what are CI? |
|
Definition
sootjhing, astringent, antipruritic, rashes chill blains
CI = anhydrosis, wounds |
|
|
Term
Ichtammol is used for what purpose? |
|
Definition
mild antispetic, liquifies pus, fissures, applied for subungual breakdown |
|
|
Term
discuss the use of lactic acid in Vp Rx... |
|
Definition
used at 25% concentration with 25% sall acid, keep dry 7 days and return in 1-2 weeks |
|
|
Term
what is methyl salicylate used as |
|
Definition
powerful rubifactient, and analgesic |
|
|
Term
what are hard parrafins used for> |
|
Definition
used in ointment bases to increase melting points |
|
|
Term
what are liquid paraffin used for/ |
|
Definition
poor emollient, used as a vehicle for other meds, and in ointment and cream bases |
|
|
Term
Discuss the use of Potassium hydroxide in rx of VP |
|
Definition
debride callous, soak foot in warm water 5 mins, dry foot and rub in pellet, immerse foot in water for 2 mins, and dry. debride jelly like VP material. apply Glacial acetic acid to neutralize. return review in 3-7 days |
|
|
Term
what % is sal acic used for a O/P, return? |
|
Definition
|
|
Term
I wish to used sal acid for itsn fungicidal properties... what % useA? |
|
Definition
|
|
Term
Sal acid appears a good choice for a HD on PMA 3, what % to use and when is the return? |
|
Definition
20-40%. return in a min 4-7 days and a max 3 weeks |
|
|
Term
what % is phenol used at? what is its use and what is its antidote? |
|
Definition
80%, nail surgery, glycerin!!! |
|
|
Term
is sal acid a protein precipitant of hydrolyses... (what does this mean? |
|
Definition
hydrolyses, it softens skin! |
|
|
Term
|
Definition
clotrimazole, econazole, miconazole |
|
|
Term
disdcuss silver nitrate use on a Hmole |
|
Definition
|
|
Term
when is caustic therapy contraindicated? |
|
Definition
open wounds, infection and 'at risk feet' |
|
|
Term
in caustic therapy, what is used to mask healthy tissue/ |
|
Definition
|
|