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PATH 1 TEST 2
41
Other
Post-Graduate
09/17/2012

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Term
Process by which blood flow is stopped (process of clot formation)
Definition
Hemostasis
Term
Heme
Definition
Blood
Term
Stasis
Definition
Stopped or slowed
Term
Clot which obstructs flow of blood through the circulatory system?
Definition
Thrombosis
Term
Increased platelet function or Increased clotting activity are?
Definition
Two types of hypercoagulablity
Term
These things cause an increase in clotting factors?
Definition
Acquired Disorders (secondary)
Term
Defects in genes that produce clotting mediators
Definition
Inherited disorders (primary)
Term
Associated with conditons that produce turbulent flow and platelet adherence?
Definition
Arterial thrombi
Term
Associated with conditions that cause stasis of blood with increased concentrations of coagulation factors?
Definition
Venous thrombi
Term
Bleeding
Definition
Hemorrhage
Term
Bleeding disorders are associated with:
Definition

Platelets

Coagulation factors (or lack of)

vessels intergity (weak vessels)

Term
Pin head size bleeding sites in the skin?
Definition
Petechiae
Term
What causes petechiae?
Definition
Very low platelet count
Term
Purpura
Definition
Collection of petechiae (larger spots are ecchymoses)
Term
Abnormally small number of platelet circulatory blood?
Definition
Thrombocytopenia
Term

True or False

 

Blood stored for more then 24 hours has no viable platelets?

Definition
True
Term
Aplastic Anemia
Definition
Bone marrow doesn't produce new cells to replenish
Term
Cancer of the blood or bone marrow
Definition
Leukemia
Term
HIV supresses this?
Definition
production of megakaryocytes
Term
Radiation therapy depresses this?
Definition
Bone marrow function
Term
Spleen normally holds % of platelets before released into blood?
Definition
30-40%
Term
Enlarged Spleen holds this % of platelets?
Definition
80%
Term
Anti platelet antibodies attacking the platelets (blood transfusion or pregnacy)
Definition
Immune Destruction
Term
Narrow blood vessels damaging the platelets?
Definition
Non Immune Mechanisms
Term
This alters platelets so that they cannot agggregate
Definition
Aspirin
Term
Bleeding disorder prevents blood from forming effective clot?
Definition
Hemoplilia
Term
This is a clotting factor?
Definition
13
Term
Deficinency of red blood cells and or hemoglobin
Definition
Anemia
Term
Three classes of anemia:
Definition

Excessive blood loss (hemmorhage or chronic loss)

Excessive blood cell destruction

Deficicent red blood cell production

Term
What is the most common cause of deficient red blood cell production
Definition
Iron deficiency
Term
This is an inherited genetic disorder of red blood cells, hemoglobin is different from the ususal type?
Definition
Sickle Cell Anemia
Term
This is the most common type of anemia
Definition
Iron Deficiency Anemia
Term
Does the body store iron?
Definition
Yes the body will store iron for later use in bone marrow, liver or spleen
Term
Three things that can cause iron deficiency
Definition

Dietary deficiency (diet, sendentarism)

Loss of Iron through bleeding (menstration)

Increased demands (hormones, puberty, growth)

Term
Persistant eating of non nutritive substances (pain, soil,insects, etc)
Definition
Pica
Term
RBC are abnormally large and oval immature nuclei, weak membranes?
Definition
Megablastic anemia
Term
Where is folic acis found?
Definition
Leafy green vegetables, same role in DNA synthesis and RBC formation
Term
Folic acid is linked to neural tube defects?
Definition
Spina bilfida
Term
This is a condition where bone marrow is reduced replacing with non functional tissue (fat)?
Definition
Aplastic Anemia
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