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Mammography
Chapter 8
85
Medical
Post-Graduate
04/12/2016

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Cards

Term
What are the main challenges for mammographic equipment.
Definition

1. Increased contrast sensitivity

2. Reduced dose

3. High spatial resolution (for microcalcifications)

Term
Focal spot sizes used in mammo
Definition
0.3 mm (contact) and 0.1 mm (mag mode)
Term
Typical tube currents in mammo
Definition

100 mA for the 0.3 mm focal spot

25 mA for the 0.1 mm focal spot

200 mA and 50 mA for a W anode.

Term
Common anode targets in mammo
Definition

Molybdenum, Mo

Rhodeum, Rh

Tungsten, W

Term
What is the advantage of a Tungsten anode over Mo and Rh.
Definition
Tungsten has a higher melting point, so higher tube currents can be used.  Also, increased x-ray production efficiency due to its higher atomic number.
Term
Characteristic X-rays for Mo
Definition
17.5 and 19.6 keV
Term
Characteristic X-rays for Rh
Definition
20.2 and 22.7 keV
Term
Typical source to image receptor distance (SID).
Definition
65 cm
Term
Effective Anode Angle, define it and give a value.  Why is it this value.
Definition
Actual anode angle plus the physical tube tilt, 20-24 degrees.  This large angle gives full coverage over the large FOV.
Term

Where are the cathode and anode sides located and why?

 

Definition

Cathode side is over the chest wall.  Anode side is over the nipple.  Why - because of the heel effect.

 

Term
Large field of view (FOV) is what size?
Definition
24 x 30 cm
Term
Describe "half-field" X-ray beam geometry.
Definition
Only half the potential "beam" is used, the other half is collimated out, so the central axis of the beam runs along the chest wall edge perpendicular to the detector. This eliminates unnecessary dose to the patient torso.
Term
Where is the nominal focal spot measured?
Definition
Along the reference axis, which bisects the x-ray field in the A-C direction.
Term
In which direction does the projected focal spot size change in the x-ray field?  How does it change?
Definition
Along the A-C axis.  It is largest at the cathode side (posterior, chest wall) and smallest at the anode side (anterior, nipple).
Term
Where do you get the best resolution and why?
Definition
On the anode side over the nipple because of the smaller projected focal spot size.
Term
Overall system resolution is measured using
Definition
a bar phantom with up to 20 lp/mm
Term
Where is the bar pattern placed?
Definition
4.5 cm above the breast support surface near the chest wall.
Term
What typically limits the system resolution?
Definition
In magnification mammo - the focal spot size, in contact mammo - the detector element size.
Term
What is the tube port window made of?  What is it's atomic number?
Definition
beryllium, Z = 4
Term
Good mammo filters have k-edge energies between __ and __ keV.  Elements that have this include.
Definition
20 and 27 keV.  Mo, Rh and Ag.
Term
What is the purpose of the k-edge filter.
Definition
To remove low energies that result in patient dose and also to remove high energies that don't result in good contrast.
Term
Using a filter that is the same material as the anode allows for what?
Definition
The characteristic x-rays to pass through.
Term
A __ filter should never be used with a Rh target.  Why
Definition
Mo. The Rh characteristic x-rays are above the Mo k-edge so they would be significantly attenuated.
Term
Typical HVL of a mammo x-ray beam.
Definition
0.3 to 0.7 mm Al.
Term
HVL for breast tissue.
Definition
1 to 3 cm.
Term
Minimum HVL limits are set by?  Maximum HVL limits are recommended by?
Definition
minimum - MQSA regulations, maxiumum - ACR accreditation guidelines.
Term
Tube output rate is measured using what mAs?
Definition
300 mAs for an exposure time > 3 seconds
Term
MQSA regulations require a minimum air kerma rate of _______ for screen film detectors.
Definition
7.0 mGy/s
Term
The x-ray field must extend to the chest wall without cutoff, but not beyond the receptor by more than ______?
Definition
2% of the SID
Term
The light field and x-ray field must be congruent to within __________.
Definition
2% overall
Term
MQSA regulations require repairs for light/x-ray field congruence, image receptor alignment, or compression paddle alignment be made within _______ days.
Definition
30
Term
Exposure duration is typically controlled by ____________.
Definition
AEC - Automatic Exposure Control
Term
AEC is set to terminate the exposure based on
Definition
a specified signal-to-noise ratio
Term
What are the 3 modes of operation that the AEC can have?
Definition
1) fully automatic kV and filtration, 2) automatic kV, user set filtration, 3) user set kV and filtration
Term
A _______ is used if the exposure is not terminated by the AEC.
Definition
backup timer
Term
How much can the AEC can be modified by the user?
Definition
There are 5 steps down and 5 steps up.  Each changes the exposure by 10-15%.
Term
Phototimer positioning can usually be adjusted in what direction.
Definition
Chest wall to anterior.
Term
Typical exposure times in mammo.
Definition
0.5 to 2.0 secs
Term

Regarding artifacts,

Too short of an exposure can result in _________.

Too long of an exposure can result in _________.

Definition

too short - grid lines

too long - patient motion

Term
Advantages of breast compression.
Definition
Reduces overlapping anatomy, reduces motion, less scattered x-rays and lower radiation dose.
Term
Typical compression force.
Definition
25 to 44 lbs.
Term
Contrast Degradation Factor
Definition
CDF = Cs/Co (contrast with scatter / contrast without scatter) = 1 / (1 + SPR)
Term
Scatter depends mostly on _____ and _____.
Definition

breast thickness and field size.

Note: Its not really a function of kV because there is such a small range of kV used in mammo.

Term
How is scatter reduced in mammography?
Definition
Antiscatter grid or an air gap.
Term
Typical grid ratios in mammography.
Definition
4 to 5
Term
Bucky factor of a mammo grid.
Definition
2 to 3
Term
What are the consequences of using an air gap to reduce scatter.
Definition
Smaller FOV, increased magnification, and increased dose to the breast.
Term
Magnification in mammo is typically used for
Definition
better visualization of microcalcifications.
Term
Mag mode causes _________ dose to the breast.
Definition
about the same.  The grid is removed which means less dose, but the breast is closer to the x-ray source which means more dose.  The two effects basically cancel each other out.
Term
Downsides to magnification.
Definition
Increased geometric blurring.  Reduced tube current means longer exposure times which can lead to patient motion blurring.
Term
Upsides to magnification.
Definition
Increased effective resolution, reduced image noise, and a reduction in scattered radiation.
Term
Biggest advantage of digital mammography.
Definition
It doesn't have the exposure latitude limitations of screen-film detectors.
Term
Each detector element in a flat panel array consists of what 3 things?
Definition
An electronic switch (the TFT), a charge collection electrode, and a storage capacitor.
Term
What is common to all flat panel TFT arrays?
Definition
An amorphous silicon circuit layer.
Term
An indirect detection TFT flat panel array has what on top of the amorphous silicon layer?
Definition
A CsI phosphor to convert x-rays to light and photodiodes to convert light to electrical charge.
Term
A direct detection TFT flat planel array has what above the amorphous silicon circuit layer.
Definition
A layer of Amorphous selenium located between two electrodes.  The x-rays create electron-hole pairs in the selenium.  A voltage across the electrodes causes the electrons to move.
Term
Which detector results in the lowest average glandular dose?  The highest?
Definition
Lowest - indirect TFT detectors, Highest - cassette-based CR detectors.
Term
What is a typical pixel size in digital mammo?
Definition
0.05 mm to 0.1 mm
Term
The "For Processing" image has ______ latitude and _____ contrast.
Definition
wide latitude and low contrast.
Term
The "For Presentation" image has _______ and _______ _________ enchancements.
Definition
contrast and spatial resolution
Term
The interpretation monitor should have a minimum of ______ pixels.
Definition
5 millon
Term
The maximal luminance should be at least _______ cd/m2 per ACR guidelines but preferably ________ cd/m2.
Definition
at least 450, preferably 600 cd/m2
Term
Computer Aided Detection (CAD) systems use the _____________ images.
Definition
"For Processing"
Term
Stereotactic breast biopsy are generally used to target
Definition
microcalcifications
Term
In stereotactic breast biopsy, two images are acquired at ______ degrees.
Definition
+15 and -15
Term
What is the size of the image detector in stereotactic breast biopsy; FOV, size of the detector array and size of the detector element.
Definition
5x5 cm2 FOV, 1000x1000 detector element matrix with each element 0.05 mm.
Term
In Stereotatic Breast Biopsy, the lesion distance from the detector is given by
Definition
Zdetector to lesion = shift (mm) / (2 tan(15°))
Term
Breast tomosynthesis involves acquiring ___ to ____ images over _____ degrees up to _____ degrees.
Definition
15 to 40 images over ±7.5 degrees up to ±30 degrees
Term
Primary advantage of breast tomosynthesis.
Definition
It reduces the overlying and underlying anatomy.
Term
Average glandular dose from breast tomosynthesis?
Definition
≈ 2 mGy
Term
Why is average glandular dose the prefered dose index in mammography?
Definition
The glandular tissue is the site of the carcinogenesis.
Term
What is the equation for average glandular dose?
Definition

Dg = DgN x XESAK

XESAK - entrance skin air kerma

DgN - air kerma to avg. glandular dose conversion factor

Term
The conversion factor DgN depends on
Definition
radiation quality (kV and HVL), x-ray tube target material, filter material, breast thickness and tissue composition.
Term
Typical values for the conversion factor DgN.
Definition

0.17 to 0.20

(mGy of AGD per mGy incident air kerma)

Term
What is the thickness of the accreditation phantom?
Definition
4.5 cm
Term
The MQSA regulations limit the average glandular dose for a compressed breast of 4.2 cm thickness and a 50% glandular / 50% adipose tissue to ______.
Definition
3 mGy per digital image
Term
Typical dose per view for a full field digital mammo system.
Definition
1.2 to 1.8 mGy per view.
Term
For a facility to legally perform mammo under MQSA, it must be both _________ and _______.  Explain.
Definition

Accredited and Certified

Accredited by an accreditation body like the ACR that it meets MQSA standards.

Certification is the approval of the facility by the FDA.

Term
What is the accreditation phantom intended to mimic?
Definition
A standard breast of 4.2 cm compressed breast thickness of 50% adipose and 50% glandular tissue composition.
Term
What is in the wax insert in the mammo phantom?
Definition
There are 6 nylon fibers, 5 calcification groups and 5 low contrast disks (masses).
Term
What is required to pass MQSA image quality standards when viewing the phantom.
Definition
You must see at least 4 fibers, 3 calcification groups and 3 masses at an average glandular dose of less than 3 mGy
Term
What are the main differences between a mammo system and a general radiographic system.
Definition
1. shorter SID, 2. lower tube voltages, 3. smaller focal spots, 4. specialized targets and filters, 4. half field geometry, 5. tilted x-ray tube, 6. compression paddle, 7. magnification stands, 8. AEC after (not before) the image receptor
Term
How is image reconstruction performed in tomosynthesis?
Definition
The images are shifted to the selected plane and then added to create the tomograms.
Term
What does MQSA stand for?  Where is it defined?
Definition

Mammography Quality Standards Act

21 CFR 900.12

Term
What are the daily and weekly QC tests?
Definition

Daily - uniformity and artifact evaluation

Weekly - phantom image evaluation

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