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Male Gonadal Tumors
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7
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06/16/2006

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Term
What % of testicular tumors are germ cell?
Definition
Half or more of germ-cell tumors of the testis have nonseminomatous histology.
Term
What is treatment of Germ Cell tumors
Definition
Chemotherapy is the treatment of choice.
Term
Prognosis for germ cell tumors?
Definition
Prognosis is excellent, even in advanced stage disease.
Term
What are the types of germ cell test. tumors?
Definition
The nonseminomatous germ-cell tumors are embryonal carcinoma, teratoma, yolk sac tumor, choriocarcinoma, and the mixed germ-cell tumor.
Term
US appearance of Seminoma
Definition
Seminomas are usually uniformly hypoechoic, whereas the nonseminomatous tumors are typically heterogeneous in appearance.
Term
Metastatic route for Germ cell tumors of testicle? How is chorio different?
Definition
The majority of germ-cell tumors metastasize via the lymphatic system to the retroperitoneal lymph nodes first. Choriocarcinoma, however, spreads hematogenously early in its progression. If there is a high suspicion for brain metastases at presentation, such as with choriocarcinoma, imaging of the brain would be indicated.
Term
What serum tumor markers play a role in management and diagnosis?
Definition
AFP, HCG, and LD
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