Term
Consists of two semi-independent parts |
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Definition
Lymphatic vessels, lymphoid tissues and organs |
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Term
What are the lymphatic system functions? |
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Definition
Transports escaped fluids back to the blood Plays essential roles in body defense and resistance to disease |
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Term
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Definition
Excess tissue fluid carried by lymphatic vessels |
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Term
What are properties of the lymphatic vessels? |
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Definition
One way system toward the heart No pump Lymph moves toward the heart |
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Term
What are properties of the lymphatic vessels? |
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Definition
Walls overlap to form flap-like minivalves Fluid leaks into lymph capillaries Fluid is forced along the vessel |
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Term
What is the process of the lymphatic vessels? |
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Definition
Collect lymph from lymph capillaries Carry lymph to and away from lymph nodes Return fluid to circulatory veins near the heart |
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Term
What are harmful materials that enter lymph vessels? |
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Definition
Bacteria Viruses Cancer Cells Cell Debris |
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Term
What is the function of the lymph nodes? |
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Definition
Filter lymph before it is returned to the blood |
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Term
What do the lymph nodes use to filter the lymph? |
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Definition
Defense cells within lymph nodes macrophages-engulf and destroy foreign substances Lymphocytes-provide immune response to antigens |
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Term
What is the flow of lymph through nodes? |
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Definition
Lymph enters the convex side through afferent vessels flows through a number of sinuses Lymph exits through efferent vessels Fewer efferent than afferent causes flow to be slowed |
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Term
What other organs contribute to lymphatic function? |
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Definition
Spleen Thymus Tonsils Peyer's Patch |
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Term
Where is the spleen located? |
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Definition
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Term
What is the function of the spleen? |
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Definition
Filters blood, destroys worn out blood cells |
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Term
Where is the Thymus Gland located? |
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Definition
Low in the throat, overlying the heart |
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Term
What is the function of the thymus gland? |
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Definition
Produces hormones like thymosin to program lymphocytes, functions peak levels only during childhood |
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Term
Where are the tonsils located? |
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Definition
In small masses of lymphoid tissue around the pharynx |
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Term
What is the function of the tonsils? |
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Definition
Trap and remove bacteria and other foreign materials |
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Term
What are Peyer's Patches located? |
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Definition
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Term
What is the function of Peyer's Patch? |
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Definition
Capture and destroy bacteria in the intestine |
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Term
What is the purpose of Mucosa-Associated Lymphatic Tissue (MALT)? |
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Definition
As as a sentinel to protect respiratory and digestive tracts |
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Term
What are the two different defense system our bodies have for foreign materials? |
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Definition
Innate (nonspecific) Adaptive (Specific) |
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Term
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Definition
Specific resistance to disease |
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Term
Protect against a variety of invaders Responds immediately to protect body from foreign materials |
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Definition
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Term
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Definition
specific defense is required for each type of invader |
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Term
What are innate body defenses? |
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Definition
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Term
What are some examples of innate body defenses? |
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Definition
Intact Skin Mucous membranes Specialized human cells Chemicals produced by the body |
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Term
Physical barrier to foreign materials Provides protective secretions |
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Definition
Skin and mucous membranes |
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Term
secretes hydrochloric acid has protein-digesting enzymes |
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Definition
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Term
Natural killer cells Inflammatory response Phagocytes Antimicrobial proteins Fever |
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Definition
Defense system cells and chemicals: Second Line of Defense |
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Term
Natural Killer (NK) Cells |
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Definition
disintegrate kill cancer cells can destroy virus infected cells |
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Term
What triggers and inflammatory response? |
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Definition
When body tissues are injured |
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Term
Four most common indicators of acute inflammation |
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Definition
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Term
What are the functions of the inflammatory response? |
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Definition
Prevents spread of damaging agents disposes of cell debris and pathogens through phagocytes sets the stage for repair |
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Term
What is the process of the inflammatory response? |
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Definition
Neutrophils migrate to the area squeeze through capillary walls by diapedesis gather in the precise site of tissue injury and consume any foreign material present |
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Term
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Definition
Neutrophils and macrophages, engulf foreign materials and lysosomes digest |
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Term
Monocytes become macrophages and complete disposal of cell debris |
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Definition
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Term
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Definition
Activated when they encounter and attach to cells, damage foreign cell surfaces |
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Term
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Definition
Proteins secreted by virus-infested cells, bind to healthy cell surface to interfere with the ability of viruses to multiply |
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Term
What is responses to a fever? |
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Definition
hypothamlamus, fever also increases the speed of tissue repair |
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Term
What are the three aspects of adaptive defense |
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Definition
antigen specific, systemic, memory |
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Term
What are the types of immunity? |
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Definition
Humoral Cellular Antigens Allergies |
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Term
What is humoral immunity? |
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Definition
antibody-mediated immunity, provided by antibodies present in body fluids |
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Term
What is cellular immunity? |
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Definition
cell-mediated immunity, targets virus-infected cells, cancer cells, and cells of foreign grafts |
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Term
What are examples of common antigens? |
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Definition
Foreign proteins nucleic acids large carbohydrates lipids pollen microogranisms |
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Term
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Definition
Small molecules-haptens may recognize and respond immune response is harmful rather than protective because it attacks our own cells |
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Term
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Definition
Originate from hemocytoblasts in the red bone marrow |
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Term
Where do b lymphocytes become immunocompetent? |
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Definition
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Term
Where do T lymphocytes become immunocompetent? |
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Definition
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Term
What does Macrophages secrete? |
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Definition
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Term
What type of lymphocytes respond to a Humoral Immune Response? |
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Definition
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Term
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Definition
A second exposure causes a rapid response, the secondary response is stronger and longer lasting |
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Term
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Definition
Naturally acquired during bacterial and viral infections artificially acquired from vaccines |
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Term
What is passive immunity? |
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Definition
Antibodies obtained from someone else, a mother to her fetus, immune serum or gammma globulin |
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Term
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Definition
Soluble proteins secreted by B cells |
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Term
What are the five major immunoglobulin classes? |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
important in activation of B cell |
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Term
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Definition
Can cross the placental barrier and fix complement |
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Term
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Definition
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Term
Cell-Mediated Immune Response |
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Definition
Cytotoxic (killer) T cells Specialize in killing infected cells Helper T cells Recruit other cells to fight the invaders |
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Term
What are the major types of grafts? |
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Definition
Autografts Isografts Allografts Xenografts |
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Term
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Definition
tissue transplanted from one site to another on the same person |
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Term
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Definition
Tissue grafts from an identical person |
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Term
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Definition
Tissue take from an unrelated person |
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Term
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Definition
Tissue taken from a different animal species |
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Term
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Definition
Immediate hypersensitivity Delayed hypersensitivity |
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Term
Triggered by release of histamine from IgE binding to mast cells, anaphylactic shock |
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Definition
Immediate hypersensitivity |
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Term
Triggered by the release of lymphokines from activated helper T cells Symptoms appear 1-3 days later |
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Definition
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Term
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Definition
white matter of brain and spinal cord are destroyed |
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Term
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Definition
impairs communication between nerves and skeletal muscles |
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Term
Destroys pancreatic beta cells that produce insulin |
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Definition
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Term
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Definition
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Term
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Definition
Impairment of renal function |
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Term
Except for thymus and spleen, the lymphoid organs are poorly developed before birth |
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Definition
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