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Lymphatic System
Lecture 4 Part 2
107
Pathology
Graduate
06/23/2014

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Cards

Term
Functions of the Lymphatic System: 1
Definition
maintain fluid balance in the tissues
Term
Functions of the Lymphatic System: 2
Definition
fight infection
Term
Functions of the Lymphatic System: 3
Definition
assist in the removal of cellular debris and waste products from the extracellular spaces within tissues
Term
Normal Lymphatic Functioning: 1
Definition
fluid that leaves the arteriole and capillaries nourishes the tissues and cells
Term
Normal Lymphatic Functioning: 2
Definition
Approximately 90% of this tissue fluid volume reenters the circulation via the venous capillary network
Term
Normal Lymphatic Functioning: 3
Definition
Remaining 10% of this extra-cellular fluid and plasma proteins is returned to the heart via the lymphatic system
Term
If this normal tranpsort system is disrupted, significant accumulations of water and plasma proteins can remain in the tissue spaces and result in
Definition
lymphedema
Term
One way vessel system that serves to drain the 10% tissue fluid volume and plasma proteins that remain in the interstitila space after the normla perfusion takes palce
Definition
lymphatic vessels
Term
The smallest of lymphatic vessels
Definition
lymphatic capillaries
Term
Where are lymphatic capillaries found?
Definition
close to venous and arterial capillaries
Term
GLands that play an important part in the body's defense against infection?
Definition
lymph nodes
Term
Travels through the body and filters impurities from the body
Definition
lymph
Term
Trap and filter foreign particles
Definition
lymph nodes
Term
Approximately how many lymph nodes exist within the body?
Definition
~600
Term
How many lyph nodes are in the head?
Definition
300
Term
Inguinal, axillary, supraclavicular, cervical, behind teh ears, and occiptal are locations for what
Definition
palpable superficial lymph nodes
Term
How can lymph nodes become enlarged?
Definition
infection, tumor
Term
Why do lymph nodes become enlarged primarily
Definition
elevated rate of trafficking of lymphocytes into the node from the blood, exceed the rate of outflow from the node
Term
Why do lymph nodes become activated secondarily?
Definition
activation and proliferation of antigen-specific T and B cells
Term
What are lymphotomes
Definition
lymph drainage territotires
Term
Where does the Left thoracic lymphotome drain into?
Definition
L axilla and upper extremity
Term
Where does the right thoracic lymphotome drain into?
Definition
right axilla and upper extremity
Term
WHere does the left abdominal lymphotome drain into?
Definition
L inguinal nodes, thoracic duct, left subclavian vein. L eg, lumbar, gluteal, genital regions
Term
Where does the Right abdominal lymphotomes drain into?
Definition
R inguinal nodes, thoracic duct, and L subclavian vein. R leg, lumbar, gluteal, genital regions
Term
The right upper extremity, R side of the head and neck, heart and lungs drain into the ___ lymphatic duct
Definition
R
Term
THe L UE, thoracic lymphotome, both LE's, both abdominal lymphotomes, and external genital regions drain into the ___ subclavian vein via the ____ duct
Definition
L, thoracic
Term
PT and lymphatic system
Definition
identification of suspicious, palpable nodes ina patient with h/o of CA
Term
PT and identifying suspicious, palpable nodes
Definition
consider referring back to the physician
Term
Which nodes are common sites for metastatic cancer?
Definition
inguinal, supraclavicular
Term
What is lymph fluid?
Definition
colorlles fluid containing oxygen, proteins, glucose, lymphocytes
Term
WHat occurs when the lymph transport capacity is inadequate to transport the normal volume of lymph?
Definition
low flow edema
Term
WHat is characterized by swellign of soft tissues, usually in the extremities, due to accumulation of lymphatic fluid in the extracellular spaces
Definition
lymphedema
Term
Primary Lymphedema
Definition
occurs idiopathically
Term
Secondary Lymphedema
Definition
Occurs after disruption or damage to the lymphatic system
Term
Pitting edema
Definition
'pit' remains in affected extremity after contact is made
Term
Lymphedema: Stage 1
Definition
soft, pitting edma which will diminish with elevation
Term
How does Stage 1 lymphedema occur?
Definition
accumulation of proteins in the interstitial space
Term
Stage 2 Lymphedema
Definition
non-pitting, does not reduce with elevation, mild fibrosis of teh tissue. Eczema, warts, papillomas may develop
Term
How does stage 2 lymphedema occur?
Definition
as chronic inflammatory response mounts
Term
Stage 3 lymphedema
Definition
severe, non pitting fibrotic edema with skin changes such as thickened, leathery keratotic skin
Term
Primary Lymphedema etiology
Definition
associated with malformation of lymphatic vessels
Term
Malformations of the lymphatic vessels
Definition
aplastic, hypoplatic, hyperplastic
Term
aplastic vessels
Definition
lymphatic collectors can be absent
Term
hypoplastic vessels
Definition
too few in number
Term
hyperplastic
Definition
enlarged, dilated, varicose collectors
Term
Which lymphedema may be inherited?
Definition
primary
Term
Secondary Lymphedema etiology
Definition
damage to or obstruction to an otherwise normal strcuture
Term
Causes for secondary lymphedema: 1
Definition
invasive procedures used in the diagnosis and treatment of cancer
Term
Causes for secondary lymphedema: 2
Definition
bacterial, viral infections
Term
Causes for secondary lymphedema: 3
Definition
chronic venous insufficiency
Term
Causes for secondary lymphedema: 4
Definition
multiple abdominal surgeries
Term
Causes for secondary lymphedema: 5
Definition
surgeries/traufa that interfere with normal lymphatic flow
Term
Lipedema
Definition
painful fat syndrome
Term
Differences between lipedema and lymphedema
Definition
does it affect the feet too?
Term
Lymphedema, basic cause?
Definition
transport capacity is greater the the volume of the lymph
Term
Lymphedema pathophysiology: 1
Definition
transport capacity can be diminished causing decreased absorption of lymph in the lymph nodes
Term
Lymphedema pathophysiology: 2
Definition
volume of lymph is greater than normal
Term
Lymphedema pathophysiology: 3
Definition
10% tissue volume that is not transported by the venous system has no alternative transport pathway except for lymphatics
Term
Lymphedema pathophysiology: 4
Definition
if lymphatic transport is impaired, a back up of lymphatic fluid develops
Term
Lymphedema causes _____ of the lymphatic vessels
Definition
dilation
Term
Dilation of the lymphatic results in waht?
Definition
incompetence of the valves resulting in reflux of lymphatic fluid into tissue spaces
Term
THe body attempts to compesnate with lymphedema by creating what?
Definition
initial lymphatic vessels
Term
Formation of collateral vessels (called collateralization) is the body's way of trying to ____ the lymphedema
Definition
drain
Term
Chronic inflammation at this lymphedematous tissue now casues fibrosis which leads to
Definition
hypxoia, continuation of inflammation, increased risk of infection and delayed wound healing
Term
Cellultis
Definition
infection of the tissues
Term
lymphangitis
Definition
infection in the lymph vessels
Term
lymphangiosclerosis
Definition
tissue fibrosis and scarring
Term
Gas exchange and metabolism remians impaired despite attempts at
Definition
collateralization
Term
Lack of _____ and ____ leads to inefficiency of macrophages
Definition
oxygen, nutrients
Term
Lymph pump becomes ineffective due to the _____ of the muscle wall within the lymphatics
Definition
hypertrophy
Term
Potential complications with chronic lymphedema: 1
Definition
infection
Term
Potential complications with chronic lymphedema: 2
Definition
circulatory compromise
Term
Potential complications with chronic lymphedema: 3
Definition
gait disturbances
Term
Potential complications with chronic lymphedema: 4
Definition
loss of strength in involved area
Term
Potential complications with chronic lymphedema: 5
Definition
pressure sores
Term
Potential complications with chronic lymphedema: 6
Definition
enteropathy
Term
enteropathy
Definition
involvement of teh intestines
Term
S/S of lymphedema: 1
Definition
fullness of the affected body part
Term
S/S of lymphedema: 2
Definition
sensation of skin tightness
Term
S/S of lymphedema: 3
Definition
decreased flexibility
Term
S/S of lymphedema: 4
Definition
difficulty with dressing the involved limb
Term
Lymphedema physical impairments: 1
Definition
increased circumferential girth
Term
Lymphedema physical impairments: 2
Definition
postural changes
Term
Lymphedema physical impairments: 3
Definition
neuromuscular deficits (ie weakness)
Term
Lymphedema physical impairments: 4
Definition
integumentary complications due to hypoxia
Term
integumentary complicatoins
Definition
loss of hair and sweat glands, formation of keratotic patches, formation of blisters on the skin
Term
Lymphedema physical impairments: 5
Definition
depression due to dysmorphia
Term
Major caution with lymphedema
Definition
healing time is dealyed. clumsy enlarged limbs at greater risk for injury
Term
Comprehensive Lymphedema Management
Definition
CLM
Term
CLM: 1
Definition
manual lymphatic drainage
Term
manual lymphatic drainage
Definition
gentle massge done to increase circulation
Term
CLM: 2
Definition
short stretch compression bandaging, exerts minimal pressure on the limb
Term
CLM: 3
Definition
exercise
Term
CLM: Exercise
Definition
mimics pumping effect of muscles to increase lymph flow
Term
CLM: 4
Definition
compression garments
Term
CLM: compression garments
Definition
design to maintain decrease of lymphedema
Term
CLM: education
Definition
pathophysiology, treatment rationale, compliance of home program, proper self care
Term
CLM: self care
Definition
skin care, preventing lymph overload, self massage, bandaging, lifestyle modification
Term
IPC pumps can be applied to the edematous limb and can help to reduce early stage 1 lymphedema
Definition
compressing pumps
Term
Compression pumps can be used with what stage lymphedema?
Definition
early 1
Term
Lymphedema and the PT: PT EValuation: 1
Definition
patient education
Term
Lymphedema and the PT: PT EValuation: 2
Definition
avoid affected extremity with measuring BP
Term
Why is it important to avoid the affected extremity with measuring BP?
Definition
pressure of the inflated cuff could damage lymphatic vessel walls
Term
Lymphedema and the PT: PT EValuation: 3
Definition
Record detailed description of skin integrity, color, texture, presence of fibrotic or keratotic areas)
Term
Lymphedema and the PT: PT EValuation: 4
Definition
include photos if possible to monitor progress and efficacy of treatment
Term
Lymphedema and the PT: PT EValuation: 5
Definition
include accurate volumetric/girth measures bilaterally
Term
Lymphedema and goals for interventions
Definition
functional impairments
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