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4 main functions of Lymphatic system |
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Fluid Recovery, Immunity, Lipid absorption, and Transportation. |
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Recovers 2-4 Liters of fluid not reabsorbed back into the capillaries and 1/4 protiens. |
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Surviellence and defense, filters out blood lymph for pathogens, cancer cells, and other foreign substances. |
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Lipids absorbed by lacteals in the intestinal vili. Stomach breaks everything down and lacteals absorb fats. |
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Lympocyte highway, also transports hormones, some nutrients, waste products, pathogens, metastic caner cells. |
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lymphatic vessels that absorb lipids due to the structure of lipids. Structure=long chain of fatty acids and ditriglycerides that can't be absorbed by small intestinal capillaries |
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Clear, colorless (milky white in lacteals). Originates as ISF surrounding capillaries so it's similar to plasma. Contains fluid, metastatic tumor cells, hormones, pathogens, WBC. |
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Interspersed with blood capillaries in the capillary bed. Excess fluid and some solutes from capillary filtration are recovered by lymphatic capillaries. Your bodies "storm drain" system. |
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Dead end tubes-more permeable than blood capillaries. Shingle arrangement of endothelial cells. Anchoring filaments that pull cells apart when fluid increases. increased pressure in the IF PUSHES the flaps open, letting fld into the lymph capillaries |
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If your lymphatic system does not work properly you may get edema |
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Presented in tissues only. Not in CN system b/c CN NS has CSF. Also not presented in bone marrow, teeth, epidermis, cartilage, and cornea. |
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Lymphatic capillaries drain into larger lymphatic vessels-then Lymphatic trunks-then lymphatic ducts- *Right lymphatic duct and thoracic duct and finally subclavian veins. |
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lymphatic sac in lower thorax that drains interstinal lymph and is filled with chyle. |
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Drains the right head and neck, the righ upper extremity and the right thoracic cavity. HAT-head, right arm, thorax. |
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all other lymph drain here. Left head, L-abdomen, R & L legs. |
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Rhythmic contrations of lumph vessels, lymph fluid stretches lymph vessel, automatic contration of smooth muscle in lymphatic vessel wall. Other factors include valves-prevent backflow, skeletal muscle and respiratory pump, arterial pulsation, rapid flowing of blood od subclavian veins. |
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NK cells 5%-T-lymphocytes 80%-B-Cells 15% |
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Roam body looking for pathogens etc… |
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phagocytes derived from monocytes. Function as APC's. alert the specific immune system. |
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Eat bad guys, take part of the bad guy and wear it on ther shirt. Therefore, other cells are activated when they see the bad guy on his shirt. |
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Dendritic cells and B cells. |
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Scattered lymphocytes, MALT-mucous associated LC BALT-Respiratory tract, GALT-digestive tract. |
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Lymph Follicles or Nodules |
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Dense oval shaped, no capsule, lots of lymphocytes, stand alone or appear in clusters, Peyer's Pathes, or inside organs like nodes, tonsils, appendix, and spleen. |
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Lymph node v.s. follicles |
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node is an organ and follicle is a tissue inside an organ/clusters of lymphocytes. |
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Red bone marrow and thymus gland. Cells mature in these organs. |
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Tonsils, lymph nodes (filter lymph) and spleen (filters blood) |
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able to recognize and respond to antigens |
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It is a primary Lymph organ. Red bone marrow contains.. |
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reticular cells, developing blood cells & blood sinusoids. B-bone marow T-Thymus. |
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Primary lymph organ. large at birth and gets smaller as adult. T-cells mature here. |
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Partially encapsulated, Crypts are distinguishing feature (trap)-Located in mucous membranes protecting pharynx |
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Only organs that filter lymph, and they activate immune response. Side note-wbc get in/out of blood vessels easily. |
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imflammation, swelling, & enlargement o nodes. Infected nodes that are tender, enlarged, swollen, and moveable but not firm. |
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firm, enlarged, swollen and firm, not moveable, and appears attached to underlying tissues. |
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Large organ upper left, filters blood, contains a stroma w/ thin capsule (smooth muscle) & Trabeculae (w/ reticular fibers). Parenchyma has white pulp- lymphc & macros surround ingoing arteries (sleeve). Red pulp-leaky sinuses where blood flows slowly. |
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1.Fliter RBC-removes dead/defective RBC & removes pathognes, toxins, and debris. 2. Blood reservior-smooth muscle capsle contracts, splenic volume decreases 40-50% during excerise. 3. Platelet reservior-1/3 blood supply. 4..Produces RBC in fetus. 5. Immune surveillance and lymphocyte proliferation & activation. |
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enlargement of spleen. Inflammed -infectious mono. Congestive-heart failure, portal vein, obstruciton cirrhosis. Infiltrative-tumors and cysts. |
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sergical removal of spleen. |
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Reasons for spleen removal |
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tumors, lymphomas, polycythemia vera-overactive spleen-storing too many WBC or RBC resulting in anemia or leukopenia. And too many platelets resulting in thrombocytopenia. |
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ring worm infection from mosquitto. Infected nodes and block flow of lymph. Results in edema & fibrosis leads to elephant-like thickening of the skin. |
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hodgkin's and non-hodgkins disease |
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Distinctive abnomal chromos in cells of lymph nodes, named after dr. Does not cause pain and people can live w/it for a long time. |
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