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Lupus
PT exam 4
6
Pharmacology
Graduate
03/30/2012
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Term
What is lupus?
 Definition

SLE= systemic lupus erythematosus

Autoimmune disease that affects many body systems

Classified as a collagen-vascular disease

Chronic inflammatory disease

Body produces excessive and abnormal antiantibodies which create immune complexes
Term
What parts are involved in collagen-vascular diseases?
 Definition
Musculoskeletal system, integument, and blood vessels
Term
What causes overproduction of autoantibodies?
 Definition
hyperactive B lymphocytes
Term
What are the signs and symptoms of SLE?
 Definition

Arthritis & arthralgia 
Fatigue, Fever
Photosensitivity, weight loss 
butterfly rash, Raynayd's phenomenon

Discoid lesions, psychosis, renal, pleural effusion

Anemia, leukopenia, thrombocytopenia, lymphadenopathy

CNS system, seizures, pleuritis, myocarditis, pericarditis, heart murmur, nausea, abd pain, bowel hemorrhage
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