Term
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Definition
Dust mites, pet dander, made worse by exercise, stress and pollution |
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Term
What are symptoms of Asthma? |
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Definition
Difficulty breathing, coughing, tight feeling in chest. |
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Term
What happens when an individual has asthma? |
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Definition
Muscles in walls of bronchioles and bronchi contract (size of airway reduced) Goblet cells produce excess mucus Most cells produce histamines so linings become inflamed and blood vessel dilate. air flow restricted-> less air reaching alveoli-> hard to maintain diffusion gradient-> less oxygen in blood. |
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Term
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Definition
prolonged exposure to fine dust particles (mining) |
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Term
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Definition
Shortness of breath, dry cough,pain and tiredness |
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Term
What happens in Fibrosis? |
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Definition
Engulf bacteria and dust macrophages move into connective tissue from alveoli If there is a constant amount of bacteria then machrophage stay in scar tissue which thickens connective tissue, creating slower diffusion rate. Fibrosis tissue also reduces elasticity of aveoli making it harder to ventilate lungs |
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Term
What causes Emphysema and what are the symptoms? |
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Definition
Toxins in cigarette smoking Tiredness and difficulty in breathing |
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Term
What happens in Emphysema? |
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Definition
Toxins in smoke stimulate white blood cells release enzymes, slowly break down walls of alveoli(smaller surface area-> slower diffusion) Enzymes break down elastic fibres (cant breath as effectivly) |
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Term
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Definition
Coughing/sneezing as bacteria transmitted in droplets |
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Term
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Definition
cough, tiredness, coughing up blood |
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Term
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Definition
bacteria multiply and form clumps (tubercles)infected tissue dies destroying alveoli. less exchange surface-> less diffusion Can also lead to fibrosis |
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Term
What is meant by asymptomatic? |
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Definition
when people are infected but don't know as bacteria lies dormant in tubercles. |
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Term
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Definition
Fatty deposit that forms WITHIN an artey wall |
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Term
How does an atheroma lead to myocardial infaction? |
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Definition
They can enlarge to form plaques which bulge into lumen of the artery. causing it to narrow so blood flow is reduced. |
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Term
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Definition
When an atheroma breaks through the lining of blood vessel to form a rough surface which interrupts flow of blood. This can result in a blood clot. |
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Term
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Definition
atheromas that lead to thrombosis also weaken artery wealls. The weakened points swell to form a balloon like blood filled structure. |
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Term
What happens when an aneurysm bursts? |
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Definition
Lead to haemorrhage and therefore loss of blood to the region of the body served by that artery. |
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Term
What is a myocardial infarction? |
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Definition
A heart attack. When a coronary artery is blocked. |
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Term
Why does smoking increase your risk of heart disease? |
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Definition
Carbon monoxide combines with hemoglobin and reduces amount of oxygen transported in blood so heart muscle must work harder. Nicotine stimulate production of adrenaline, inccreases heart rate and raises blood pressure. makes platelets in blood stick-> thrombosis, |
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Term
Why does high blood pressure increase your chance of heart disease? |
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Definition
high pressure in arteries already, heart must work harder to pump blood. Damaged walls have a risk of atheorma or aneuryms.Artery walls become thicker so reduce blood flow. |
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Term
Why does cholesterol increase chance of heart disease? |
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Definition
LDL transport cholesterol from liver to tissue, which they infiltrate leading to atheroma. |
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