Shared Flashcard Set

Details

LUDI Vitamin K
Vitamin Lecture series
16
Dentistry
Undergraduate 2
04/21/2014

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Cards

Term
Forms of vitamin K (2)
Definition
1. K1 Phylloquinone
2. Menaquinone
Term
Required for vitamin K absorbtion
Definition
Bile and pancreatic enzymes
Term
Source of phylloquinone
Definition
Plants. Highest in leafy greens and veg
Term
Can the body store vitamin k (it is fat soluble)
Definition
No
Term
What does the vitamin K1 cycle allow?
Definition
Small amounts of vitamin K1 to be recycled many times
Term
What is the function of vitamin K1
Definition
Maintenance of normal coagulation
Term
What can happen to vit K1 by bacterial flora in the colon
Definition
Conversion to vit k2
Term
Source of menaquinone
Definition
Animal origin. Dairy products and animals that feed on grass.
Term
Can menaquinone (k2) be recycled?
Definition
No
Term
How long does it take for a menaquinone (k2) deficiency to develop?
Definition
7 Days
Term
Vit K physiology
Definition
1. Cofactor for liver microsomal carbozylase
2. Required in the carboxylation of protien precursors providing calcium binding sites needed for functional and biological activity
Term
Vitamin K deficiency causes (3)
Definition
1. Fat malabsorbtion syndromes (e.g. coeliac, chronic pancreatis, chrons disease)
2. Destruction of endogenous vitamin K synthesising flora
3. Liver damage/disease
Term
Phylloquinone (k1) deficiency manifestations
Definition
Development of bleeding diathesis (susceptible to bleeding)
Term
Phylloquinone (K1) deficiency clinical manifestations (3)
Definition
1. Haematomas (collection of blood outside a vessel)
2. Maematuria (blood in urine)
3. Gingival bleeding
Term
Menaquinone (K2) deficiency manifestations (4)
Definition
1. Lack of calcium where needed so bones become porous as bone remodelling removes bone faster than new bone laid
2. Atherosclerosis- excess Ca where it is not needed
3. Dental caries
4. Varicose veins
Term
Getting more Vitamin K2
Definition
Choose grass fed animal produce
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