Term
Which vitamin prevents bone loss and fractures? |
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Definition
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Term
Decrease in Vitamin D or calcium causes |
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Definition
Decrease in calcium absorbtion |
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Term
Decrease in absorbed calcium decreases what? |
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Definition
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Term
What does decreased serum Ca++ levels cause an increase of? |
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Definition
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Term
What does parathymoid hormone increase the rate of? |
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Definition
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Term
What does increased bone remodelling lead to? |
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Definition
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Term
What is the ultimate effect of increase bone loss |
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Definition
Greater risk of bone fracture |
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Term
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Definition
1. Calcium metabolism 2. Cell differentiation (particularly of collagen/skin epithelium) 3. Immunity |
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Term
Vitamin D and calcium metabolism |
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Definition
Vitamin D enhances calcium absorbtion in the gut and renal tubules |
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Term
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Definition
important for cell mediated immunity and coordination of immune response |
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Term
What can lead to a decrease in bone mass/quality? (2) |
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Definition
1. Early menopausal bone loss 2. Calcium/Vit D deficiency |
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Term
What does a decrease in bone mass/quality lead to eventually? |
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Definition
Low bone mass/impaired bone quality |
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Term
What can also influence a low bone mass/impaired bone quality? |
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Definition
Inadequate peak bone mass |
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Term
With the addition of trauma, what will low bone mass/impaired quality lead to? |
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Definition
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Term
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Definition
The amount of bony tissue present at the end of skeletal maturation |
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Term
What can concentrate mechanical stress in bones? |
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Definition
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Term
What is the relationship of bone fracture occurance and resorbtion cavities? |
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Definition
Bone most likely to fracture at the site of bone resorbtion |
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Term
Causes of inadequate peak bone mass? |
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Definition
1. Genetic factors 2. Inadequate nutrition during growth & development 3. Limited physical activity 4. Diseases/drugs during growth that impair bone aquisition |
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Term
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Definition
light porous bone enclosing large spaces which gives a spongy appearance |
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Term
Post menopausal women and cancellous bone |
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Definition
High rate of cancellous bone loss |
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Term
What can lead to decreased vitamin d synthesis in the aged? (2) |
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Definition
1. Impaired renal function 2. Decreased sunlight exposure |
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Term
What does decreased vitamin D synthesis lead to? |
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Definition
Decreased calcium absorbtion |
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Term
What condition is caused by decreased calcium absorbtion? |
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Definition
Secondary hyperparathymoidism |
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Term
What also causes decreased calcium absorbtion in the aged? (2) |
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Definition
1. Oestrogen deficiency 2. Low dietary calcium intake |
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Term
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Definition
1. Muscle weakness 2. Poor balance 3. Poor eyesight 4. Benzodiazepine use |
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Term
Risk for fractures in a fall (4) |
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Definition
1. Failure to break a fall 2. Falling to the side 3. Age 4. Low bone mass |
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