Term
Phenylephrine
(Neo-Synephrine) |
|
Definition
Actions are specific to different organ sub-receptors
Cardiovascular side effects: Tachycardia, hypertension, dysrhythmias limit therapy |
|
|
Term
|
Definition
Both alpha and beta blockers
used for treating hypertension
Used for effects on vascular smooth muscle-vasodilation, decrease BP
Problem: orthostatic hypotension and rebound tachycardia-give first dose at bedtime
avoid pts with asthma
Hold for bradycardia |
|
|
Term
|
Definition
Activate parasympathetic
adverse effects-toxic nerve gas, organophosphate insecticides
should be avoided in patients with suspected urinary obstruction |
|
|
Term
|
Definition
suppress pns impulses, sns response induced
used for GI disorders-decrease secretion of gastric acid, treat diarrhea
Used to accelerate heart rate, dilate bronchi for asthma (atrovent),reduce salvation before surgery.
Negative impact-urinary retention in men with prostate disorders |
|
|
Term
Benzodiazepines for Anxiety, Insomnia, seizures
Lorazepam
(ativan) |
|
Definition
MUST GIVE PO asses for side effects of drowsiness and dizziness
RESPIRATORY DEPRESSION when given parenterally or in combination with other CNS depressants (alcohol) or if the client has sleep apnea
Avoid in the elderly especially those with comorbidities
used to treat short term anxiety and insomnia |
|
|
Term
Barbiturates as Sedatives
Phenobarbital
(Luminal) |
|
Definition
CNS depressant;rarely used for anxiety/insomnia because of SE and other more effective meds
overdose results in serious respiratory depression, hypotension, shock
Schedule II high risk of dependence
avoid stopping suddenly-withdrawl symptoms
always assess for respiratory depression |
|
|
Term
Misc. drugs for Anxiety/insomnia
Zolpidem
(Ambien) |
|
Definition
Schedule IV controlled substance
Pregnancy Category B-safe
Use with caution and high risk of suicide
rebounds of insomnia if d/c'd
amnesia or sleepwalking
daytime sedation
given before bed |
|
|
Term
Anti seziure
(anticonvulant drugs)
Phenobarbitol & Diazepam |
|
Definition
taken long term, should be gradually reduced if indicated
Barbiturates for halting seizures; Benzodiazepines & others for seizure control in epilepsy |
|
|
Term
|
Definition
Most commonly perscribed for seizures
Narrow range bewteen therapeutic dose &toxic dose
First line in treating status epilepticus
May need to change meds or d/c if pregnant
Ketogenic diet=High fat, low carbs, limits water intake
need blood levels checked |
|
|
Term
Drugs for Mood Disorders: Depression
ECT Electroconvulsive therapy
|
|
Definition
Use when unresponsive to Medications
Antidepressants help to increase levels of serontonin and Norepinephrine
Need to complete physical before can be diagnosed with depression
Most require treatment with psychotherapy and meds |
|
|
Term
Tricyclic Antidepressants
Imipramine
(Tofranil) |
|
Definition
Side effects: orthostatic hypotension and sedation and anticholinergic effects
may take 2-6 wks to occur
suicide potential increase as blood levels increase before peak therapeutic level reached
has more energy to carry out suiced than @ begining when to tired to get out of bed
Contra-indicated-cardiac patients, urinary retention, narrow angle glaucoma |
|
|
Term
Selective serontonin Reuptake Inhibitors
(SSRIs)
Sertraline
(Zoloft)
|
|
Definition
Decreased libido & inability to reach orgasm in men and women (70%)
Need baseline liver tests as is metabolized in liver; need baseline weight as weight gain is typical
May take u to 5 weeks to obtain therapeutic level
Do not stop suddenly |
|
|
Term
Monoamine Oxidase Inhibitors
(MAOIs)
Phenelzine
(Nardil) |
|
Definition
Due to drug-drug &drug to food interactions used only if other drugs are not effective
Antidepressants |
|
|
Term
|
Definition
SIDE EFFECTS:
Orthostatic hypotension, hypertensive crisis when taken with foods containing tyramine (beer, wine, banana's, sausage, aged cheese, yogurt, raisins, chocolate!!!!!!! |
|
|
Term
Bipolar Disorder: Mood stabilizers
Lithium
(Eskalith) |
|
Definition
Narrow therapeutic index- need monitoring of blood levels
compliance is key, lithium toxicity=sodium sweating or dehydration
Low therapeutic window before toxic! |
|
|
Term
Drugs for ADHD
Methylphenidate
(Ritalin) |
|
Definition
Schedule II drug
Monitor-med may cause paradoxical hyperactivity-really good till wears off
insomnia may be a side effect
NOT AT BEDTIME
Poor attention span, behavior control issues & hyperactivity
Treated with CNS stimulants-highten alertness and increase focus |
|
|
Term
Drugs for Psychoses
used for:
Feeling psychotic, abnormal thoughts and thought process, withdrawl from other people
high risk for suicide
|
|
Definition
Compliane is problematic-many donts see themselves as being abnormal
Traditional antipsychotic meds have numberous side effects, including unstable BP, muscle spasms, sedation |
|
|
Term
|
Definition
Atypical antipsychotic agents treatment of choice for both positive and negative symptoms
Pregnancy Category B
Hard to put on regular meds, feel trapped, compliance is huge, usually put in institution |
|
|
Term
Drugs for Degenerative Diseases of Nervous System
|
|
Definition
mediacations given to restore the blance of dopamine and acetylcholine in specific areas of the brain-restore dopamine function |
|
|
Term
Parkinsons is Levodopa
(L-dopa) |
|
Definition
levodopa is a precursor of dopamine synthesis
combine with carbidopa as Sinemet, makes more levodopa availabe to enter CNS |
|
|
Term
Alzheimers Disease
donepezil hydrochloride
(aricept) |
|
Definition
used to slowprogression of Alzheimers symptoms
does not change or reverse symptoms
efficacy is modest at best-slow symptoms
other symptoms treated with atypical antipsychotic agents
NO DRUG WILL CURE ALZHEIMERS |
|
|
Term
|
Definition
chronic inflammatory, auto immune disorder
immune modulating drugs are typically the drugs used to treat this disease |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|