Term
Normal lithium concentrations |
|
Definition
nausea, vomiting, anorexia, abdominal pain, fine hand tremor, mild polyuria/polydipsia, muscle weakness |
|
|
Term
moderate toxicity (1.5-2.5 mEq/L) |
|
Definition
course tremor/twitching, GI upset, vertigo, confusion, sedation/lethargy, hyperreflexia |
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Term
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Definition
seizures --> stupor--> coma --> CV collapse --> death |
|
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Term
|
Definition
at least 7 days (3-5 during acute phase) |
|
|
Term
therapeutic effect of lithium |
|
Definition
14-21 days. doses can be adjusted earlier |
|
|
Term
|
Definition
every 4-7 days, then q 1-3 months |
|
|
Term
increases lithium concentration |
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Definition
diuretics, NSAIDs, ACE inhibitors, TCAs, alcohol, volume depletion, low sodium diet, hypothyroidism |
|
|
Term
decreases lithium concentration |
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Definition
aminophylline, pregnancy, strenuous exercise, hot climate, crash dieting |
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