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Lithium
Overview
8
Audiology
5th Grade
10/23/2013

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Cards

Term
Normal lithium concentrations
Definition
nausea, vomiting, anorexia, abdominal pain, fine hand tremor, mild polyuria/polydipsia, muscle weakness
Term
moderate toxicity (1.5-2.5 mEq/L)
Definition
course tremor/twitching, GI upset, vertigo, confusion, sedation/lethargy, hyperreflexia
Term
severe toxicity (> 2.5)
Definition
seizures --> stupor--> coma --> CV collapse --> death
Term
steady state of lithium
Definition
at least 7 days (3-5 during acute phase)
Term
therapeutic effect of lithium
Definition
14-21 days. doses can be adjusted earlier
Term
monitoring of lithium
Definition
every 4-7 days, then q 1-3 months
Term
increases lithium concentration
Definition
diuretics, NSAIDs, ACE inhibitors, TCAs, alcohol, volume depletion, low sodium diet, hypothyroidism
Term
decreases lithium concentration
Definition
aminophylline, pregnancy, strenuous exercise, hot climate, crash dieting
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