Term
| Name the 6 common Fatty Acids. #C's, double bonds, and where double bonds are located? |
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Definition
Palmitic Acid C16:0 Steric Acid C18:0 Oleic Acid C18:1 (9) Linoleic Acid C18:2(9,12) Linolenic Acid C18:3(9,12,15) Archidonic Acid C20:4(5,8,11,14)
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Term
| How is Lypolysis Regulated? |
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Definition
(+) Epinepherine, Glucagon, Glucocorticoids (-)Insulin, FFA(product) |
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Term
| What tissue does not take up FFA? |
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Definition
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Term
| In what form does FFA travel throught the blood? |
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Definition
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Term
| Where can Glycerol be utilized, and what determines that? |
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Definition
Glycerol Kinase Liver, Kidney, Intestine, Brown Fat, Lactating mamary.
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Term
| What Fatty Acids are essential? |
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Definition
Linoleic and Linolenic Arachidonic is NOT essential because it can be made from Linoleic Acid |
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Term
What does Malonyl-CoA inhibit? |
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Definition
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Term
| How many ATP's are produced and used during β Oxidation? |
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Definition
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Term
| What are the 4 enzymes used in β Oxidation? |
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Definition
End up with Fatty Acyl-CoA that is 2 Carbons shorter. |
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Term
| Acyl-CoA Dehydrogenases and what happens when they are deficient? |
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Definition
>C12, LCAD: Problems appear in infancy. Failure to thrive. Hepatomegaly(Large Kidney). Nonketotic Hypoglycemia. C6-C12, MCAD: Most common deficiency. mild Myopathy(muscle weakness) <C6, SCAD: Very rare. Some infants have failure to thrive. Nonketotic Hypoglycemia. Myopathy. |
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Term
| Carnitine Palmitoyl Transferase Deficienct (CPT) |
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Definition
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Term
During excercise, how long does it take to see symptoms of CPT2?McArdle Syndrome? |
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Definition
CPT2: 60-90min McArdle: 15min |
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Term
| How is CPK affected by CPT2?McArdle Syndrome? |
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Definition
CPT2: CPK levels are usually normal between episodes of myoglouria. McArdle: CPK levels are often elevated between episodes of myogloburia. |
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Term
| What percentage of people with CPT2/McArdle Syndrome have renal failure? |
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Definition
CPT2: 1/4 renal failure due to myogloburia. McArdle: 1/2 renal failure due to myoglonuria. |
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Term
| How is β Oxidation regulated? |
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Definition
(+) FFA, AMP-PK(muscle, liver) (-) Insulin, NADH, FADH2, Malonyl-CoA(Inhibits CPT-I) |
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