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Lipid-Lowering Agents
Lipid-Lowering Agents
13
Pharmacology
Undergraduate 2
02/19/2013

Additional Pharmacology Flashcards

 


 

Cards

Term

Group of fat or fat like substances, insoluble in water

Ex. Alcohol, fatty acids, glycerol, cholesterol

Definition
Lipid
Term
Loosely packed lipids. Act like "scrubbers"- going ard & picking up extra cholesterol & fats in blood vessel and transporting them back to the liver for excretion or re-utilization. This is a good thing! Called "good cholesterol".
Definition
HDL (High Density Lipoproteins)
Term
Tightly packed cholesterol, triglycerides, & lipids- used for energy- can be returned to the liver & recycled. If too much is left over it stays in bloodstream & starts the inflammation process, leads to arthrosclerosis & CAD>
Definition
LDL (Low density lipoproteins)
Term
Combination of glycerol & 3 different fatty acids called neutral fats- when combined w/ proteins they form lipoproteins
Definition
Triglycerides
Term

People who have high triglyceride levels have:

___ LDL Levels

____HDL Levels

Definition

High LDL Levels

Low HDL Levels

Term
For good health you want: ___ LDLs, ____ Triglycerides, ___HDLs
Definition
Low LDLs, Low Triglycerides, High HDLs
Term
Souces of ___ are dietary usually.
Definition
cholesterol
Term
Type of anti-lipid meds:
Definition

HMG-COA Reductase Inhibitors

 

**Best is NO drug--EXERCISE: Lowers triglycerides & LDLs/ Increases HDLs

Term

Lipid- Lowering Agents:

 

HMG-COA Reductase Inhibitors

Prototype:____

Definition
Atorvastatin (Lipitor)
Term

Lipid- Lowering Agents:

 

HMG-COA Reductase Inhibitors

Prototype: Atorvastatin (Lipitor)

 

Indications (2):

Definition
  1. Hyperlipidemia
  2. Usually w/ 1 other risk factor: w/ pts who had poor results w/ diet changes.
Term

Lipid- Lowering Agents:

 

HMG-COA Reductase Inhibitors

Prototype: Atorvastatin (Lipitor)

 

Action (1):

Definition
  1. Blocks the formation of cellular cholesterol.
Term

Lipid- Lowering Agents:

 

HMG-COA Reductase Inhibitors

Prototype: Atorvastatin (Lipitor)

 

Adverse Effects (3):

Definition
  1. Hard on liver
  2. GI Sx
  3. Rhabdomyolysis (muscle breakdown): painful/ can shut down kidneys
Term

Lipid- Lowering Agents:

 

HMG-COA Reductase Inhibitors

Prototype: Atorvastatin (Lipitor)

 

Nursing Interventions (2):

Definition
  1. Teaching s&s
  2. Encourage monitoring of liver enzymes & cholesterol levels.
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