Term
| Statins (HMG-CoA reductase inhibitors) |
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Definition
Statins (HMG-CoA reductase inhibitors)
Simvastatin, Fluvastatin, Pravastatin, Atorvastatin
"HMG-CoA reductase inhibitors
* Inhibit LDL cholesterol production
* Cause a decrease of 20 – 50 % in serum LDL levels
* Reduce serum triglyceride levels" |
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Term
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Definition
Fibrates
Gemfibrozil
"Acts as an agonist at a nuclear receptor (PPAR(alpha) or
peroxisome proliferator activated receptor)
Increases lipolysis (breakdown of lipids) in tissues
resulting in a decrease in LDL" |
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Term
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Definition
Bile acid-binding resins
Cholestyramine, Colestipol, Colesevelam
Anion exchange resins bind to bile acids in the intestine |
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Term
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Definition
Nicotinic acid
Niacin, vitamin B3
"Decreases lipoprotein synthesis in the liver resulting in
a decrease in LDL, and an increase in HDL" |
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Term
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Definition
Ezetimibe
Zetia or Ezetrol
Inhibits absorption of cholesterol from the gastrointestinal tract and thereby decreases total cholesterol, triglycerides and LDL |
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Term
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Definition
Fish Oils
N/A
Decreases production of triglycerides, reduces blood clotting and inflammation |
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