Term
|
Definition
Same as macrolides
binds to 50 ribosomal subunit
inhibits the peptidyl- tRNA from A site to P site |
|
|
Term
What is the drug used in the Lincosamide family? |
|
Definition
|
|
Term
What are the uses of Clindomycin? |
|
Definition
P. caninii
Toxoplasma gondi
Anaerobic infections
Prophylaxis of endocarditis in valvular disease (given before dental surgery)
|
|
|
Term
What are the ADR's of clindomycin? |
|
Definition
neutropenia
Pseudomembranous colitis - c. difficile (SUPERINFECTION)
|
|
|
Term
What is given before dental surgery & why |
|
Definition
Clindomycin
for the prophylaxis of endocarditis in valvular disease |
|
|