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Limbic System
Limbic System notes
77
Anatomy
Graduate
10/01/2014

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Term
what are the 4 overall functions of the limbic system
Definition
processing smell, emotion, memory, spatial mapping, social interaction
Term
what is the function of the cingulate gyrus
Definition
controls motivation, allows shifting of attention from one idea to another, allows mind to see options, cognitive flexibility (go with the flow0
Term
what is the function of the hippocampus
Definition
spatial navigation; creating and filing away declarative memory
Term
what is the function of the dentate gyrus
Definition
involved in forming declarative memory
Term
what is the function of the amygdala
Definition
emotion and mood
Term
describe the role of the hippocampus in learning and memory
Definition
creates and files memory through sensory loop
Term
provide some evidence for the role of the hippocampus in spatial navigation in humans
Definition
Maguire's study of London taxi drivers: posterior hippocampi of taxi drivers were significantly larger relative to those of control subjects
Term
what is the largest part of the bird's brain
Definition
hippocampus
Term
what are the 4 major structures of the limbic system
Definition
cingulate gyrus, hippocampus, dentate gyrus, amygdala
Term
what is the shape of the cingulate gyrus?
Definition
umbrella shape/c shape so that it can have lots of associations to all areas of the cortex
Term
what is the most ancient and primitive part of the brain
Definition
limbic system
Term
what is another tem for the limbic system
Definition
rhiencephalon
Term
what are the major functions of the limbic system in humans?
Definition
memory, learning, social interaction, emotion, spatial mapping
Term
what are the major functions of the limbic system in animals?
Definition
olfaction and spatial mapping
Term
what are the limbic systems emotional functions?
Definition
stores emotional memories, sets the emotional tone of mind
Term
what part of the brain modulates motivation?
Definition
limbic system
Term
how does the limbic system affect social interaction?
Definition
affects bonding and connectedness
Term
name 3 disorders that the limbic system is associated with
Definition
autism, Alzheimer's disease, schizophrenia
Term
does the limbic system affect sleep and appetite cycles?
Definition
yes
Term
if you're scared of a snake even though you've never been bitten, what part of your brain is working?
Definition
limbic system
Term
when I'm feeling unmotivated to study, what part of the brain do I blame/
Definition
limbic system, particularly cingulate gyrus
Term
what structure is just inferior to the cingulate gyrus?
Definition
corpus callosum
Term
why is the cingulate gyrus considered to be part of the limbic system?
Definition
it is connected with other limbic structures and it is involved in the control of motivation. It is also involved in the emotional reaction to painful and aversive events
Term
what is the interface between the decision-making process of the frontal lobe and the emotional world of the limbic system?
Definition
cingulate gyrus
Term
what happens if you have damage to the cingulate gyrus
Definition
akinetic mutism: unable to talk or move
Term
what happens if you have an overactive cingulate gyrus
Definition
Tourette's syndrome, ocd
Term
what is the effect of stimulation of the cingulate gyrus in humans?
Definition
negative or positive feelings
Term
what are the functions of the cingulate gyrus
Definition
source of input/output between limbic system and cortex; allows shifting of attention; helps the mind transition to new ideas; helps the mind see options; allows flexibility
Term
what is the amygdala attached to?
Definition
hippocampus
Term
what things are the hippocampus involved in?
Definition
learning and memory
Term
what is working memory?
Definition
problem solving, cognitive processing
Term
what controls working memory
Definition
prefrontal cortex
Term
what is declarative memory
Definition
all your facts, experiences, and conscious memory
Term
is working memory short term or long term
Definition
short term
Term
is declarative memory short term or long term
Definition
long term
Term
what part of the brain files away new memories as they occur?
Definition
hippocampus
Term
what is procedural memory
Definition
memories of doing, experiencing: hard to put into words
Term
what part of the brain is involved in procedural memory
Definition
cerebellum, basal ganglia
Term
how is memory affected with damage to the hippocampus?
Definition
can't create new declarative memories
Term
what happens to previous declarative memories if you have damage to hippocampus
Definition
you retain old declarative memories, just can't make new ones
Term
what process is used for the hippocampus to form memories?
Definition
long term potentiation
Term
what does LTP stand for
Definition
long term potentiation
Term
what is LTP
Definition
a molecular process that strengthens groups of synapses that are repeatedly used: If you reuse the synapse time and time again, the synapse becomes more efficient.
Term
does LTP explain the storage of memory
Definition
not really
Term
what is the dentate gyrus
Definition
a dense, dark layer of cells at the tip of the hippocampus
Term
what are the important areas of the hippocampus
Definition
dentate gyrus, cornu ammonis, subiculum, entorhinal cortex
Term
what is the sensory loop o fhte hippocampus?
Definition
a pathway that travels form the sensory cortex, through the hippocampus, and back to the sensory cortex that creates memory
Term
describe the sensory loop path
Definition
Information enters the hippocampus between the subiculum and dentate gyrus along the perforant path. The entorhinal axons then synapse on cells in the dentate gyrus. The dentate response by sending axons to the cornu ammonis, which sends fibers to the subiculum. The subiculum sends axons back to the sensory cortex
Term
what is the output area of the hippocampus
Definition
subiculum
Term
what are some diseases that affect the hippocampus?
Definition
Alzheimer's, ischemia, epilepsy
Term
can unilateral damage to the hippocampus cause memory loss
Definition
no, must be bilateral
Term
what are the 2 brain pathologies associated with Alzheimer's Disease
Definition
amyloid plaques and neurofibrillary tangles
Term
what is at the core of an amyloid plaque
Definition
amyloid beta protein
Term
what happens if you lose your hippocampus and amygdala
Definition
severe loss of ability to form new declarative memories
Term
is your hippocampus to blame when you can't remember where you left your keys?
Definition
no
Term
where is the amygdala located
Definition
deep within temporal lobe
Term
what is the amygdala shaped like
Definition
almond
Term
what does the amygdala connect with
Definition
hippocampus, prefrontal area, thalamus
Term
what is the primary function of the amygdala
Definition
emotion
Term
what emotion does the amygdala help us feel
Definition
fear
Term
what does the amygdala do with fear
Definition
couples a learned sensory stimulus with an adaptive response to keep us safe from scary situations
Term
what part of the brain makes me run away when I see a snake?
Definition
amygdala
Term
what makes the amygdala able to influence our mood?
Definition
extensively interconnected with frontal cortex, thalamus, striatum
Term
what happens if you electrically stimulate the amygdala
Definition
causes intense hallucinations, often accompanied by fear
Term
what happens if your amygdala degenerates
Definition
you become unable to recognize expression of fear in human faces, can't identify scary stimuli
Term
what type if information is the primary input to the amygdala
Definition
sensory information that has been processed to show danger signals
Term
to what other parts of the brain does the amygdala tell when something is scary?
Definition
hypothalamus, brainstem autonomic center
Term
what controls the limbic system
Definition
cortex
Term
how does an action that reduces the efficacy of the cortex affect the limbic system
Definition
any action that reduces the efficacy of the cortex affects the limbic system; if the cortex isn't working correctly, the limbic system won't work correctly
Term
how does giving a stimulant help a kid with ADHD?
Definition
the stimulant enables the cortex to have more power to control the limbic system and help the child to calm down. T
Term
what is dyspraxia
Definition
trouble planning and completing fine motor tasks
Term
why do dyspraxic children have difficulty controlling their emotions
Definition
the cortex is impaired so that there is insufficient control of the limbic system
Term
what happens to a kid who has difficulty controlling the limbic system
Definition
they become easily distressed, difficult to control, and overactive
Term
where do we see brain damage in kids with autism?
Definition
limbic system: amygdala and hippocampus
Term
what is abnormal about the appearance of the amygdala and hippocampus in kids with autism
Definition
densely packed neurons that are smaller than normal
Term
when does autism begin
Definition
prenatally
Term
what behaviors are seen in animals when the amygdala is damaged or removed?
Definition
behaviors similar to humans with autism: social withdrawal, compulsive behaviors, failure to learn about dangerous situations, difficulty retrieving information from memory, difficulty adjusting to novel events
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