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The liver plays a central role in |
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consumption of too much alcohol |
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can lead to alcoholic hepatitis or alcoholic cirrhosis |
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First law of thermodynamics |
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energy cannot be created or destroyed |
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the total amount of energy in the universe remains |
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energy can undergo conversions from one form to another, but |
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it cannot be created or destroyed |
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potential, kinetic, chemical |
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capacity to do work because of something's location and the arrangement of its parts |
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potential energy of molecules |
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Second law of thermodynamics |
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energy tends to flow from concentrated to less concentrated forms |
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the cost of concentrating it n one area comes at a greater cost of |
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energy dispersal or dilution somewhere else |
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the total amount of energy is |
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flowing from high-energy forms to forms lower in energy |
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life's primary energy source |
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trap energy from the sun and convert it into chemical bond energy |
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all organisms use the energy stored in the bonds of |
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organic compounds to do work |
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between producers ans consumers |
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measure of degree of disorder in a system |
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as systems lose energy they become |
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The world of life maintains a high degree of organization because |
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it is replenished with energy from the sun |
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the molecules of life do not |
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it takes net inputs of energy to force small molecules to combine into larger ones |
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Participants in Metabolic Reactions |
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reactants, intermediates, products, ATP/Energy carriers, enzymes, cofactors, transport proteins |
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product has more energy than starting substances |
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products have less energy than starting substance |
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When ATP gives up a phosphate group |
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ADP binds to inorganic phosphate or to a phosphate group that was split from a different molecule |
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regenerating ATP by this ATP/ADP cycle helps |
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drive most metabolic reactions |
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reactions do not alter or use up |
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The same enzyme usually works for |
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both the forward and reverse reactions |
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each type of enzyme recognizes and binds to |
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the minimum amount of energy required to get any reaction to the point where it will run spontaneously. with no further energy input |
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for a reaction to occur, an energy barrier must be surmounted |
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may promote acid-base reactions |
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A cellular change, caused by a specific activity, shuts down the |
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activity that brought it about |
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factors influencing enzyme activity |
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temperature, pH, salt concentration, allosteric regulators, co-enzymes and cofactors |
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small increase in temperature increases |
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molecular collisions, reaction rates |
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disrupt bonds and destroy the shape of active site |
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accept electrons and hydrogen ions |
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defined as enzyme-mediated sequences of reactions in cells |
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