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Multicellular organisms' cell division |
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Growth from fertilized cell (Reproduction) Growth Repair |
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Mitosis- results in daughter cells with identical DNA Meiosis- results in non-identical daughter cells, gametes |
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All the DNA in the cell The genetic code for the entire cell/organism |
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-DNA molecules are packaged in chromosomes -Every eukaryotic species has a characteristic # -Somatic cells have 2 sets -Gametes have have as many as somatic cells |
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A complex of DNA and proteins that condenses during cell division |
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Distribution of Chromosomes During Cell Division |
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-DNA is replicated and chromosomes condense -Each duplicated chromosome becomes 2 sister chromatids which separate during division -Centromere where the two chromosomes are attached |
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2 parts of Eukaryotic cell division? |
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Mitosis- division of nucleus Cytokinesis- division of the cytoplasm |
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Cell Cycle (very general phases) |
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Mitotic (M) phase: mitosis and cytokinesis Interphase: growth and DNA replication) |
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-90% of the cell cycle -G1 phase, S phase and G2 phase -Cell grows during all the phases but DNA is only replicated in S phase |
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Prophase Prometaphase Metaphase Anaphase Telophase |
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-Chromatin begins to condense, individual chromosomes (as chromatids) visible -Each chromosome is comprised of 2 sister chromatids joined at the centromere -Mitotic spindle begins to form |
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-Nuclear envelope breaks down -Spindle fibers attach to chromosomes' centromeres in region of kinetochore |
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-Apparatus of microtubules that controls chromosome movement during mitosis -During prometaphase some of the spindles attach to chromosomes at the kinetochore -During anaphase the sister chromatids separate moving down the microtubules -Assembly of spindle fibers begins in centrosome during prophase -An aster extends from each centrosome -The spindle consists of the microtubulues, the centrosomes and the aster |
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-Chromosomes have moved along the spindle fibers and aligned at metaphase plate |
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-Kinetochores of sister chromatids separate at the centromere -Each is pulled to opposite ends of the cell -Each pole of the cell has two genetically identical sets of chromosomes |
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-Nuclear envelopes form around groups of chromosomes -Spindle apparatus disappears -Chromosomes become diffuse again -Cytokinesis is already well underway |
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Cytokinesis (animal vs plant) |
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Definition
-Animals: cleavage, forming a cleavage furrow -Plant: Cell plate forms |
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Cell Cycle Control System |
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Definition
-Cycle is regulated by both internal and external controls -Has "checkpoints" where the cycle stops until signals start it again -Checkpoints at G1 phase, G2 and M phases |
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Definition
-Growth factors stimulate other nearby cells to divide -Density Dependent Inhibition -Anchorage Dependence - must be attached to a substratum in order to divide. |
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