Term
| CK-MB level in serum is used in the diagnosis of myocardial infarction because |
|
Definition
| CK-MB is found mostly in the heart |
|
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Term
A patient that you are managing has had an acute Myocardial Infarction. The patient has near normal
myoglobin levels and CK-MB levels but elevated cardiac troponin levels. These enzyme levels suggests
that the patient had: |
|
Definition
| A myocardial infarction 4-5 days ago |
|
|
Term
| Low levels of albumin in a patient who is eating normally may indicate |
|
Definition
|
|
Term
. Ruling out Acute Myocardial Infarction requires a test with high diagnostic sensitivity, whereas ruling in
Acute Myocardial Infarction requires a test with high diagnostic specificity. This is because, commonly |
|
Definition
| A very sensitive test for myocardial infarction will have many false positives |
|
|
Term
| High levels of serum amylase most likely indicate problems with |
|
Definition
|
|
Term
| High levels of ALT (Alanine Amino Transferase) in serum suggests problems with: |
|
Definition
|
|
Term
| Aspartate Aminotranasferase assays are often done to identify |
|
Definition
|
|
Term
| A patient that you are managing has elevated Cardiac troponin I levels but near normal CK-MB levels |
|
Definition
| A myocardial infarction 4-5 days ago |
|
|
Term
| Which serum indicators will suggest Cardiac Damage? |
|
Definition
| LDH1 will be higher in serum than LDH2 (but this is no longer used). CK-MB Is higher in serum (1-2 days after MI. Or to look for MI from 4-5 days ago look for troponin |
|
|
Term
| Which serum isozymes will suggest bone tumors? |
|
Definition
|
|
Term
| What does it mean if you find high H4 LDH in serum. |
|
Definition
It is the sozyme of LDH found in heart muscle, indicating damage to the heart.
M4 found in liver |
|
|
Term
| What are the structural characteristics of isozymes? |
|
Definition
| same reactions but different primary structures with different kinetic parameters (so Vmax and Km vary) |
|
|
Term
| Why does the world look a little blue to some people taking Viagra? |
|
Definition
| Viagra tries to inhibit phosphodiesterase 5 to reduce cAMP to prolong vasodilation but this ends up inhibiting retina phosphodiesterase as well and ppl see blue. |
|
|
Term
| Which is the better tool for diagnosis of MI in the ER: Serum enzymes or ecg? |
|
Definition
| Serum enzymes because it will tell you if there was damage to the heart muscle. |
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