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-plasma -formed elements - erythrocytes (red blood cells) -leucocytes (white blood cells) -thromocytes (platelets) |
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-fluid portion of blood -about 55% of blood -contains water (90%), plasma protiens, dissolved food waste and gas |
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Blood functions (transport) |
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-O2, CO2 -food -waste -immune cells -hormones |
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blood functions (non-transport) |
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-pH regulation -temperature regulation -fluid volume regulation |
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made by the liver -fibrinogen -globulins -albumins |
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plasma protein -helps clot blood |
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plasma protein -immune response |
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plasma protein -transport fatty acids and steroids by making them water soluble -related to osmotic pressure |
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-manufacture of blood cells -in liver, spleen, thymus, lymph nodes and bone marrow |
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-immature blood cells -like pleuripotent stem cells (PPSC) |
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red blood cells -have no nuclei or organelles -bi-concave for more surface area -made through erythropoeisis (stimulated by erythropoeitin - excreted from kidneys) -live 100-120 days -phagocytes eliminate these cells when they are done -carries 1 million O2 molecules |
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platelets -help with clotting |
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% of erythrocytes by volume in whole blood |
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stimulates RBC production -produced in kidneys -can be used for athletic doping - fatal |
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can be used for athletic doping -makes blood thicker -can be fatal when thick blood is too difficult to pump |
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4 large proteins - 2 alpha and 2 beta -center is iron ("heme") -makes up 97% of RBC |
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white blood cell production in bone marrow |
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-neutrophils -lymphocytes -monocytes -eosinophils -basophils -have nuclei and remove waste, toxins and damaged cells |
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5% phagocytic - after injury come to site |
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1% histamine - increases inflammation at injury site |
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mature in Thymus gland -2 types -helper T - tag the foreign or infected cells and trigger immune response -killer T - attack previously tagged cells |
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produce anti bodies which bind to antigen -antibody/antigen complex neutralizes cell -invader is killed |
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antigens on invaders allow leucocytes to identify and respond to them on an individual basis |
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A, B or AB antigens -get blood type from parents - half from each Rh antigens |
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blood types create antibodies against other types which live in the blood plasma |
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A creates B antibodies B creates A antibodies O creates both A and B antibodies |
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antibodies for a different blood type create this |
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on the surface of red blood cells |
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positive or negative -positive mother = no problem -negative mother = 1st child no problem; subseuqent children can have antibody response if baby is positive |
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antibodies vs Rh (positive in baby) will attack the baby - preventable with Rhogan |
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Location of Salivary glands |
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-parotid - near ears -sublingual - under tongue -submandibular - side under jaw |
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mumps creates what condition of the mouth |
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swelling of parotid salivary gland |
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large bundles of taste buds at back of tongue in a V |
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rough surface for texture and moving food |
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-enamel - outer shell -dentin - 80% of tooth - soft, decays -cementum - outer coating of roots of tooth -pulp - blood vessels and nerves -periodontal ligament-attaches to cementum and lamina dura of mandible (jaw bone) |
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from top R to top L 1-16 then bottom L to bottom R 17-32 |
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top R to top L; A-J then bottom L to bottom R; K-T |
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cranial nerve to anesthetize for tooth work |
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trigeminal nerve location |
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lowest portion called the mandibular branch - enters mandibular foramen and exits mental foramen |
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area where heart sits in the body - behind the sternum |
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visceral pericardium = epicardium parietal pericardium peicardial space - contains pericardial fluid |
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Superior and Inferior Vena Cava enter R atrium through tricuspid valve to R ventricle through pulmonary semilunar valve to Pulmonary trunk to pulmonary arteries (no O2) back to heart through pulmonary veins (w O2) into L atrium through mitral/bicuspid valve into L ventricle through aortic semilunar valve into aorta |
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parachute strings on tricuspid and mitral valves |
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sound of blood crashing into valves AV valves close (between atria and ventricles) |
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sound of blood crashing into valves semilunar valves close (between ventricles and great vessels) |
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flow through heart w sounds and contraction specifics |
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Superior and Inferior Vena Cava enter R atrium atrial systole through tricuspid valve to R ventricle atrial diastole (lub) ventricular systole through pulmonary semilunar valve to Pulmonary trunk to pulmonary arteries (no O2) ventricular diastole (dub) back to heart through pulmonary veins (w O2) into L atrium atrial systole through mitral/bicuspid valve into L ventricle atrial diastole (lub) ventricular systole through aortic semilunar valve into aorta ventricular diastole (dub) |
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heart's conduction system |
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Definition
depolarization begins at sinoatrial node (SA node) in R atrium - signal goes to R and L atriums then signal triggers AV node (atrioventicular node) signal travels AV bundle (bundle of HIS) Purkinje fibers (up the ventricular walls) |
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% of heart "pacemaker" cells |
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120/80 (systole/diastole) |
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cell regaining the charge needed to be able to depolarize again |
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artificial pacemakers (2 types) |
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demand pacing - only initiates if stimulation is needed - monitors heart rate and only kicks in when too slow, fast or irregular rate responsive pacing - stimulates heart constantly - monitors heart rate and responds to need (exercise, etc). |
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heart attack - cardiac muscle dies |
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chest pain due to cardiac insufficiency |
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when valves don't close all the way and sounds are muddled |
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-tunica interna - endothelium - prevents blood vessels from sticking -tunica media - smooth muscle, collagen and elastic fibers - vasoconstriction and vasodilation -tunica externa - connective tissue (outside) |
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-carries blood away from heart -thickest walls -have muscle to pump blood |
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-conducting (elastic) artieries - biggest, pump blood, provide recoil/elastic - distributing arteries - muscular to vasoconstrict and vasodilate - resistance arteries - smallest - minimal tunica externa, scattered smooth muscle - can still vasoconstrict and vasodilate |
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mid-sized to small arteries |
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all gas exchange goes on here - smallest vessels -tissue is completely tunica interna |
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-continuous - intact epithelial lining, glucose and small solutes pass by exocytosis -fenestrated - openings/pores in the cells in the capillary walls, good for filtration and absorption -sinusoids - twisted and irregular capillaries - very leaky - proteins can pass |
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small veins contain valves to prevent backflow flow aided by skeletal muscle |
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collect blood from tissues to send it towards heart thinner walls than arteries, but larger diameter collapse when empty |
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arteries are thicker because |
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can pinch off blood from coming to an area to shunt it to an area where it is needed more |
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as blood travels, blood pressure |
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helps move blood through venous system |
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broken valves in veins allow blood to pool |
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varicose veins of anal canal |
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fragile blood vessels that can burst and cause internal bleeding - can be fatal |
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build-up of uric acid in in joints - the big toe usually |
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-ammonia - most toxic - fish -uric acid - less toxic - birds and reptiles -urea - least toxic - humans and mammals |
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transport urine to bladder from kidney |
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transport urine from bladder to outside body |
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kidneys are behind parietal peritoneum |
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-filters blood plasma -regulates osmolarity - solute concentration -regulates blood volume -secrete erythropoeitin |
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where blood vessels and ureter enter kidney |
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functional unit of kidney -more than a million |
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arriving artery - bigger than efferent so that pressure builds in glomerulus and creates leakage |
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exiting artery - smaller than afferent |
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knot of leaky capillaries - filters out 160 Liters of fluid per day |
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outer layer around glomerulus |
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cover capillaries to form inner wall of glomerulus and create filtration slits |
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proximal convoluted tubule |
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reabsorption through peritubular capillaries |
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reabsorption and secretion |
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glomerulus acts as a filter - blood is under higher pressure because efferent vessel is smaller |
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H2O is reabsorbed into blood through peritubular capillaries where they wrap around convoluted tubules and Loop of Henle depends on active transport towards high salt concentration in medulla |
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substances end up in urine wo filtration from peritubular capillaries to distal convoluted tubule and collecting duct controls pH of blood |
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ureters enter bladder obliquely |
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Definition
prevents backflow and infection |
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