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Lecture Exam #3
Pertussis-Whooping Cough
37
Microbiology
Undergraduate 1
11/19/2011

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Term
Disease of the lower respiratory system is called?
Definition
Pertussis-Whooping cough
Term
Is Pertussis considered a conronic disease?
Definition
yes
Term
What did Pertussis use to be called?
Definition
Cough of 100 days (3 months)
Term
Is Pertussis easily diagnosed in adults?
Definition
No, usually misdiagnosed as bronchitis.
Term
Is Pertussis easily diagnosed in an infant?
Definition
Yes, violent cough
Term
What is the Etiology of Pertussis
Definition
Bordetella pertussis
Term
What is the number one characterisitic of Pertussis?
Definition
Produces numerous exotoxins
Term
What are the names of the two characterisitcs of the organism Pertussis?
Definition
Tracheal cytotoxin, Leukocidin
Term
A characteristic Tracheal cytotoxin does what?
Definition
Damage to cells in the trachea that remove mucus. stops ciliary moving, muscus builds up irration with a cough.
Term
A characteristic Leukocidin does what?
Definition
This organism protects itself kills WBC destroyed by this toxin
Term
What is the Reservoir of Pertussis
Definition
Human
Term
What is the mode of transmission for Pertussis?
Definition
Droplet
Term
Is Pertussis considered a contagious disease?
Definition
Yes, 90% infection rate
Term
S&S What are three stages of disease for Pertussis?
Definition
Catarrhal, Paroxysmal, Convalescence
Term
The Catarrhal is equal to what stage of disease?
Definition
Prodromal
Term
A child with a runny nose, sneezing, itchy throat, eyes watering, drainage in back of throat. And showing signs of a common cold but is really in what stage of disease?
Definition
Catarrhal
Term
A child with a runny nose, sneezing, itchy throat, eyes watering, drainage in back of throat. And showing signs of a common cold but with no cough is really in the Catarrhal stage of disease. Is this child contagious?
Definition
Yes
Term
First stage of disease. Child not vaccinated, inhales bacteria, gets into respiratory tract, attach to cells in trachea, and start producing toxin. Toxin stops cili from moving. What stage of disease is this child in?
Definition
Catarrhal=Prodromal
Term
A kid with a runny nose walks into a classroom with 30 kids,who have not been vaccinated are all kids at risk of getting disease. (whooping cough) when the child shows no S&S of a cough?
Definition
Yes, contagious at this stage Catarrhal stage.l
Term
T or F Usually by the end of catarrhal beginning of Paroxysmal all the bacteria are dead?
Definition
True
Term
During the second stage with is Paroxysmal is equal to what stage of disease?
Definition
Acute
Term
During the Paroxysmal period there is a cough and is the disease communicable or non communicable?
Definition
Noncommunicable
Term
If all the bacteria are dead, but that does not mean cili is moving. The toxin hasn't stopped having an effect. There is a build up of mucus in the chest of the child, irration. Child starts coughing and child is not getting enough oxygen cuz of all the mucus build up in the respiratory tract. So there is a gasp for air and the classic whoop sound. This is called _____stage where the cough begins and continues?
Definition
Paroxysmal=Acute
Term
The catch 22 with whooping cough. The time period where whooping cough is contagious is where there is a time period where there is no coughing. This is in what stage?
Definition
Catarrhal=Prodromal stage
Term
When is the time period when this terrible sounding cough is non communicable?
Definition
Paroxysmal=Acute stage
Term
What are some of the S&S of Pertussis (Whooping cough) for an infant?
Definition
violent cough, shaking, lack of oxygen, turn blue, brain damage, broken ribs
Term
What are some of the S&S of Pertussis (Whooping cough) for an adult?
Definition
S&S of common cold, coughing not as violet, no whoop sound, lasting for weeks or more. diagnosed as bronchitis. Can transmit to an infant, before vaccination and newborn could die.
Term
Convalesce stage of Pertussis is equal to what?
Definition
Recovery. Cough lasting 2-3 months.
Term
When is the best time for treatment of antibiotics for whooping cough?
Definition
Antibiotics before the Paroxysmal stage. Give antibiotics when S&S resemble a common cold. but doctors dont' like to give antibotics due to drug resistance to bacteria.
Term
How do you treat Whooping cough when it's in the Paroxysmal stage with a cough?
Definition
with cough medicine.
Term
What type of vaccine is used for Pertussis?
Definition
Acellular (aP)-this is now the recommended type of vaccine, there is no indication of any adverse side effecgts
Term
Are booster shot recommended for adults and why?
Definition
Yes, to reduce medical cost and so they don't transmit to babies
Term
T or F. Mortality rate is very low but those who do die usually die from secondary infection
Definition
True
Term
Is a high mortality rate more likely to affect an adult or newborn?
Definition
Newborn
Term
What is the effect of primary infection?
Definition
Compromisses a person
Term
What is the most common cause of the secondary infection?
Definition
Streptococcus pneumoniae(pneumonia)
Term
T or F. Is it more likely an adult or infant will die from Pertussis and why? (whooping cough)
Definition
An infant from a secondary infection(streptococcus pneumoniae) pneumonia
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