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Transport of molecules across a membrane utilizing transmembrane proteins |
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The passive movement of molecules across a membrane by way of a transport protein |
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A transmembrane protein that binds molecule on one side of a membrane and transports them to the other side of the membrane by a conformational change. |
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Regardless of the exact mechanism, the conformational changes occur randomly. –Due to random thermal motion of carrier protein –If a solute binds, it is transported |
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A glucose carrier has a maximal transport rate of 10,000 glucose molecules per second. |
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3 factors of faciliated diffusion |
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–The transport rate of the individual carriers –The number of carriers in the membrane –The magnitude of the concentration or electrochemic |
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–Is a transmembrane protein that transports molecules via a passageway or pore that extends from one side of the membrane to the other. –Specific for the substrate they transport |
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Highly selective pores that permit water, but not solutes to move across the membrane by diffusion. |
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–Specific to the ions transported –Ion move according to their electrochemical gradient –Typically have and open and closed conformation |
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Requires an energy input to move the transported solute up a concentration or electrochemical gradient. |
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Primary active transport uses ATP directly as an energy source. |
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Secondary Active Transport |
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Secondary active transport is powered by a concentration gradient or an electrochemical gradient that was previously created by primary active transport |
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The membrane proteins that perform primary active transport function both as transport proteins and as enzymes –Catalyze hydrolysis of ATP to release energy –ATPases –Na+ - K+ ATPase or Na+ - K+ pump |
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The diffusion of H2O through a selectively-permeable membrane separating solutions with different concentrations of solute. •Water may move directly through the bilayer or be assisted by proteins which form water channels. |
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–Total solute concentration of a solution. –Provides a measure of water concentration. –High Osmolarity –Low Water Concentration |
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–The effective solute concentration of a solution. –Relates to non-penetrating solutes |
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–A solution Containing 300 mOsm/L of solutes. –Includes both penetrating and non-penetrating solutes. |
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–A solution containing 300 mOsm/L of solutes. –Does not consider penetrating solutes. |
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–A solution Containing less than 300 mOsm/L of solutes. –Includes both penetrating and non-penetrating solutes. |
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–A solution containing less than 300 mOsm/L of solutes. –Does not consider penetrating solutes. |
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–A solution Containing greater than 300 mOsm/L of solutes. –Includes both penetrating and non-penetrating solutes. |
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–A solution containing greater than 300 mOsm/L of solutes. –Does not consider penetrating solutes. |
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Interior comparetment of a hollow organ or vessel |
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Membrane on the side of an epithelial cell taht faces the lumen of a body cavity; the lumen-facing membrane |
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Barrier between lumen and Interstitial fluid |
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Membrane on the side of an epithelial cell that faces the internal environment and is in contact with interstitial fluid; blood facing membrane |
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A layer of noncellular material that is relatively permeable to most substances; anchors the basolateral membrane and provides physical support for the epithelial layer |
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