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Lecture 6
Memory Mechanisms
9
Physiology
Undergraduate 2
02/13/2011

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Term
divergent
Definition
changes sensitivity
Term
convergent
Definition
enhance responsiveness
Term
presynaptic inhibition
Definition
block Ca channels
open Cl channels
Term
NMDA receptor
Definition
-glutamate binds
-Mg stuck inside-moves when inside depolarized
-large conduction
-easy flow for ions
-longer polarization
-memory mechanism
Term
AMPA
Definition
-glutamate binds
-no Mg
-quick depolarization
Term
memory mechanism
Definition
-glutamate release
-net Na entry depolarizes cell and ejects Mg
-Ca enters cytoplasm
-cell becomes more sensitive to glutamate
-paracrine from postsynaptic cell enhances glutamate release
Term
NR2B show
Definition
better retention
Term
habituation
Definition
-presynaptic decrease in Ca channel activity
Term
sensitization
Definition
presynaptic decrease in K
prolonged presynaptic depolarization and more calcium influx
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