time of exposure to disease before symptoms occur

-mperiod from time of first exposure until you get ill with symptoms

- minimum 9 days     maximum 3 weeks

Example: somebody who visits Kenya doesnt get symptoms until they return to US

period when disease symptoms exhibited

Ex) malaria period after prepatent

mosquito that can transmit malaria to humans

Example: Anopheles inject malaria sporozoite from salivary glands into host

state of dormancy

Example. P.ovale sporozoite enter liver and become hynozoite dormant stage, then 2-3 years later cause relapse of malaria

reoccurrence of previous disease

- sporozoite enters liver, hypnozoite dormant stage 2-3 years, then relapse disease

Example: woman from Italy had disease as young woman, immigrated to USA then had disease reoccur when she was 70 in Cleveland

tree containing quinine in bark, quinine active against malaria

Example: Europeans used quinine from swamp that had cinchona trees to treat people of sickness way back in time.