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Lecture 3
Membrane Proteins
6
Physiology
Undergraduate 2
02/13/2011

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Term
primary active transport
Definition
-requires ATP directly
-ex. Na/K/ATPase pump
Term
secondary active transport pump
Definition
-requires indirect energy input such as concentration gradient
-Na/glucose transporter
Term
carriers
Definition
uniport, symport, antiport
Term
Na/K ATPase pump
Definition
-3Na from ICF bind
-ATPase is phosphorylated wit P from ATP
-3Na released into ECF
-2 K from ECF bind
-P leaves
-2K from ECF released into ICF
Term
Na/glucose transporter
Definition
-Na high outside/glucose high inside
-Na binds to carrier
-this creates a site for glucose
-glucose binding changes carrier conformation
-Na released into cytosol, glucose follows
Term
S4
Definition
voltage sensor
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