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Lecture 31 (03/31/14)
Brock's Microorganisms
19
Microbiology
Undergraduate 3
04/07/2014

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Term
attenuation
Definition
form of transcriptional control by early termination of mRNA synthesis

(initiated after start but before completion of transcription)
Term
leader region
Definition
first portion of mRNA made

can fold into 2 different secondary structures:
one allows further transcription
other causes premature termination
Term
leader sequence of tryptophan operon
Definition
sequence in operon that encodes a short leader peptide, contains tandem tryptophan codons near its terminus which act as an attenuator (if tryptophan is plentiful leader peptide will be synthesized resulting in termination of transcription of operon)
Term
clustered regulatory interspaced short palindromic repeats
Definition
CRISPR
Term
CRISPR
Definition
memory bank of hostile viral sequences alternating with identical repeated sequences

provides resistance to viruses by transcribing it and allowing it to base-pair with invading nucleic acids to target for destruction
Term
virus
Definition
genetic element that cannot replicate independently of a living (host) cell but that possess an extracellular form
Term
obligate intracellular parasites
Definition
how viruses must live ( required to be in a host)
Term
virion
Definition
extracellular form of virus

AKA virus particle
Term
bacteriophage
Definition
virus that infects bacteria
Term
-viridae
Definition
ending for all viral family names
Term
20 to 300 nm
Definition
size of virions
Term
capsid
Definition
protein shell surrounding nucleic acid in virus
Term
capsomeres
Definition
assemblies of a protein or proteins into the smallest morphological unit seen with electron microscope
Term
nucleocapsid
Definition
complex of nucleic acid and protein packaged in the virion
Term
naked
Definition
viruses with no envelope around the nucleocapsid
Term
enveloped
Definition
viruses with lipid layer around nucleocapsid
Term
helical
Definition
the symmetry of rod-shaped viruses
Term
icosahedral
Definition
the symmetry of spherical viruses
Term
icosahedron
Definition
symmetric structure containing 20 triangular faces and 12 vertices that is roughly spherical
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