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Lecture 2
Cartilage
97
Medical
Graduate
01/30/2016

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Term
what does cartilage consist of
Definition
connective tissue (cells and matrix)
Term
types of cartilage (3)
Definition
hyaline (articular)
elastic
fibrocartilage
Term
where can fibrocartilage be found
Definition
at tendinous/ligamentous junctions
Term
how do chondrocytes recieve nutrition
Definition
diffusion-imbibation
Term
what provides the tensile strength to hyaline (articular) cartilage
Definition
collagen
Term
primary collagentype of Hyaline cartilage
Definition
T2
Term
how does hyaline (articular) cartilage recieve its nutrition
Definition
compression and release of pressure
Term
3 zones of collagen fibers in hyaline cartilage
Definition
superficial horizontal
middle random
deep vertical
Term
what is below the deep vertical collagen fibers in hyaline cartilage
Definition
cartilaginous end plate
Term
Hyaline Cartilage: Grade 0
Definition
normal/healthy cartilage
Term
Hyaline Cartilage: Grade 1
Definition
the cartilage has a soft spot/blisters or superficial wear
Term
Hyaline Cartilage: Grade 3
Definition
lesions have deep crevices of more than 1/2 the thickness of the cartilage layer
Term
Hyaline Cartilage: Grade 4
Definition
the cartilage tear is full thickness and exposes the underlying (subchondral) bone
Term
Elastic cartilage is found where (3)
Definition
external ear
epiglottis
larynx
Term
why is fibrocartilage strong
Definition
endogenous collagen and matrix
Term
fibrocartilage contains none of this substanec, which is common to other cartilages
Definition
perichondrium
Term
4 subcategories of perichondrium
Definition
intraarticular
connecting
stratiform
circumferential
Term
what is perichondrium
Definition
dense CT with elastic fibers with a chondrogenic layer beneath it
Term
where is intraarticular fibrocartilage found
Definition
meniscus (knee, wrist, AC, SC)
Term
role of intraarticular fibrocartilage
Definition
space filler to improve geometry of the jt and decrease funciton
Term
what is NOT a role of intraarticular fibrocartilage
Definition
it is not a force absorber
Term
example of connecting fibrocartilage
Definition
IV Discs
Term
role of stratiform fibrocartilage
Definition
friciton spots at muscle/tendon junctions
Term
role of circumferential fibrocartilage
Definition
joint spacers hips and shoulder (Labrum)
Term
purpose of tendon
Definition
connect muscle to bone to transmit force
Term
peritendon is made up of what 2 parts
Definition
paratenon and epitenon
Term
peritendon is subject to stress and friciton which can lead to what
Definition
tendonitis/tenosynovitis
Term
what is the enthesis
Definition
attachement of tendon to bnoe
Term
types of enthesis
Definition
fibrous
fibrocartilgaionous
Term
what is tenosynovitis
Definition
inflmmation of the sheath surrounding the tendon
Term
what is tendonitis
Definition
inflammation of the body of the tendon
Term
what is tendinopathy
Definition
structure of the tendon as a result of stress/strain resulting in pain
Term
what are the 4 zones of fibrocartilage entheses
Definition
1) tendon
2) shift of fibrocartilage zone
3) shift of fibrocartilage zone
4) bone
Term
2 types of fibrous entheses
Definition
periosteal
boney
Term
periosteal fibrous entheses
Definition
tendon fibers attaches to the periosteum
Term
boney fibrous entheses
Definition
direct attachment to the bone
Term
what is the myotendinous junction
Definition
interdigitation of muscle and tendon fibers
Term
the myotendinous junctions is senstive to what
Definition
irritation
Term
where do muscular strian injuries occur
Definition
at the musculotendinous junction
Term
what happens to the myotendinous junction when loads are diminished
Definition
conformational change
Term
role of ligament
Definition
connect bone to bone
Term
the ligament may blend with what 2 structures
Definition
capsule
cartilage (meniscus)
Term
what are ligaments composed of
Definition
primarily fibroblasts (10-20%)
remainder is ECM
Term
ligaments are mainly what type of collagen
Definition
T1 collagen
Term
ligament is mainly T1 collagen with this ligament being the exception
Definition
ligamentum flavum
Term
ligaments are mainly T1 collagen, the ligamentum flavum is an exception, what is made up of
Definition
75% elastin
Term
how are ligaments formed to resist tensile load
Definition
tightly woven bundles
Term
how is collagen oriented in ligaments?
Definition
to the direction of the tensile load
Term
fibrous ligament entheses blend to periosteum via what
Definition
sharpey's fibers
Term
active tension
Definition
contracting
Term
passive tension
Definition
lengthening
Term
as muscle length increases what happens to active tension
Definition
raises from 0 and then decreases to 0 in a parabola
Term
as muscle length increases what happens to passive tension
Definition
increases exponentially
Term
if the velocity is negative and the muscle is lengthening what type of contraction is it
Definition
eccentric
Term
if the velocity is positive and the muscle is shortening what type of contraciton is it
Definition
concentric
Term
if the velocity and length are 0 but force is Not zero what type of contraction is it
Definition
isometric
Term
motions of the sagittal plane
axis of the sagittal plane
Definition
flexion extension
frontal
Term
motions of the frontal plane
axis of the frontal plane
Definition
abduction/adduction
sagittal
Term
motionso of the transverse plane
axis of the transverse plane
Definition
rotational movemetns
vertical axis
Term
what is laod
Definition
force or force applied to a structure
Term
the response of a tissue to a load is determined by what (4)
Definition
magnitude
direction
rate of application
size and composition of tissue subjected to force
Term
what is deformation
Definition
what occurs when an object is subected to a laod
Term
what is load equal to
Definition
stress
Term
what is deformation equal to
Definition
stress
Term
Deformation Load Curve: what is occuring in the toe region
Definition
the tissue's slack is being taken up
Term
Deformation Load Curve: what is occuring in the elastic region
Definition
deformation is occuring but return is still possible
Term
Deformation Load Curve: what is occuring in the plastic region
Definition
deformation is occuring but return is not possible
Term
Deformation Load Curve: ultimate failure point
Definition
it broke
Term
Deformation Load Curve: where is the yield point? what is it?
Definition
end of the elastic region where the tissue will not immediately return to normal state . It may recover in time
Term
If a tissue has a bigger cross sectional area it means it has more resistance to what force
Definition
load
Term
which will deform more a longer or a shorter structure
Definition
longer
Term
the load deformation curve reflects what
Definition
the structural properties
Term
how is tensile force measured
Definition
Newtons (N)
Term
how is compressive force measured
Definition
Pascals (Pa)
Term
what is stress
Definition
the force per cross sectional area
Term
What is strain
Definition
the % change in length or cross sectional area
Term
2 forces in the same direction result in what
Definition
compression
Term
2 forces in the opposite vertical direction result in what
Definition
tension
Term
2 forces in the opposite horizontal direction result in what
Definition
shear
Term
2 forces perpendicular to long axis
Definition
torsional load
Term
what does Young's modulus measure
Definition
measure of the tissues stifness, resistance to external loads, resistance to deformation
Term
Young's modulus is represented how on a tissue's stress strain curve
Definition
slope of the lienar portion of the stress strain curve
Term
Young's Modulus as a formula
Definition
E = change in stress/change in strain for 2 consecutive points in the elastic zone
Term
Cortical Bone: E, stiffness, compliance
Definition
high E
High stiffness
low compliance
Term
Fat: E, stiffness, compliance
Definition
Low E
low stiffness
high compliance
Term
how much force is need to straighten (Deform) tissues in the toe region
Definition
little forces
Term
Why is there little force required to straighten (deform) tissue in the toe region
Definition
PGs and GAGs allow interfibrillar sliding
Term
In the elastic region, what type of relationship does strain have to stress
Definition
linear
Term
What does strain having a linear relationship with stress in the elastic region imply
Definition
collagen is stretched and resists the force load, that the curve refelcts the type of collagen
Term
What is elasticitiy
Definition
material ability to return to its original shape after deformation
Term
what is viscosity
Definition
materials resistance to flow, a fluid property
Term
what is creep
Definition
force applied to a constant level and maintained, deformation will gradually increase
Term
what is stress relaxation
Definition
tissue stretched to a fixed length regardless of load. The force required to maintain the position lessens or relaxes over time
Term
what is hysteresis
Definition
force is applied and removed, the load deformation curve of loading and unloading does not follow the same path
Term
why does the curve of laoding and unloading not follow the same path in hysteresis
Definition
the yield point of the tissue
Term
what is strain rate sensitivity
Definition
property of a tissue to respond differently to different rates of load application
Term
as muscle length increases what happens to total tension
Definition
increases
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