Term
| Immunoglobulin diversity types |
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Definition
-V region diversity
-Junctional diversity
-combinatorial diversity
-somatic hypermutations |
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Term
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Definition
-multiple copies of each gene segment
-varying combinations of gene segments in different recombination events |
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Term
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Definition
| -facilitates imprecise joining of V, D, and J genes whish results in different V gene expression |
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Term
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Definition
| different combinations of heavy and light chain V regions |
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Term
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Definition
| point mutations in V regions genes of activated B cells |
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Term
| Light chain gene segments |
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Definition
-V genes
-J genes
-C genes |
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Term
| heavy chain gene segments |
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Definition
-V genes
-D genes
-J genes
-C genes |
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Term
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Definition
-Ig construction
-occurs in bone marrow
-gene segments are distant from each other (even different chromosomes)
-rearranged and put together in B cells |
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