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Study of the cause of a disease |
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The development of a disease |
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Colonization of the body of pathogens |
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Abnormal state in which the body is not functioning normally |
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may be present for days, weeks, or months |
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permanently colonize the host |
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relationship between normal microbiota and the host |
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one organism benefits and the other is unaffected |
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one organism benefits at the expense of the other |
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competition between microbes |
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How do normal microbiota protect the host? |
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Definition
1.) occupy niches that pathogens might occupy 2.) produce acids 3.) produce bacteriocins |
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proteinaceous toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s) |
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Live microbes applied to or ingested into the body, intended to exert a beneficial effect |
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1.) Same pathogen must be present in every case of the disease 2.) Pathogen must be isolated from the diseases host and grown in pure culture 3.) Pathogen from the pure culture must cause the disease when it is inoculated into a healthy susceptible lab animal 4.) Pathogen must be isolated from inoculated animal and must be shown to be the original animal |
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What are Koch's postulates used to prove? |
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Definition
Cause of infectious disease (Some pathogens cause several disease conditions and some pathogens cause disease only in humans |
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Change in body function that is FELT by a patient as a result of disease |
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Change in body that can be measured or observed as a result of disease |
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Specific group of signs AND symptoms that accompany a disease |
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Disease that is spread from one host to another |
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Disease that is EASILY spread from one host to another |
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Disease that is not transmitted from one host to another |
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Fraction of a population that contracts a disease during a SPECIFIC time "new cases" |
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Fraction of a population HAVING a specific disease at a given time |
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Disease that occurs occasionally in a population |
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Disease constantly present in population (STDs) |
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Disease acquired by MANY hosts in a given area in a SHORT time |
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Immunity in most of a population/certain people have immunity (i.e. immunizations, vaccines) |
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If a person is immunized or have natural immunity, then they cannot be a _________ of the disease |
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Symptoms between acute and chronic i.e. A rash that is subacute has been present for longer than a few days, but less than several months |
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Disease with a period of no symptoms when the causative agent is inactive (herpes) |
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Pathogens are limited to a small area of the body |
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Infection throughout the body |
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Infection throughout the body |
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is a local infection that causes subsequent infection or symptoms in other parts of the body |
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Toxic inflammatory condition arising from the spread of microbes, especially bacteria or their toxins, from a focus of infection |
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Growth of bacteria in the blood |
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Acute infection that causes the initial illness |
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Opportunistic infection after a primary (predisposing) infection |
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No noticeable signs or symptoms (inapparent infection) |
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What are the 10 predisposing factors that make the body more susceptible to disease? |
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Definition
1.) Gender (short urethra in women) 2.) Genetics (sickle cell gene) 3.) Climate and weather (cold weather= more contact) 4.) Fatigue 5.) Age 6.) Lifestyle (sex, drinking, smoking) 7.) Chemotherapy/Radiation 8.)Nutrition 9.) Job (preschool teacher, 1st NS) 10.) Drug therapy (steroids) |
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What are the stages of disease? |
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Numbers of microbes increase = 1.) Incubation period (no s/s) 2.) Prodromal period (mild s/s) 3.) Period of illness (most severe s/s) 4.) Period of decline (s/s) 5.)Period of Convalescence |
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In which stage of disease are you more susceptible to secondary infection? |
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