Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
1. Symptoms + random glucose >200 2. FBS > 126 or random glucose > 200 on two separate occasions 3. 2 hour plasma glucose >200 after 75g of glucose load (Oral glucose tolerance test) |
|
|
Term
|
Definition
older than 80 or CR >1.5 in male and CR >1.4 in female |
|
|
Term
|
Definition
Glipizide (Glucotrol), Glyburide (Diabeta, Micronase), Glimepiride (Amaryl) |
|
|
Term
|
Definition
|
|
Term
#3 Disaccharidase inhibitors - 2 |
|
Definition
- Acarbose (Precose), Miglitol (Glyset) - flatulence, diarrhea - good for old people w/ constipation and postprandial |
|
|
Term
#4 Thiazolidinediones (TZDs) - 2 |
|
Definition
Rosiglitazone (Avandia) (don’t use – heart issues), Pioglitazone (Actos) - fluid retention, weight gain, CHF |
|
|
Term
|
Definition
Repaglinide (Prandin), Nateglinide (Starlix) - lower incidence of hypoglycemia than sulfonyluera |
|
|
Term
#6 ***Glucagonlike peptide analogs (GLP-1) |
|
Definition
Exenatide (Byetta, Bydureon), Iiraglutide (Victoza), Albiglutide (Tanzeum), injection only - WEIGHT LOSS, nausea, bloating, pancreatitis |
|
|
Term
#7 ***Dipeptidyl peptidase IV inhibitors |
|
Definition
Sitagliptin (Januvia), Saxagliptin (Onglyza), lingliptin(Trajenta), Alogliptin (Nesina) - ADJUNCT TO METFORMIN - Less hypoglycemia, no weight gain or fluid retention like TZDs |
|
|
Term
#9 Sodium Glucose Co Transporter 2 (SGLT2) |
|
Definition
Canagliflozin (Invokana), Dapagliflozin (Forxiga) - mono therapy or combo (pee out sugar) |
|
|
Term
|
Definition
Insulin glargine (Lantus), and Insulin detemir (Levemir)***** |
|
|
Term
|
Definition
Insulin aspart (Novolog) Insulin Lispro (humalog) Insulin glulisine (apidra) |
|
|
Term
|
Definition
Humalog (75/25), (50/50) Novolog Mix (70/30) - twice daily before meals |
|
|
Term
|
Definition
- dipstick - (0-2 is okay, recurrent 3+ do 24 hour quantitative) - Normal = 40-80 mg - >150 mg in 24 hrs = ABNORMAL (further eval)**** - > 3.5 g/24 hrs = NEPHROTIC RANGE **** - once it is 800-1000 mg/24 hr, NEED TO REFER - less than 800, just follow and make sure they're on ACE or ARB |
|
|
Term
|
Definition
- 30-300 - determines earliest stages of diabetic nephropathy (2/3 tests) - Microalbuminuria >30mg of albumin/gCr Diabetic nephropathy - Macroalbuminuria (>300 mg), protein is detected on UA or dipstick + (at least 1+, probably 2 or 3+) |
|
|
Term
|
Definition
normal = <30 - microalbuminuria = more than 30 - macroalbuminuria = more than 300 - if more than 30 on 2/3 tests, dx w/ diabetic nephropathy - if more than 300 one time, diagnose w/ diabetic neph |
|
|
Term
|
Definition
- normal = 0-2 RBCs/hpf - 3 or more = microscopic hematuria - if 3 or more - WORKUP |
|
|
Term
|
Definition
- you have to order separate - Hyaline - I don't care (fever, exercise, and diuretics) - RBC casts - glomerular bleeding (glomerulonephritis) - WBC casts - glomerulonephritis or interstitial nephritis - Granular or waxy - degeneration/ESRD ABNORMAL = RBCs or WBCs |
|
|
Term
|
Definition
- presence means at least 4 wbc/hpf - normal 0-2 - abnormal - investigate if person has infection - w/ repetitive negative bacterial culture – may have chronic urethritis, prostatitis (90% due to autoimmune) |
|
|
Term
|
Definition
Male 0.6-1.2 mg/dl, female 0.5-1.1 mg/dl |
|
|
Term
|
Definition
Males = GFR= (140-age) x (kg wt.) -------------------------- (Scr mg/dl) x 72
Females = value for males x 0.85 |
|
|
Term
|
Definition
Males 97-137ml/min/1.73m sq Females 88-128ml/min/1.73m sq |
|
|
Term
|
Definition
- normal = 90 ml/min - 60-89 mL = normal w/o kidney damage - 60-89mL >3mo along with kidney damage=early kidney dz <60mL >3mo = chronic kidney dz (CKD) |
|
|
Term
|
Definition
not in Cr. Of 1.5 and GFR less than 45 |
|
|
Term
Blood glucose - acceptable |
|
Definition
- Fasting 60-130 Preprandial 60-130 Postprandial <200 3 A.M. > 65 |
|
|
Term
|
Definition
ideal 70-100 70-100 < 160 > 65 |
|
|
Term
|
Definition
monocytes = TB neutrohpils = bacteria lymphocytes = viruses |
|
|