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lab7
lab7
22
Medical
Graduate
02/08/2011

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Term
demoplastic definition
Definition
a demoplastic tumor is supported by an extensive connective tissue (collagen is what robbin's mentions) system. Some cancers of the female breast are stony hard or "scirrhous"
Term
-oma suffix denotes?
Definition
benign tumor
Term
adenoma is?
Definition
a benign epithelial neoplasm derived from the glands
Term
papillomas are?
Definition
benign neoplastic growths that appear 'finger like' or 'warty' macro or microscopically
Term
cystadenomas
Definition
adenomas that are cyst-like
Term
polyps
Definition
neoplasm, benign or malignant, produces a macroscopically visible projection above the mucosa
Term
sarcomas
Definition
malignancies that arise in mesenchymal tissue

Gr. sar=fleshy

e.g. fibrosarcoma, chondrosarcoma, leiomyosarcoma, rhabdomyosarcoma.
Term
carcinoma
Definition
derived from any epidermis
Term
pleomorphic ade/sarc/carcinoma vs teratoma
Definition
pleomorphic are usually multiple cell types of only one germ layer
Term
anaplasia
Definition
lack of differentiation. indicative of malignancies
Term
benign tumors look like what?
Definition
the tissue tehy are derived from
Term
what are some defining characteristics of anaplasia?
Definition
-pleomorphism: size of cells differ
-abnormal nuclear morphology
-mitosis (not a strong indicator, however bizarre mitotic figures are indicative)
-loss of polarity
-ischemic necrosis
Term
metaplasia definition?
Definition
replacement of one cell type with another
Term
dysplasia
Definition
disordered growth: loss of uniformity
Term
where do you find nearly all cervical squamous cell carcinomas/epithelial neoplasms?
Definition
T-zone
Term
episomal vs integrated papilloma virus
Definition
episomal = dna not integrated into the genome
integrated = derp

low grade lesions can be associated with either one of these
Term
low grade, productive HPV infection of the cervix are called...(2)
Definition
flat condyloma & cervical intraepithelial neoplasia (CIN) I: collectively called 'low grade intraepithelial lesions.
Term
productive hpv on the vulva/perineum:
Definition
condyloma acuminatum (papillary, cauliflower-like)
Term
koilocytes
Definition
squamous cell infected by HPV that undergoes a number of morphological changes: nuclear enlargement, nuclear hyperchromasia, perinuclear clear zone
Term
high grade productive HPV infection of the cervix are called...
Definition
CIN II and III. these are moderate and severe dysplasia, respectfully. this is also known as carcinoma in situ. These are complete neoplastic transformations, and while they are not metastatic, they have a higher potential for transformation than low grade (CIN I) lesions.
Term
sessile definition
Definition
polyp without a stalk--vast majority of polyps
Term
pedunculated
Definition
polyps with a stalk
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