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Lab quiz 7
bleh
45
Physiology
Undergraduate 3
11/15/2012

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Term
What establishes a vertical osmotic gradient across the renal medulla
Definition
loop of henle
Term
Countercurrent
Definition
the flow in the two closely adjacent limbs of the loop moves in opposite direction
Term
What maintains hyperosmotic gradient?
Definition
the vasa rects through countercurrent exchagne
Term
What diffuse into the descending limb and then back into the medullary tissue?
Definition
sodium and urea
Term
What are walls permeable to?
Definition
H20, Na, urea
Term
Where is the juxtaglomerular apparatus?
Definition
on a nephron where the afferent arteriole meets the thick ascending limb
Term
What is the believed cause of chronic hypertension?
Definition
excessive conversion of angiotensin 2 within the lung endothelial tissues
Term
What is the function of the kidneys?
Definition
to regulate volume, composition and pH of the body fluids
Term
What converts vit D3 into its active metabolite?
Definition
kidneys
Term
What is the site for filtration?
Definition
glomerulus
Term
Where do the glomeruli originate?
Definition
inner cortex and outer cortex
Term
What is better at making concentrated urine?
Definition
juxtamedullary nephron
Term
What has shorter loops of henle?
Definition
cortical nephron
Term
What is fluid called that enters the glomerular capsule?
Definition
ultrafiltrate
Term
In glomerular filtration, what direction to substances move?
Definition
from the blood to the glomerular capsule
Term
What is the main driving force for filtration through the glomerular capillary wall?
Definition
hydrostatic pressure of the blood
Term
What are the three renal transport mechanisms
Definition
filtration, tubular reabsorption, tubular secretion
Term
What is filtration
Definition
the movement of water and plasma solutes from the glomerulus into the glomerular capsule
Term
What is tubular reabsorption?
Definition
when a substance is transported from the filtrate, through tubular cells, and into the blood
Term
What is tubular secretion?
Definition
a substance is transported from peritubular blood, through tubular cells and into the filtrate
Term
xenobiotics
Definition
molecules that are foreign to the body, including toxins and bacteria
Term
Membrane carriers in the _______ membrane of the PCT are able to recognize xenobiotics and transport them into the tubule for secretion
Definition
basolateral
Term
elevated K in the blood stimulates what?
Definition
aldosterone
Term
what is the main function of the proximal convoluted tubule?
Definition
reabsorption
Term
Is Na transport under hormonal control?
Definition
no
Term
PCT is made up of what kinds of cells
Definition
cuboidal with millions of microvilli
Term
Where is water reabsorbed?
Definition
descending limb
Term
What is the interstitial fluid in reference to the descending limb?
Definition
hypertonic
Term
As a result of the descending limb, what occurs?
Definition
filtrate becomes more concentrated and the volume decreses
Term
What does the ascending limb transport?
Definition
Na and Cl
Term
What is the ascending limb impermeable to?
Definition
water
Term
filtrate becomes more ____ as solute is being reabsorbed
Definition
dilute
Term
Where is ADH present
Definition
in the collecting duct
Term
Where is the Na bicarbonate system at work?
Definition
the collecting duct
Term
Proteinuria
Definition
increase in protein count in urine. could be caused by diabetes or renal infections
Term
Glycosuia
Definition
chief cause is diabetes. too much glucose
Term
Tests for ketouria
Definition
When there is a carb deprivation.
Term
Homoglobinuria
Definition
hemoglobin appearing in the urine in the event of a hemolysis in the systemic blood vessels
Term
low osmotic pressure of the urine may cause
Definition
hemolysis and the release of hemoglobin from red blood cells
Term
Bilirubinuria
Definition
large amounts can lead to jaundice. this test is used to diagnose liver or gallbladder problems
Term
Increased levels of bilirubin in the urine may be due to:
Definition
biliary strictures, cirrhosis, gallstones, hepatitis, surgical trauma
Term
What does a positive nitrite tests indicate?
Definition
that bacteria may be present in significant numbers in the urine ( E Coli )
Term
Specific Gravity
Definition
(directly proportional to urine osmolality which measures solute concentration) measures urine density, or the ability of the kidney to concentrate or dilute the urine over that of plasma.
Term
Test for Urobilinogen
Definition
small presence is normal. mostly excreted in stool. liver damage, hepatitis, cirrhosis, increase amount in the urine.
Term
Urine pH
Definition
4.6-8. see if you are at risk for kidney stones or aid in the determination of system acid-base disorders of metabolic or respiratory origin
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