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Lab Final
Ch.6-9
96
Physiology
Undergraduate 2
11/08/2012

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Term
Hematocrit
Definition
% of total blood volume occupied by RBC's; Males=46%, Females=41%
Term
Anemia
Definition
too few RBC's
Term
Causes of Anemia
Definition
B12 deficiency, too little hemoglobin/cell, Iron deficiency, cancer, sickle cell anemia
Term
Polycythemia
Definition
too many RBC's
Term
Causes of Polycythemia
Definition
Low O_2 environment, cancer, Blood doping
Term
Hemoglobin
Definition
molecule with in RBC's that carry O_2; 1Hb=1.34O_2; Male=13.6-17.2 g/dL; Females=11.5-15.0 g/dL
Term
O_2 carrying capacity equation
Definition
Hb X 1.34
Term
Granulocytes
Definition
segmented nuclei and many cytoplasmic granules
Term
Agranulocytes
Definition
large, round nuclei that nearly fill the cell, and don't have cytoplasmic granules
Term
Neutrophil
Definition
WBC; granular; phagocyte
Term
Eosinophil
Definition
WBC; granular; Anti-parasitic
Term
Basophil
Definition
WBC; granular; release Histamine/Heprine-go to infection and attracts all WBC to infection, breaks blood clots
Term
Monocyte
Definition
WBC; travel through tissue-macrophage
Term
Lymphocyte
Definition
WBC; make antibodies to bacteria-specific (B cell); Non-specific bind to any pathogen (T cell)
Term
Antigens
Definition
present on RBC's surface; decides blood group; molecule that stimulates immune cells (WBC's) to produce antibodies
Term
Antibodies
Definition
protein produced by WBC's that reacts against a specific antigen
Term
Agglutination
Definition
clumping of RBC's in response to a reaction btw. an antibody and an antigen
Term
Erythroblastosis Fetalis
Definition
Rh- mom has an Rh+ baby and produces antibodies against Rh+; receives a Rhogam shot, will neutralize the antibodies against the Rh antigens
Term
Eupnea
Definition
normal breathing
Term
Hyperpnea
Definition
increased respiratory rate following exercise
Term
Apnea
Definition
temporary cessation of breathing
Term
Dyspnea
Definition
subjective difficulty in breathing
Term
Hyperventilation
Definition
increased rate/depth of breathing that results in a decrease in blood CO_2 concentration to below normal
Term
Hypoventilation
Definition
inadequate pulmonary ventilation, CO_2 is abnormally increased
Term
Tidal volume
Definition
volume of gas inspired/expired in an unforced respiratory cycle (500mL)
Term
Inspiratory reserve volume
Definition
max. volume of gas that can be inspired during forced breathing in addition to tidal volume
Term
Expiratory reserve volume
Definition
max. volume of gas that can be expired during forced breathing in addition to tidal volume (1000mL)
Term
Residual volume
Definition
volume of gas remaining in the lungs after a max. expiration (1200mL)
Term
Total Lung Capacity
Definition
total amount of gas in the lungs after max. inspiration (600mL)
Term
Vital Capacity
Definition
max. amount of gas that can be expired after a max. inspiration (4800mL)
Term
Inspiratory Capacity
Definition
max. amount of gas that can be inspired after a normal tidal expiration
Term
Functional residual capacity
Definition
amount of gas remaining in the lungs after a normal tidal expiration
Term
Restrictive (breathing) disorders
Definition
vital capacity is reduced to below normal; can't breathe in- Fibrosis/Pneumonia (FEV1= above 80%)
Term
Obstructive (breathing) disorders
Definition
can't breathe out- Asthma/Emphysema (FEV1= below 50%)
Term
Central Chemoreceptors and Peripheral Chemoreceptors
Definition
Central-found in the medulla oblongata
Peripheral-contained w/in small nodules associated w/the aorta and the carotid arteries
Both respond to the changes in PCO_2, pH, and PO_2
Term
A- can donate to
Definition
A-, A+, AB+, AB-
Term
A- can receive blood from
Definition
A-, O-
Term
A+ can donate blood to
Definition
A+, AB+
Term
A+ can receive blood from
Definition
A-, A+, O-, O+
Term
B- can donate blood to
Definition
B-, B+, AB-, AB+
Term
B- can receive blood from
Definition
B-, O-
Term
B+ can donate blood to
Definition
B+, AB+
Term
B+ can receive blood from
Definition
B+, B-, O+, O-
Term
AB- can donate blood to
Definition
AB-, AB+
Term
AB- can receive blood from
Definition
AB-, O-, B-, A-
Term
AB+ can donate blood to
Definition
AB+
Term
AB+ can receive blood from
Definition
AB+, AB-, A+, A-, B+, B-, O+, O-
Universal receiver
Term
O- can donate blood to
Definition
O-, O+, A-, A+, B-, B+, AB-, AB+
Universal donor
Term
O+ can donate blood to
Definition
O+, A+, B+, AB+
Term
O+ can receive blood from
Definition
O+, O-
Term
Aldosterone
Definition
adrenal gland; regulate the concentration of extracellular electrolytes by causing sodium ions to be conserved and potassium ions to be excreted
Term
Renin
Definition
released in response to a decrease in blood flow. Enters blood and converts another circulating protein angiotensinogen to angiotensin 1.
Term
Angiotensin 1
Definition
weak vasoconstrictor
Term
Angiotensin 2
Definition
strong vasoconstrictor; increases BP by increasing TPR; stimulates the release of aldosterone
Term
Vasopressin (ADH)
Definition
posterior pituitary; increases water absorption
Term
Sequence of urine formation
Definition
filtration, reabsorption, secretion
Term
Filtration
Definition
non-discriminate, everything that is dissolved in the blood will be filtered out w/the plasma; excluded are blood cells and proteins
Term
Reabsorption
Definition
very selective; allow body to hang onto things that are important (water, salts, glucose, amino acids) and eliminate those which are unnecessary or harmful (excess H+, waster products, drugs)
Term
Secretion
Definition
substances that may be moved from the peritubular blood to the renal tubule, hastening their elimination
Term
Uncommon components of normal urine
Definition
glucose, protein and blood
Term
Carbohydrates: Digestion begins
Definition
Location: Mouth
Enzyme: Amylase
pH: 7-8
Term
Carbohydrates: Digestion cont.
Definition
NO DIGESTION
Location: Esp/Stomach
Enzyme: Pepsin
pH: 2
Term
Carbohydrates: Digestion ends
Definition
Location: Small Intestine
Enzyme: Amylase
pH: 7-8
Term
Carbohydrates: Final product
Definition
Disaccharides
Term
Proteins: Digestion begins
Definition
Location: Stomach
Enzyme: Pepsin
pH: 2
Term
Protein: Digestion cont.
Definition
Location: Small Intestine
Enzyme: Trypsin
pH: 7-8
Term
Protein: Digestion ends
Definition
Location: Small Intestine
Enzyme: Trypsin
pH: 7-8
Term
Protein: Final product
Definition
Amino Acids
Term
Lipids: Digestion begins
Definition
Location: Small Intestine
Enzyme: Lipase
pH: 7-8
Term
Lipids: Digestion cont.
Definition
Location: Small Intestine
Enzyme: Lipase
pH: 7-8
Term
Lipids: Digestion ends
Definition
Location: Small Intestine
Enzyme: Lipase
pH: 7-8
Term
Lipids: Final product
Definition
Fatty acids and glycerol
Term
Benedict's solutions test for what?
Definition
Starch digestion
Term
Lugol' solutions test for what?
Definition
Maltose digestion
Term
How do Enzymes work?
Definition
Work best at 37 degrees Celsius; break down food by inserting water molecules. Process breaks the chemical bond in food to separate into component parts.
Term
Cholecystekinin (CCK)
Definition
Secreted by: Small Intestine
In response to: partially digested fat
Effects: slows down movement of stomach
Term
Gastrin
Definition
Secreted by: Stomach
In response to: partially digested proteins
Effects: secretes HCl-
Term
Secretin
Definition
Secreted by: small intestine
In response to: partially digested fat
Effects: Aids CCK
Term
What would be found in glomerular filtrate?
Definition
1)Plasma
2)Glucose and amino acids
3)No plasma protein and no blood cells
Term
What effect does vasoconstriction of the afferent/efferent arterioles have on GFR?
Definition
Less blood, pressure, filtrate; save water
Term
What effect does vasodilation of the afferent/efferent arterioles have on GFR?
Definition
More blood, pressure, filtrate
Term
Importance of the Na+/K+ pump in the urinary system
Definition
Is an electrochemical gradient; and is also a cotransport-carrier w/binding site for specific substances
Term
Tubular maximum
Definition
Limited amount of carriers; once a specific substance reaches max. capacity the rest of the substance is secreted
Term
How is water reabsorbed?
Definition
1)Linked to sodium transport-H2O tends to follow Na+
2)Passively reabsorbed by osmosis throughout the tubule
Term
How is urea reabsorbed?
Definition
tube-50%, blood-50%
most waste products are not reabsorbed, but urea is a non-polar
Term
Tubular secretion: direction of movement
Definition
Peritubular capillary -> tubular filtrate
Term
Two ions that are actively secreted when in excess
Definition
Hydrogen and Potassium
Term
Effects of Atrial Natriuretic Hormone
Definition
Dumps Na+, H2O follows
Term
Role of ADH
Definition
1)Changes the permeability of the DCT and the CD allowing more H2O to leave the filtrate
2)No ADH present-hypotonic urine is produced
3)ADH present-hypertonic urine is produced
Term
Role of Aldosterone
Definition
Saves Na+, saves H2O
Term
What is the minimum obligatory urine production daily amount?
Definition
400mL
Term
Micturition
Definition
emptying bladder; urination
Term
Urethra: internal sphincter
Definition
involunary
Term
Urethra: external sphincter
Definition
Voluntary
Term
Renal auto-regulation: intrinsic control
Definition
change diameter of afferent arteriole
Term
What is the role of the Juxtaglomerular apparatus?
Definition
1)Monitors-low Cl-/Na+/H2O concentration
2)Secrets renin -> Ang. 1 -> Lungs -> Ang. 2
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