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T/F An IACUC only needs to have people who know about research methods. |
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T/F Products that are not tested on animals can be sold in most stores for human and animals use. |
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T/F The agency that sets policies regarding the relief of pain and suffering in the event of euthanasia is the Public Health service. |
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T/F It takes 5-7 years for a drug to get approved for human use. |
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NIH has the authority to remove products from the market place and order additional testing. |
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T/F The agency under the PHS that provides grants for research is the National institutes of Health. |
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T/F A barrier facility generally houses SPF animals |
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What is the ideal number of air exchanges per hour in a Laboratory facility? |
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Which of the following groups oversees compliance of Animal Welfare Act? FDA USDA NIH EPA |
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Which of the following biohazards ratings is the most regulated/hazardous to humans and mankind? Biosafety level 1 Biosafety level 11 Biosafety level 111 Biosafety level 1V |
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The term PI refers to the.... Primary investigator principle interest Principle investigator Program idiot. |
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The private non-profit organization the certifies animals facilities as being humane and well run is.. |
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Which government organization under USDA does the actual inspections to facilities? |
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Which light to dark ratio is correct for most animal housing rooms? A. 10hr light 14 hr dark B. 12hrs light 12 hr dark C. 14hr dark 10hr light D. 12 hr dark 12 hr light E. both b/d F. both a/c |
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Definition
E. both 12hr light/ 12hr dark ` |
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Which kind of housing would be used if you need to collect all urine and feces for sampling. |
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What are the three R's of laboratory medicine. What does each R stand for? |
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Reduction: use as fewest animals as possible to achieve your goal. Refinement: require experiments to minimize the effects on the animals normal life. Replacement: Use simplest life forms when ever possible or models. |
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What does IACUC stand for? |
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Institutional Animal Care and use Commite. |
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Originating within the body. Age/Sex/Breed/hereditary |
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Originating outside the body. Temp/Ventilation/ Lighting/ noise |
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Food and Drug Administration |
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Has a well defined microflora-Known exposure. |
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Pathogen free- No microflora |
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Certain pathogen removed but other microflora can be present |
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T/F Newborn rodents normally open their eyes between the 2nd and 3rd week of life. |
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T/F The condition of ringtail in rats is correlated with the level of humidity in the environment. |
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T/F Rats can see colors well and differentiate color shades. |
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T/F Male rats have nipples. |
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T/F Rats do not have post partum estrus. |
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False (20-24hrs after parturition) |
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T/F Cedar shavings should never be used as rats beddings. |
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T/F Mice and rats are cecotropic. |
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What is the best description of Chromodacryorrhoea also know as "red tears". |
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Definition
Caused by a screation from the Harderian gland. (Porphryn) |
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Tyzzer's Dz of rodents is caused by stress and a |
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Rats are weaned at what age? |
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How many brother sister mating's have to be done for an inbred strain? |
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Which of the following is not common outbred stock of rats. Wister Albany Sprauge Dawley Long-Evans |
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Animals have been implanted with specific DNA are called. |
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Female rats housed together will have synchronized estrus, this is called the "BLANK" effect. |
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What is the Gestation period for a rat? |
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What is the gestation period for a mouse? |
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Bile drains directly into small intestines because rats do not have a..... |
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When rat blood is centrifuged what color will the serum be? |
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Name site for blood collection on a mouse. |
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ventral tail vein, retrorbital, saphenous , toenail clip, |
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name some site for blood collection on a rat. |
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submandibular, cardiocentesis (terminal) tail clip, lateral tail vein |
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A ridge that covers the opening from the esophagus that prevents fats from doing what? (It's also another reason why they are so good for toxicology studies). |
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What gland produces "Red Tears" in rats? |
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What is the actual name for the substance the gland produces? |
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Newly pregnant females have a new male put in their cages. What will happen? What is this effect called? |
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Definition
If a female is less than 72hr pregnant and a new male is pheromone is released then they will abort the pregnancy. This Is called the Bruce effect. |
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What condition affect both mice and rates if the husbandry humidity is too low? |
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T/F The scientific name of the rabbit is Oryctolagus cuniculus? |
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T/F Rabbits are very adept at hiding symptoms of pain, therefor it is not necessary to give them pain medication for surgical procedures. |
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T/F The AWA now requires that rabbits be given analgesia/anesthesia is they are used to test eye irritants. |
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T/F Male rabbits are usually larger than females. |
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T/F Rabbits will often get irritation of their hind leg footpads. |
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Definition
False ( rabbits do not have foot pads) |
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T/F Rabbits teeth are Hypsodontic. |
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Definition
true! they are constantly growing meaning you need to make sure you have something for them to chew on . |
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T/F Rabbits cannot vomit. |
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T/F If you do a U/A on a 3 year old rabbit and find Calcium Corbonate crystals, this rabbit needs to be treated for this. |
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False rabbits normally have these crystals |
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T/F Rabbits are heat resistant animals. |
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Definition
False they can get overheated very easily |
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The space between the incisors and premolars is known as... |
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Rabbit ears serve as auditory organs and for what other purpose? |
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Which of the following is most accurate gestation period for rabbits? 19-21 days 21-25 days 29-35 days 41-43 days |
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What are the second set of upper incisors called? |
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A male rabbit is called a .. |
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A female rabbit is called a... |
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Baby rabbits are called... |
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What is unique about the hind limbs of rabbits? |
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Definition
They are longer than the forelimbs, they have no pads, the fibula and tibia are fused |
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Like cats, rabbits are... |
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Parturition in rabbits is.. |
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The most common Bacterial infection in rabbits is.... |
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Definition
Snuffles/ Pasteurella Multocida |
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Which of the following is zoonotic? Pasteurellosis Tularemia Tyzzers Ringworm b/d all of the above |
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When a rabbit breaks its back which vertebra is most likely to have the separation? |
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What is the scientific name for rabbit fever? |
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Why is important to hold rabbits with both hands? |
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Definition
Because they are crazy!! they will try to jump out of your arms in a kicking/twisting motion causeing Posterior paralysis = self breaking of back. |
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What is the scientific name for Hair ball? |
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What can be given to rabbits that are suffering from hairballs? |
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What are night feces? Coprophagia |
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Definition
Ceotropic night feces. where rabbits get most of their nutrients. It and completely different special feces. softer. they contain water nitrogen vitamins electrolyes. occurs in twilight or night hours. |
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What is unique about rabbit neutrophils? |
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T/F common zoonotic dz from the laboratory animal include salmonellosis, dermatophytoses, and scurvy. |
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T/F Guinea pigs should be housed in cages with smooth bottoms to prevent bumble foot. |
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T/F Guinea pig have four toes on their front toes on their front foot and three on their back feet. |
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T/F Hamsters are prone to dental caries because they have molars that are not smooth. |
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T/F Over crowding of hamsters can lead to "wet tail" |
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What is the average gestation time (in days)for guinea pigs? |
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Guinea pigs, like humans lack proper production of what vitamin? |
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Depletion of this vitamin (c) can lead to what? |
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What is the scientific name for guinea pigs? |
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The cells are unique to guinea pigs and may play a role in potential cancer resistance. |
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Guinea pig/Rat/Hamster who has precocious young? |
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Tyzzer's diease of rodents is caused by stress and a .... |
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What breed of guinea pig has long silky hair? |
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What breed of guinea pig has short, coarse hair? |
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Definition
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Hamsters are most active when? |
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Definition
Crepuscular: Twilight hours |
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Which of the following are rodents? Hamsters Guinea pigs Gerbil all of the above |
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What are the scent glands found on the flank of the body? Who has them again? |
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Definition
Costrovertebral scent glands/ hamsters have them |
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What is the most common symptom of hamsters suffering from wet tail? |
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What percent of gerbils will have epilepsy? |
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Why must guinea pigs breed prior 6 mo of age? What happened when you breed them before there 6 mom anatomy wise? |
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Definition
Their pelvic/ pubic synthesis will fuse. Fat fills the pubic/pubis |
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What makes hamsters cheek pouchs so unqie ? |
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Definition
There no lymphatic drainage which make them good for carcinogenic studies. |
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Name some diffreances between hamsters/ gerbils. |
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Definition
Hams- crepuscular twilight hours, need to remove female from male after mating because they will fight. costralvertebral scent glands. Gerbils- diurnal (day), monogamous (mate for life), male can help with raising young [= |
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