Shared Flashcard Set

Details

Lab animal test
Including hamsters,gerbils, mice,rats, rabbit,
103
Veterinary Medicine
Professional
11/19/2013

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Cards

Term
T/F An IACUC only needs to have people who know about research methods.
Definition
False
Term
T/F Products that are not tested on animals can be sold in most stores for human and animals use.
Definition
False
Term
T/F The agency that sets policies regarding the relief of pain and suffering in the event of euthanasia is the Public Health service.
Definition
True
Term
T/F It takes 5-7 years for a drug to get approved for human use.
Definition
False
Term
NIH has the authority to remove products from the market place and order additional testing.
Definition
False
Term
T/F The agency under the PHS that provides grants for research is the National institutes of Health.
Definition
True
Term
T/F A barrier facility generally houses SPF animals
Definition
False
Term
What is the ideal number of air exchanges per hour in a Laboratory facility?
Definition
10-15/hour
Term
Which of the following groups oversees compliance of Animal Welfare Act?
FDA USDA
NIH EPA
Definition
USDA
Term
Which of the following biohazards ratings is the most regulated/hazardous to humans and mankind?
Biosafety level 1 Biosafety level 11
Biosafety level 111 Biosafety level 1V
Definition
Biosafety level IV four
Term
The term PI refers to the....
Primary investigator
principle interest
Principle investigator
Program idiot.
Definition
Principle investigator
Term
The private non-profit organization the certifies animals facilities as being humane and well run is..
Definition
AAALAC
Term
Which government organization under USDA does the actual inspections to facilities?
Definition
APHIS
Term
Which light to dark ratio is correct for most animal housing rooms?
A. 10hr light 14 hr dark
B. 12hrs light 12 hr dark
C. 14hr dark 10hr light
D. 12 hr dark 12 hr light
E. both b/d
F. both a/c
Definition
E. both 12hr light/ 12hr dark `
Term
Which kind of housing would be used if you need to collect all urine and feces for sampling.
Definition
Metabolism cages
Term
What are the three R's of laboratory medicine. What does each R stand for?
Definition
Reduction: use as fewest animals as possible to achieve your goal.
Refinement: require experiments to minimize the effects on the animals normal life.
Replacement: Use simplest life forms when ever possible or models.
Term
What does IACUC stand for?
Definition
Institutional Animal Care and use Commite.
Term
Define intrinsic factor.
Definition
Originating within the body.
Age/Sex/Breed/hereditary
Term
Define Extrinsic Factor.
Definition
Originating outside the body.
Temp/Ventilation/ Lighting/ noise
Term
FDA stands for....
Definition
Food and Drug Administration
Term
Define Gnotobiotic..
Definition
Has a well defined microflora-Known exposure.
Term
Axenic
Definition
Pathogen free- No microflora
Term
Specific Pathogen Free
Definition
Certain pathogen removed but other microflora can be present
Term
Morbidity
Definition
Sickness
Term
Mortality
Definition
Death
Term
T/F Newborn rodents normally open their eyes between the 2nd and 3rd week of life.
Definition
False
Term
T/F The condition of ringtail in rats is correlated with the level of humidity in the environment.
Definition
True
Term
T/F Rats are nocturnal.
Definition
True
Term
T/F Rats can see colors well and differentiate color shades.
Definition
False
Term
T/F Male rats have nipples.
Definition
false
Term
T/F Rats do not have post partum estrus.
Definition
False (20-24hrs after parturition)
Term
T/F Cedar shavings should never be used as rats beddings.
Definition
True
Term
T/F Mice and rats are cecotropic.
Definition
False choprophagia
Term
What is the best description of Chromodacryorrhoea also know as "red tears".
Definition
Caused by a screation from the Harderian gland. (Porphryn)
Term
Tyzzer's Dz of rodents is caused by stress and a
Definition
Bacteria
Term
Rats are weaned at what age?
Definition
3 weeks
Term
How many brother sister mating's have to be done for an inbred strain?
Definition
20
Term
Which of the following is not common outbred stock of rats.
Wister
Albany
Sprauge Dawley
Long-Evans
Definition
Albany
Term
Animals have been implanted with specific DNA are called.
Definition
Transgenic
Term
Female rats housed together will have synchronized estrus, this is called the "BLANK" effect.
Definition
Whitten effect
Term
What is the Gestation period for a rat?
Definition
21-23 days
Term
What is the gestation period for a mouse?
Definition
19-21 days
Term
Bile drains directly into small intestines because rats do not have a.....
Definition
GALLBLADER
Term
When rat blood is centrifuged what color will the serum be?
Definition
yellow, Icterus
Term
Name site for blood collection on a mouse.
Definition
ventral tail vein, retrorbital, saphenous , toenail clip,
Term
name some site for blood collection on a rat.
Definition
submandibular, cardiocentesis (terminal) tail clip, lateral tail vein
Term
A ridge that covers the opening from the esophagus that prevents fats from doing what? (It's also another reason why they are so good for toxicology studies).
Definition
Inability to vomit.
Term
What gland produces "Red Tears" in rats?
Definition
Hardreian Gland
Term
What is the actual name for the substance the gland produces?
Definition
Porphyrin
Term
Newly pregnant females have a new male put in their cages. What will happen? What is this effect called?
Definition
If a female is less than 72hr pregnant and a new male is pheromone is released then they will abort the pregnancy. This Is called the Bruce effect.
Term
What condition affect both mice and rates if the husbandry humidity is too low?
Definition
Ring Tail
Term
T/F The scientific name of the rabbit is Oryctolagus cuniculus?
Definition
True
Term
T/F Rabbits are very adept at hiding symptoms of pain, therefor it is not necessary to give them pain medication for surgical procedures.
Definition
False
Term
T/F The AWA now requires that rabbits be given analgesia/anesthesia is they are used to test eye irritants.
Definition
True
Term
T/F Male rabbits are usually larger than females.
Definition
False
Term
T/F Rabbits will often get irritation of their hind leg footpads.
Definition
False ( rabbits do not have foot pads)
Term
T/F Rabbits teeth are Hypsodontic.
Definition
true! they are constantly growing meaning you need to make sure you have something for them to chew on .
Term
T/F Rabbits cannot vomit.
Definition
True
Term
T/F If you do a U/A on a 3 year old rabbit and find Calcium Corbonate crystals, this rabbit needs to be treated for this.
Definition
False rabbits normally have these crystals
Term
T/F Rabbits are heat resistant animals.
Definition
False they can get overheated very easily
Term
The space between the incisors and premolars is known as...
Definition
Diastema
Term
Rabbit ears serve as auditory organs and for what other purpose?
Definition
Thermoregulation
Term
Which of the following is most accurate gestation period for rabbits?
19-21 days
21-25 days
29-35 days
41-43 days
Definition
29-35 days
Term
What are the second set of upper incisors called?
Definition
Peg/wolf teeth.
Term
A male rabbit is called a ..
Definition
Buck
Term
A female rabbit is called a...
Definition
Doe
Term
Baby rabbits are called...
Definition
Kits
Term
What is unique about the hind limbs of rabbits?
Definition
They are longer than the forelimbs, they have no pads, the fibula and tibia are fused
Term
Like cats, rabbits are...
Definition
Inducted ovulators
Term
Parturition in rabbits is..
Definition
kindling
Term
The most common Bacterial infection in rabbits is....
Definition
Snuffles/ Pasteurella Multocida
Term
Which of the following is zoonotic?
Pasteurellosis
Tularemia
Tyzzers
Ringworm
b/d
all of the above
Definition
Tularemia/Ringworm
Term
When a rabbit breaks its back which vertebra is most likely to have the separation?
Definition
7th vertebra
Term
What is the scientific name for rabbit fever?
Definition
Tularemia
Term
Rabbits urine is...
Definition
Alkalie/ creamy
Term
Why is important to hold rabbits with both hands?
Definition
Because they are crazy!! they will try to jump out of your arms in a kicking/twisting motion causeing Posterior paralysis = self breaking of back.
Term
What is the scientific name for Hair ball?
Definition
Trichobezoars
Term
What can be given to rabbits that are suffering from hairballs?
Definition
Proteolytic enzymes
Term
What are night feces? Coprophagia
Definition
Ceotropic night feces. where rabbits get most of their nutrients. It and completely different special feces. softer. they contain water nitrogen vitamins electrolyes. occurs in twilight or night hours.
Term
What is unique about rabbit neutrophils?
Definition
Pink inclusions
Term
What are they called?
Definition
Psudoesinophil
Term
T/F common zoonotic dz from the laboratory animal include salmonellosis, dermatophytoses, and scurvy.
Definition
False
Term
T/F Guinea pigs should be housed in cages with smooth bottoms to prevent bumble foot.
Definition
True
Term
T/F Guinea pig have four toes on their front toes on their front foot and three on their back feet.
Definition
true
Term
T/F Hamsters are prone to dental caries because they have molars that are not smooth.
Definition
True
Term
T/F Over crowding of hamsters can lead to "wet tail"
Definition
True
Term
What is the average gestation time (in days)for guinea pigs?
Definition
59-72 days
Term
Guinea pigs, like humans lack proper production of what vitamin?
Definition
Vitamin C
Term
Depletion of this vitamin (c) can lead to what?
Definition
Scurvy
Term
What is the scientific name for guinea pigs?
Definition
Cavia Porcellus
Term
The cells are unique to guinea pigs and may play a role in potential cancer resistance.
Definition
Kurloff cells
Term
Guinea pig/Rat/Hamster who has precocious young?
Definition
Guinea pig
Term
Tyzzer's diease of rodents is caused by stress and a ....
Definition
Bacteria
Term
What breed of guinea pig has long silky hair?
Definition
Peruvian
Term
What breed of guinea pig has short, coarse hair?
Definition
Abyssinian
Term
Hamsters are most active when?
Definition
Crepuscular: Twilight hours
Term
Which of the following are rodents?
Hamsters
Guinea pigs
Gerbil
all of the above
Definition
all of the above
Term
What are the scent glands found on the flank of the body? Who has them again?
Definition
Costrovertebral scent glands/ hamsters have them
Term
What is the most common symptom of hamsters suffering from wet tail?
Definition
Diarrhea
Term
What percent of gerbils will have epilepsy?
Definition
20-50%
Term
Why must guinea pigs breed prior 6 mo of age? What happened when you breed them before there 6 mom anatomy wise?
Definition
Their pelvic/ pubic synthesis will fuse.
Fat fills the pubic/pubis
Term
What makes hamsters cheek pouchs so unqie ?
Definition
There no lymphatic drainage which make them good for carcinogenic studies.
Term
Name some diffreances between hamsters/ gerbils.
Definition
Hams- crepuscular twilight hours, need to remove female from male after mating because they will fight.
costralvertebral scent glands.
Gerbils- diurnal (day), monogamous (mate for life), male can help with raising young [=
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