Term
| elevated in increaesd muscle use brkdwn or mass |
|
Definition
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|
Term
| sudden appearence in serum with chest pain and EKg changes suggest myocardial release |
|
Definition
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|
Term
| elevated in AMI rises 8-12 hrs after myocardial damge |
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Definition
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|
Term
| elevated in lymphoma or any disease state where there is cell damage whihc results in low specificity |
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Definition
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|
Term
| first protein marker mlcl to diffuse out of ischemic muscle tissue when low can rule out AMI |
|
Definition
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|
Term
first substance to elevate in AMI
serum increased in renal disease bc cleared by kidneys |
|
Definition
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|
Term
| presence of 2 isoenzymes in serum is very specific for myocardial injury |
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Definition
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|
Term
| test for CHF that is either positive or negative |
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Definition
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|
Term
| space between sinusoids and hepatocytes thru which nutrients and waste diffuse between blood and liver |
|
Definition
|
|
Term
| serum albumin lab test done to dx bc concentration reflects the shift of protein and fluid |
|
Definition
| fibrosis or cirrhosis of the liver |
|
|
Term
| not water soluble bilirubin and is non permanently bound to albumin for transport |
|
Definition
| unconjugated or indirect bilirubin |
|
|
Term
| water soluble bilirubin that directly reacts with color reagent for ,measurement__> attatching to glucoronic acid |
|
Definition
| conjugated bilirubin (direct bilirubin) |
|
|
Term
| covalently permamnently attatched to albumin |
|
Definition
|
|
Term
| enzyme neccesary for the conjugation of bilirubin |
|
Definition
|
|
Term
| what is the likely cause if increased bili is seen wiht increased conjugated bilid |
|
Definition
| obsturction of stone or tumor |
|
|
Term
| increased bili with increased unconjugated bili indicated? |
|
Definition
| impaired hepatocellular function such as severe liver disease, drugs, etOH, cancer shows decreased urobilinogen |
|
|
Term
| genetic variation in which pt has less effective conjugation enzyme normally asymptomatic and normal liver function |
|
Definition
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|
Term
| absence of enzyme for conjugation shows marked hyperbilirubinemia |
|
Definition
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|
Term
| uncertain defect shows modereatly high levels of bilirubin |
|
Definition
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|
Term
| defect of transport of bili from liver cells to bile ducts. shows increased conjugted and unconjugated bilirubin |
|
Definition
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|
Term
| defect in liver cell excretion of bilirubin. shows increased levels of conjugated bili |
|
Definition
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|
Term
| increased in structural liver disease but not in congenital abnormalities |
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Definition
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|
Term
| enzyme found in many tissues increased whnever cells are rapidly dividing very snesitive test for biliary tract obstuction |
|
Definition
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|
Term
good sensitivity for obstructive liver disease and hepatocellular damage, normal levels rule out hepatic metastasis
impt use as an indicator of etoh abuse |
|
Definition
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|
Term
| 2 enzymes most often assoicated wtih hepatocellular damage |
|
Definition
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|
Term
| enzyme released in chronic liver disorders with progressive damage rather than acute liver disease |
|
Definition
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|
Term
| best used as a confiramton of liver disease when AST elevated |
|
Definition
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|
Term
| can be increased in any disease state which there is cell damage or destruction |
|
Definition
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|
Term
| prolonged in severe liver disease due to deficiency of clotting factors |
|
Definition
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|
Term
| protein synthesized by the liver that is decreased in liver disorders |
|
Definition
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|
Term
| glucoprotein which inhibits proteolytic activity of several enzymes deficieny causes emphysema and cirrhosis |
|
Definition
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|
Term
| copper transport protein that when decreased causes copper to deposti and accumulate in tissues |
|
Definition
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|
Term
| synthesized yb rapidly multiplying hepatocytes (aka hepatocarcinoma) |
|
Definition
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|
Term
| tumor marker which circulates in blood if there is rapid multiplication of epitehrlial cells (often used for colon cancer) |
|
Definition
| carinoembryonic antigen (CEA) |
|
|
Term
| low levels are seen as a sign of severe cellular and circulatory disease of the liver |
|
Definition
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|
Term
| increased levels oten seen in liver disease bc of in adequate blood supply to break down |
|
Definition
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|
Term
| disease caused by a virus whose sole or primary target is the liver |
|
Definition
|
|
Term
| sx: nausea, anorexia, fever, malaise, jaundice, increased ALT and AST, and increased bilrubin and alkphos |
|
Definition
|
|
Term
| spread by blood contamination from body fluids and sexual activity |
|
Definition
|
|
Term
| spread via blood not easily spread by sexual contact. high rate of chronicity cirrhosis and hepatocellular carcinoma |
|
Definition
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|
Term
| simple virus that cannot replicate without coinfection of HBV to supply virus syntheic functions |
|
Definition
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|
Term
| liver disorder whcih often is shown after a viral illness such as encephalitis but there is liver cell injury |
|
Definition
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