Term
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Definition
| Dermis, hypodermis, lines cavities, glands, supports epithelial cells |
|
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Term
| Dense Regular CT location |
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Definition
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Term
| Dense Irregular CT location |
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Definition
| dermis, submucosa of digestive tract, capsules around organs |
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Term
|
Definition
| Yellow ligaments of verterbral column, suspensory ligamnet of penis, epiglottis |
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Term
| Elastic CT composition/characteristics |
|
Definition
Bundles of thick elastic fibers
appears yellow when fresh, it is rare, can deform and return to shape
cells are fibroblasts and microphages
elastic fiber |
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Term
|
Definition
| Bone marrow (makes reticular cells, which makes reticular fibers), lymp nodes, spleen |
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Term
| Reticular CT characteristics |
|
Definition
lots of reticular fibers
provides architectural framework, sponge-like, argryophilic, specialized loose CT with lots of reticular fibers
cells are reticular cells
fibers are reticular fibers and collagen type III |
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Term
| Which AA's are unique to collagen |
|
Definition
| hydroxyproline and hydroxylysine |
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Term
| How many polypeptides form a pro-collagen molecule? |
|
Definition
|
|
Term
| What are the peptides in collagen synthesis called |
|
Definition
|
|
Term
| During collagen synthesis what are the special sequences on the protocollagen and when are they cleaved? |
|
Definition
registration peptides are at the ends of of the alpha chains and help 3 chains coil around each other to form a triple-helical molecule called procollagen
they are cleaved in the extracellular space by procollagen peptidase converting procollagen to tropocollagen |
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Term
| What AA's are unique to elastin |
|
Definition
Desmosine and Isodesmosine
these are rare AA's except in elastin
important for cross-linking individual elastin chains |
|
|
Term
| What two proteins are present in elastic fibers |
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Definition
|
|
Term
| How are reticular fibers organized |
|
Definition
| They from delicate silver-staining networks as opposed to bundles like collagen |
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Term
|
Definition
| spleen, lymph nodes, liver, endocrine glands |
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Term
|
Definition
| Loose CT, elastic cartilage, elastic arteries, ligaments, dermis |
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Term
|
Definition
| skin, bone, cartilage, blood vessels, basement membrane |
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Term
|
Definition
| it is the most abundant type and it is found in skin and bone |
|
|
Term
| Where is type II collagen |
|
Definition
|
|
Term
| Where is type III collagen |
|
Definition
| It is found in blood vessels but not by itself, also in embryonic tissues and forms the basis of reticular fiber |
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Term
|
Definition
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Term
|
Definition
Repeating disaaccharides that are linear and mostly sulfated
ex - dermatan sulfate, keratin sulfate, heparin sulfate |
|
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Term
|
Definition
GAG + protein
also can form proteoglycan aggregate w/ hyaluronan GAG backbone attached to PG via link proteins
ex - decorin, aggrecan, perlecan, syndecan |
|
|
Term
|
Definition
Protein + branced carbohydrates
protein component is dominant
plays role in adhesion, binds to integrins, anchored in cell membranes
ex- fibronectin, lamina |
|
|
Term
| Difference between Proteoglycans and Glycoprotein |
|
Definition
| GP is mainly protein while PG is mainly carb |
|
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Term
|
Definition
| it is a non-sulfated GAG, it forms extremely long chains but does not form proteoglycans |
|
|
Term
| What complex molecule is hyaluronic acid a part of |
|
Definition
It can form proteogylcan aggregate by linking to PG via link proteins
not part of PG directly |
|
|
Term
| The importance of ground substance |
|
Definition
| it fills spaces, it's a lubicrant, barrier, very viscous, binds cells to fibers |
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