Shared Flashcard Set

Details

JNC7 guidelines
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16
Pharmacology
Professional
03/27/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
What are the classifications of HTN?
Definition
- Normal - under 120/80
- Pre-HTN - Systolic 120-139 and Diastolic 80 - 89
- HTN stage 1 - Systolic 140-159 and diastolic 90-99
HTN stage 2 - Systolic over 160 and Diastolic over 100
Term
How does and increase in BP increase CVD risk?
Definition
For ages 40-70, every 20 mmHG systolic increase and 10 mmHg diastolic increase doubles CVD risk
Term
Why is ambulatory BP monitoring used?
Definition
To measure white coat HTN, assess drug resistance, hypotension, and other dysfunction
Term
What are major CV risk factors?
Definition
HTN
Cigarette smoking
Obesity (BMI >/ 30)
Physically inactive (desk job)
Dyslipidemia of DMII
Microalbumin or GFR < 60
Age over 55 in men or 65 in women
Family history of CVD (under 55 in men or 65 in women)
Term
What are the areas of target organ damage?
Definition
- Heart - LV hypertrophy, angina, CHF
- Brain - stroke or TIA
- Chronic Kidney Disease
- Peripheral Artieries
- Retinopathy
Term
What are causes of secondary HTN?
Definition
- Sleep apnea due to obesity or metabolic syndrome
- Drug induced
- Chronic Kidney disease - RAAS malfunctions
- Primary Aldosteronism
- Steroid therapy/Cushing syndrome
- Renovascular disease
Term
What lifestyle modifications lower BP?
Definition
Weight reduction
DASH diet
Sodium reduction - 2400 mg/day
Increased physical activity to 30 min/day at least 3x/week
moderation of alcohol to 1-2 drinks/day
Term
What is the goal BP for people with hypertension?
Definition
LESS than 140/90 or 130/80 with diabetes/CKD
Term
What is the basis of HTN therapy?
Definition
Thiazide-type diuretics. Use as initial therapy unless there is a compelling indication
Term
What is the only class of medication not appropriate for Heart Failure?
Definition
Calcium Channel Blocker
Term
Which drugs are recommended for initial treatment of post-MI?
Definition
Beta-blockers, AceI, and aldosterone antagonists
Term
Which 2 drugs are not appropriate for initial treatment of high coronary disease risk?
Definition
ARBs and Aldosterone antagonists
Term
What is the only class of medication not appropriate for initial treatment of diabetes?
Definition
Aldosterone antagonists
Term
Which two drugs can be used for initial treatment of CKD?
Definition
AceI and ARBs
Term
Which two drugs can be used for initial treatment of stroke prevention?
Definition
A diuretic(thiazide) and AceI
Term
What is the difference between hypertensive urgency and emergency?
Definition
Presence of target organ damage in emergency
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