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jf02963
patho test one (ch.6)
49
Nursing
Undergraduate 3
08/30/2012

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Term
Filtration and Osmosis
Definition
The way fluid circulates throughout the body
Term
Hydrostatic Pressure and Osmotic Pressure
Definition
The way water moves between compartments
Term
Thirst Mechanism
Definition
Way to control fluid balance; Osmoreceptors in hypothalamus
Term
Antidiuretic hormone
Definition
promotes reabsoprtion of water into blood from kidney tubules
Term
Aldosterone
Definition
determines reabsorption of sodium ions and water
Term
Atrial natiuretic peptide
Definition
regulates fluid, Na and KCL levels
Term
Congestive heart failure
Definition
could be in the lungs
Term
How much of the body is fluid?
Definition
75%
Term
Edema
Definition
Excessive fluid in the interstitial compartment
- causes swelling of tissue and impair tissue perfusion
- may be localized or throughout the body
- may trap drugs in interstitial fluids
Term
Increased capillary hydrostatic pressure
Definition
- due to higher BP or increased blood volume
- forces fluid out of capillaries into tissue
- cause of pulmonary edema
Term
Loss of plasma proteins
Definition
Particularly albumin; Results in decreased plasma osmotic pressure;
Term
Obstruction of lymphatic circulation
Definition
Causes localized edema
- excessive fluid and protein not returned to general circulation
Term
Increased capillary permeability
Definition
Usually causes localized edema
- may result from an inflammatory response or infection
- histamines and other chemical mediators increase capillary
permeability
Can also result from some bacterial toxins or large burn wounds and result in widespread edema
Term
Effects of edema- swelling
Definition
pale or red in color
Term
Effects of edema- pitting edema
Definition
- presence of excess interstitial fluid
- moves aside when pressure is applied by finger
- depression -- "pit" remains when finger is removed
Term
Increased capillary hydrostatic pressure
Definition
- due to higher BP or increased blood volume
- forces fluid out of capillaries into tissue
- cause of pulmonary edema
Term
Effects of edema- increased body weight
Definition
with generalized edema
Term
Effects of edema- functional impairment
Definition
- restricts range of joint movement
- reduced vital capacity (because fluid is squishing against it)
- impaired diastole
Term
Effects of edema- pain
Definition
- edema exerts pressure on nerves locally
- headache with cerebral edema
- stretching of capsule in organs (kidney, liver)
Term
Effects of edema- impaired arterial circulation
Definition
Ischemia leading to tissue breakdown
Term
Effects of edema- dental practice
Definition
- difficult to take accurate impressions
- dentures do not fit well
Term
Effects of edema- edema in skin
Definition
Susceptible to tissue breakdown from pressure
Term
We lose water routinely when we....
Definition
- breathe
- as humidified air leaves the body
- sweat to cool the body
- urinate or have a bowel movement
Term
Dehydration - insufficient body fluid
Definition
Inadequate intake, excessive loss or both
- Fluid loss measured in body weight change and output
- Dehydration more serious in infants and older adults
- Water loss -- loss of electrolytes and proteins (ex:diarrhea)
Term
Dehydration - Causes
Definition
- Vomiting and diarrhea and excessive sweating
- Diabetic ketoacidosis (osmotic diuresis and lyte loss)
- Insufficient water intake (older adults or unconscious)
- Use of concentrated formula in infants
Term
Manifestations of Dehydration
Definition
- decreased skin turgor and dry mucous membranes
- sunken eyes
- sunken fontanelles in infant
- lower blood pressure, rapid weak pulse
- increased hematocrit
- increased temperature
- decreasing level of consciousness
- urine: low volume and high specific gravity
Term
Hematocrit
Definition
Lab value that shows percentage of RBCs in blood
Term
Compensation for fluid loss
Definition
- increasing thirst and heart rate
- constriction of cutaneous blood vessels
- producing less urine that is concentrated
Term
Third Spacing of Fluid
Definition
Fluid shifts out of the blood into a body cavity or tissue and can no longer reenter vascular compartment
- high osmotic pressure of interstitial fluid as in burns
- increased capillary permeability (some gram neg infections)
If you lose fluid, heart rate goes up - tacchycardia
- always lose from vascular space
Term
Sodium
Definition
- primary cation in ECF
- Sodium diffuses between vascular and interstitial fluids
- Transport into and out of cells by sodium-potassium pump
- actively secreted into mucus and other secretions
- exists in form of sodium chloride and sodium bicarbonate
- ingested in food and beverages
Term
Low sodium levels
Definition
Cause fluid imbalance in compartments
- fatigue, muscle cramps, abdominal discomfort or cramps,
nausea, vomiting
Term
Decreased osmotic pressure in ECF compartment
Definition
Fluid shift into cells
- hypovolemia and decreased blood pressure
Cerebral edema
- confusion, headache, weakness, seizures
Term
Hypernatremia
Definition
Cause is imbalance in sodium and water
- insufficient ADH (diabetes insipidus)
- results in larde volume of dilute urine
- loss of thirst mechanism
- watery diarrhea
- prolonged periods of rapid respiration
- ingestion of large amounts od sodium without enough water
Term
Effects of Hypernatremia
Definition
- weakness, agitation
- dry, rough mucous membranes
- edema
- increased thirst (if thirst mechanism is functional)
- increased blood pressure
Term
Potassium Imbalance
Definition
- Major intracellular cation
- Serum levels are low with a narrow range
- Ingested in foods
- Excreted primarily in urine
- Insulin promotes movement of potassium into cells
- Levels influenced by the acid-base balance
- Abnormal potassium levels cause changes in cardiac conduction and are LIFE THREATENING
Term
Effects of Hypernatremia
Definition
- weakness, agitation
- dry, rough mucous membranes
- edema
- increased thirst (if thirst mechanism is functional)
- increased blood pressure
Term
Fluid deficit- dehydration
Definition
Water loss: loss of electrolytes and proteins (diarrhea)
Causes:
-vomiting, diarrhea, excessive sweating
-diabetic koto acidosis (osmotic diuretics and lyte loss)
-insufficient water intake (older adults and unconscious)
-use of concentrated formula in infants
Term
dehydration
Definition
lack of water in the tissues in the vascular space
Term
manifestations of dehydration
Definition
-dereased skin turgor and dry mucous membranes
-if you pinch skin and it stays that is a sign of dehydration
-sunken eyes
-sunken fontanelles in infant
-lower blood pressure, rapid weak pulse
-increased hematocrit
-increased temperature
-decreasing level of consciousness
-urine: low volume an dhigh specific gravity
Term
compensation for fluid loss
Definition
-increasing thirst and heart rate
-constriction of cutaneous blood vesses
-producing less urine that is concentrated
Term
third spacing of fluid
Definition
Fluid shifts out og the blood into a body cavity or tissue ad can no longer reenter vascular compartent
-high osmotic pressure of interstitial fluid as in burns
-increased capillary permeability (some gram-negative infections)
**if you lose fluid (always from the vascular space), heart rate goes up (tacchycardia)
Term
Sodium review
Definition
-primary cation in ECF
-sodium diffuses between vascular and interstitial fluids
-transport into and out of cells by sodium-potassium pump
-actively secreted into mucus ad other secretions
-exists in form of sodium chloride and sodium bicarbonate
-ingested in food and beverages
Term
Hyponatremia
Definition
Low sodium levels
-cause fluid imbalabce in compartments
- fatigue, muscle cramps, abdominal discofort or cramps, nausea, vommiting
Term
Fluid deficit- dehydration
Definition
Water loss: loss of electrolytes and proteins (diarrhea)
Causes:
-vomiting, diarrhea, excessive sweating
-diabetic koto acidosis (osmotic diuretics and lyte loss)
-insufficient water intake (older adults and unconscious)
-use of concentrated formula in infants
Term
dehydration
Definition
lack of water in the tissues in the vascular space
Term
manifestations of dehydration
Definition
-dereased skin turgor and dry mucous membranes
-if you pinch skin and it stays that is a sign of dehydration
-sunken eyes
-sunken fontanelles in infant
-lower blood pressure, rapid weak pulse
-increased hematocrit
-increased temperature
-decreasing level of consciousness
-urine: low volume an dhigh specific gravity
Term
compensation for fluid loss
Definition
-increasing thirst and heart rate
-constriction of cutaneous blood vesses
-producing less urine that is concentrated
Term
third spacing of fluid
Definition
Fluid shifts out og the blood into a body cavity or tissue ad can no longer reenter vascular compartent
-high osmotic pressure of interstitial fluid as in burns
-increased capillary permeability (some gram-negative infections)
**if you lose fluid (always from the vascular space), heart rate goes up (tacchycardia)
Term
Sodium review
Definition
-primary cation in ECF
-sodium diffuses between vascular and interstitial fluids
-transport into and out of cells by sodium-potassium pump
-actively secreted into mucus ad other secretions
-exists in form of sodium chloride and sodium bicarbonate
-ingested in food and beverages
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